Trivial or Terrible? The Psychosocial Impact of Psoriasis

Fried, Richard G.; Friedman, Steven; Paradis, Cheryl M.; Hatch, Marjorie; Lynfield, Yelva L.; Duncanson, Carol; Shalita, Alan R.

doi:10.1111/j.1365-4362.1995.tb03588.x

Cited by 104 publications

(84 citation statements)

References 12 publications

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“…Previous studies have shown that approximately half of the subjects were found to be depressed and anxious with the diagnosis of psoriasis 27 , and that psoriasis patients suffered higher rates of depression and body cathexis problem 28 . In the current study, depression and stress had an impact on psoriasis at baseline.…”

Section: Discussionmentioning

confidence: 99%

Impact of Psoriasis on Quality of Life: Relationship between Clinical Response to Therapy and Change in Health-related Quality of Life

et al. 2010

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Section: Discussionmentioning

confidence: 99%

Impact of Psoriasis on Quality of Life: Relationship between Clinical Response to Therapy and Change in Health-related Quality of Life

et al. 2010

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“…4 The inconvenience of phototherapy treatment regimens, the fear of toxic effects on organs with both short-and longterm use of many systemic agents, and the highly visible nature of this disease negatively affect multiple facets of healthrelated quality of life (HRQL). [5][6][7][8][9][10][11] A study by Rapp ture of the impact of this disease, both physically and mentally. There is a significant need for psoriasis therapies not only to reduce the visible symptoms of psoriasis but also to reduce subjective symptoms such as itching, an underrecognized key symptom, [12][13][14][15] and to improve patients' functional status and their physical and emotional well-being.…”

Section: Discussionmentioning

confidence: 99%

Efficacy and Safety Observed During 24 Weeks of Efalizumab Therapy in Patients With Moderate to Severe Plaque Psoriasis

Menter¹

2005

Arch Dermatol

199

221

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“…1 The morbidity associated with psoriasis is well documented in terms of its impact on patients' quality of life. [2][3][4] Many patients experience problems with body image, self-esteem and selfconcept, poor psychological adaptation, and feelings of stigmatization, shame, and embarrassment concerning their appearance. 2,5,6 The disease also places an economic burden on patients, particularly those with severe psoriasis, because they incur out-of-pocket expenses.…”

Section: Soriasis Is a Chronic In-mentioning

confidence: 99%

Balancing the Benefits and Risks of Drug Treatment

Seston¹,

Ashcroft²,

Griffiths³

2007

Arch Dermatol

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To examine the extent to which the attributes of a treatment affect patients' choice of treatment for psoriasis and the magnitude and nature of trade-offs between risks and benefits of treatment.Design: A questionnaire, including a stated-preference, discrete choice experiment, was used to elicit patients' preferences for the treatment of psoriasis. Setting: Dermatology clinics in England.Patients: A total of 126 patients with psoriasis.Main Outcome Measures: Preferences of patients for, and trade-offs between, the 6 attributes of time to moderate (50%) improvement, relapse, and risks of experiencing skin irritation, high blood pressure, liver damage, and skin cancer. Results: The mean age of respondents was 47.6 years, and the mean duration of psoriasis was 23 years. All 6 attributes were important factors affecting choice of treatment. The results indicated that patients with psoriasis prioritized low risk of skin cancer (␤=−0.054; PϽ.01) and liver damage (␤ = −0.054; P Ͻ .01) and preferred treatment that resulted in a shorter time to achieve a moderate improvement (␤=−0.034; PϽ.01) over a longer time to relapse (␤=0.028; PϽ.01). Patients were most willing to wait longer for a treatment to work if the likelihood of skin cancer or liver damage was reduced.Conclusions: This study shows that treatment attributes influence patients with psoriasis in their choice of treatment. The results of the discrete choice experiment presented herein indicate that most respondents would be willing to trade between different aspects of treatment to achieve improvements in their psoriasis and minimize the risks of adverse events.

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Trivial or Terrible? The Psychosocial Impact of Psoriasis

Abstract: Psoriasis does appear to cause significant psychosocial morbidity. Greater awareness by physicians and more comprehensive treatment addressing these psychosocial components may avert, or at least minimize, some of these negative sequelae.

Cited by 104 publications

References 12 publications

Impact of Psoriasis on Quality of Life: Relationship between Clinical Response to Therapy and Change in Health-related Quality of Life

Impact of Psoriasis on Quality of Life: Relationship between Clinical Response to Therapy and Change in Health-related Quality of Life

Efficacy and Safety Observed During 24 Weeks of Efalizumab Therapy in Patients With Moderate to Severe Plaque Psoriasis

Balancing the Benefits and Risks of Drug Treatment

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