Triterpenes from Licania licaniaeflora

Triterpenoid saponins from Pteleopsis suberosa stem bark

“…Compounds 1-4 resulted new natural products and were identified by 1D, 2D NMR spectroscopy, and ESI-MS analyses while the others compounds are known triterpenes identified by comparison of their NMR data with those reported in the literature as trachelosperidoside E-1 (5) (Fumiko and Tatsuo, 1987), arjunglucoside I (6) (Zhou et al, 1992), sericoside (7) (Terreaux et al, 1996), arjunetin (8) (Braca et al, 2001), arjunglucoside II (9) (Jayasinghe et al, 1993), bellericoside (10) (Nandy et al, 1989), sericic acid (11) (Bombardelli et al, 1974), arjungenin (12) (Jossang et al, 1996), and trachelosperogenin (13) (Mahato et al, 1992).…”

Chrysobalanaceae: traditional uses, phytochemistry and pharmacology

“…Licania densiflora myricetin (1), myricetin-3-rhamnoside, myricetin-3-glucoside, myricetin-3-galactoside, myricetin-4'-methoxy-3-rhamnoside, myricetin-3',5'-dimethylether-3-rhamnoside, myricetin-3'-methylether-3-galactoside, myricetin-3'-methylether-3-glucoside, myricetin-3',5'-dimethylether- (2), quercetin-3-rhamnoside, quercetin-3-glucoside, narigenin-8-hydroxy-4'-methyl ether, catechin (Braca et al, 1999a;Braca, 2001b) Licania heteromorpha myricetin-3-galactoside, myricetin-4'-methoxy-3-rhamnoside, myricetin-3,4'-di-O-α-Lrhamnopyranoside, myricetin-4'-methyl ether-3-O-β-D-galactopyranoside, myricetin-4'-methoxy-3-galactoside, myricetin-4'-methoxy-3-glucoside, myricetin-7-methyl ether-3,4'-di-O-α-L-rhamnopyranoside, betulinic acid, alphitolic acid (Braca et al, 1999b;Braca et al, 1999c) Licania licaniaeflora kaempferol-3-(2''-xylosyl)-rhamnoside, kaempferol-3-rhamnoside, myricetin-3-arabinoside, myricetin-3-galactoside, dihidromyricetin-3-rhamnoside, quercetin-3-rhamnoside, quercetin-3-arabinoside, 8-hydroxy-narigenin, taxifolin-3-rhamnoside, oleanolic acid, maslinic acid, oleanolic acid 3-O-arabinoside, betulinic acid, arjunetin, tomentic acid glucosyl ester, pomolic acid, olean-12-en-2α,3β-diol (Braca et al, 2002, Braca et al, 2001a, Bilia et al, 1996a Licania pittieri quercetin (2), quercetin-3-rhamnoside, quercetin-3-arabinoside, quercetin-3-galactoside, quercetin 3-glucoside, catechin, epicathechin, ursolic acid, oleanolic acid (Bilia et al, 1996a;Mendez et al, 1995) Licania pyrifolia kaempferol (3), kaempferol-3-rhamnoside, kaempferol-3-arabinoside, kaempferol-3-(2''-xylosil) rhamnoside, hypoletin, 8-hydroxy-eriodictyol, 8-hydroxy-narigenin, myricetin (1), myricetin-3-rhamnoside, myricetin-3-(2''-xylosyl)rhamnoside, quercetin (2), quercetin-3-rhamnoside, quercetin-3-arabinoside, quercetin-3-(2''-xylosyl)rhamnoside (Bilia et al, 1996a) Licania tomentosa betulinic acid, licanolide, palmitoeic acid, oleanolic acid, stigmasterol, sitosterol, lupeol, tomentic acid, ursolic acid (Castilho & Kaplan, 2008) Licania carii myricetin-3-rutinoside, myricetin-3-glucoside, myricetin-3-(2''-xylosyl)rhamnoside, quercetin-3-(2''-xylosyl)rhamnoside, quercetin-3-galactoside, quercetin 3-glucoside, rutin, 2α-hydroxy ursolic acid, betulinic acid, maslinic acid. (Bilia et al, 1996b) Parinari campestris kaempferol-3-rutinoside, 15-oxozoapatlin-13α-yl-10'α,16'α-dihydroxy-9'α-methyl-20'norkauran-19'-oic acid γ-lactone-17'-oate, 13-hydroxy-15-oxozoapatlin, 10α,13α,16α,17-tetrahydroxy-9α-methyl-15-oxo-20-nor-kauran-19-oic acid γ-lactone, 2α,10α,13α,16α,17-pentahydroxy-9α-methyl-15-oxo-20-nor-kauran-19-oic acid (19,10)-lactone, 3α,10α,13α,16α,17-pentahydroxy-9α-methyl-15-oxo-20-nor-kauran-19-oic acid γ-lactone, 1β,16α,17-trihydroxy-ent-kaurane.…”

“…Quercetin flavonoids obtained from sheets of L. licaniaeflora and L. heteromorpha exhibit antioxidant activity (Braca et al, 2001a;Montoro et al, 2005). Licania carii, L. pittieri and L. pyrifolia are toxic against Biomphalaria glabrata Say, a mollusk involved in the reproductive cycle of Schistosoma mansoni Sambon (Bilia et al, 2000).…”

Constituintes químicos de licania tomentosa Benth. (Chrysobalanaceae)

“…O metabolismo especial dessa espécie é representado principalmente por flavonóides, cromonas e triterpenóides [17][18][19][20][21][22][23][24][25][26][27][28] .…”

“…O extrato de Licania tomentosa inibe a atividade do vírus herpes-simples 12 e os triterpenos isolados mostram-se citotóxicos 13,14 . Já os flavonóides de Licania licaniaeflora têm atividade antioxidante 15 , enquanto que o extrato de Licania michauxii induz a morte célular 16 .O metabolismo especial dessa espécie é representado principalmente por flavonóides, cromonas e triterpenóides [17][18][19][20][21][22][23][24][25][26][27][28] .O presente trabalho descreve o estudo químico de L. tomentosa, uma espécie vegetal da qual ainda não se conhece a composição química. O fracionamento dos extratos e das frações do extrato metanólico de L. tomentosa resultou no isolamento e identificação de ácido betulínico (1); de um triterpeno inédito, licanolídeo 29 (2); de ácido oleanólico (3); de uma mistura de estigmasterol (4) e sitosterol (5); de lupeol (6); de uma mistura de ácido tormêntico (7), ácido betulínico e ácido ursólico (8) e dois ácido graxos: ácido palmitoléico e hexadecanóico (Figura 1).…”