Triterpenoids from Pyrethrum tatsienense.

Abstract

Terpenes U 0200Triterpenoids from Pyrethrum tatsienense. -Triterpenoids (I) and (II) are isolated from an alcoholic extract of the whole plant of Pyrethrum tatsienense together with 8 known components. -(YANG, A.-M.; LIU, X.; LU, R.-H.; SHI*, Y.-P.; Pharmazie 61 (2006) 1, 70-73; Lanzhou Inst. Chem. Phys., Chin. Acad. Sci., Lanzhou 730000, Gansu, Peop. Rep. China; Eng.) -M. Bohle 18-175

Dammarane- and taraxastane-type triterpenoids fromSaussurea oliganthaFranch

“…The ester group in 1 could be further deduced as a palmitoyl moiety from the characteristic signal at d 173.7 (C-1 0 ) in the downfield region of the 13 C NMR spectrum (Table 1), as well as a saturated long-chain feature: a methyl signal at d 0.86, several methylene signals at d 1.23 and 2.26 (t, J ¼ 7.4 Hz, H-2 0 ) in the 1 H NMR spectrum. 2,3 In addition to the long-chain ester group, the multiplicities of carbon signals were determined by the DEPT experiment, which revealed the presence of eight methyls, 10 methylenes, six methines, and six quaternary carbons. The 13 C NMR spectral data of 1 showed close similarity to 3b-acetyl-20,25-epoxydammarane-24a-ol.…”

Two Prenylated and C-Methylated Flavonoids fromTripterygium wilfordii

“…Our ongoing phytochemical study of T. wilfordii resulted in the isolation of two new prenylated and C-methylated flavanones, (±)-5,4′-dihydroxy-2′-methoxy-6′,6′′-dimethypyrano(2′′,3′′:7,8)-6-methyflavanone (1) and (2S)-5,7,4′-trihydroxy-2′-methoxy-8,5′-di(3methyl-2-butenyl)-6-methyflavanone (2) (l " Fig. 1), along with 10 known compounds, namely, friedelin [6], betulinic acid [7], βamyrin [8], oleanolic acid [9], kaempferol [10], β-sitosterol, nhexadecanoic acid [11], methyl hexadecanoate [11], n-octadecanoic acid [12], and n-tritriacontanoic acid [12]. The present paper reports the isolation and structural elucidation of the new prenylated methylflavones as well as an evaluation of their inhibitive activity on LPS-triggered RAW cell NO production, their antiproliferative activity against the tumor cell lines ZR-75-1 and HT-29, and their bacterial inhibition activity against Escherichia coli strain DH5-alpha.…”