Trypanosoma lewisi: Body weight gains and food consumption of folate-deficient rats

Aboko-Cole, Georgiana F.; Lee, Clarence M.

doi:10.1016/0020-711x(74)90056-1

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2015

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Cited by 2 publications

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“…Though folate intake is not directly related to animal weight, it can be concluded that severe folate deprivation has an impact on overall health status, which results in a reduced feed intake, leading to a decrease in body weight. These observations are consistent with previous reports on folate-depleted rats [18,32].…”

Section: Discussionsupporting

confidence: 94%

Folates from metabolically engineered rice: A long-term study in rats

Kiekens

Blancquaert

Devisscher

et al. 2015

Mol. Nutr. Food Res.

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Section: Discussionsupporting

confidence: 94%

Folates from metabolically engineered rice: A long-term study in rats

Kiekens

Blancquaert

Devisscher

et al. 2015

Mol. Nutr. Food Res.

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Trypanosoma lewisi, Trypanosoma rhodesiense: Mitotic activity in normal and folic acid deficient rats

Aboko-Cole

Lee

1975

Z. F. Parasitenkunde

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Ten experiments were performed to compare mitotic activity in livers of rats infected with Trypanosoma rhodesiense and Trypanosoma lewisi. The host dietary groups were: (1) complete of full complement; (2) folic acid deficient, and (3) pair-fed or calorically restricted. Liver mitotic counts of T. lewisi-infected rats fed complete and pair-fed control diets showed a high degree of significance over that of control rats. From days 35 to 55, liver mitotic counts of T. lewisi-infected rats deficient in folic acid showed an average of 16 +/- 2 mitotic phases as compared to 9 +/- 2 for livers of uninfected animals. Liver mitotic counts of T. rhodesiense-infected and non-infected rats fed complete and pair-fed control diets showed that there were essentially no differences in the mitotic counts from that seen in liver from control, uninfected animals. On day 25 (day 5 of infection), folic acid-deficient infected rats showed a significantly higher number of dividing cells than the controls. Folate was measured in isolated, washed T. lewisi and T. rhodesiense cells. T. lewisi and T. rhodesiense contained 9.6 ng folate per 10(8) cells and 6.2 ng of folate per 10(8) cells respectively. Metabolic products of T. lewisi contained an average of 0.51 ng of folate per 10(8) trypanosomes. T. rhodesiense metabolic products contained 0.3 ng of folate per 10(8) trypanosomes.

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Trypanosoma lewisi: Body weight gains and food consumption of folate-deficient rats

Cited by 2 publications

References 6 publications

Folates from metabolically engineered rice: A long-term study in rats

Folates from metabolically engineered rice: A long-term study in rats

Trypanosoma lewisi, Trypanosoma rhodesiense: Mitotic activity in normal and folic acid deficient rats

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