Tris‐Stabilized MoS₂ Nanosheets with Robust Dispersibility and Facile Surface Functionalization

Abstract

Here, tris(hydroxymethyl)aminomethane (i.e., Tris) is reported to be an effective protecting agent to stabilize 2D nanomaterials in water for various enhanced applications. As demonstrated, molybdenum sulfide (MoS2) nanosheets are first exfoliated from MoS2 bulk under a low‐energy sonication in the assistance of protein bovine serum albumin (BSA), and then BSA molecules are replaced with Tris to stabilize the exfoliated MoS2 nanosheets. The Tris‐stabilized MoS2 nanosheets have a robust dispersibility to resist long‐term storage (e.g., 2.5 years), high temperature (e.g., 220 °C), and high speed centrifugation (e.g., 12 000 rpm). Furthermore, they also exhibit high biocompatibility and promising photothermal effect, which provide a better performance in photothermal therapy for inhibiting the growth of tumor. In addition, the surface Tris molecules readily introduce the grafting of polydopamine on MoS2 nanosheets to form a universal platform for coating of other functional polymers on nanosheets. Overall, this work not only brings more opportunities to exploit the outstanding applications of 2D nanomaterials, but also suggests a new and effective route to prepare the composite of nanosheets and functional polymers for their synergistic properties.

Functionalized MoS2-Based Nanomaterials for Cancer Phototherapy and Other Biomedical Applications

“…The MoS 2 -based nanomaterials usually adopt covalent − and noncovalent modification strategies for functionalization. − One covalent strategy is the sulfur-chemistry-mediated modification. MoS 2 NSs obtained by chemically exfoliation have profound defects and edges, because of the loss of atoms during the intense ultrasonication process.…”

NIR‐II Responsive Inorganic 2D Nanomaterials for Cancer Photothermal Therapy: Recent Advances and Future Challenges

“…PCT could provide higher efficacy for growth inhibition via the synergistic effects from local hyperthermia triggered by light and rapid drug release compared with limitation of local treatment of PTT, which is beneficial for clinic translation. [123,336,337] Synergistic chemotherapy and photothermal therapy can further enhance the cancer therapeutic effect based on 2D materials because of their excellent photothermal properties and large specific surface area. [338][339][340][341] Doxorubicin (DOX) is the most frequently used chemotherapeutic drugs for cancer treatment.…”

2D nanosheet enabled thin film nanocomposite membranes for freshwater production – a review

“…14 To tackle the compatibility and stability factors, several additional studies were conducted to prepare functionalized MoS 2 nanosheets. 79,[81][82][83] Accordingly, high efficiency polyphenol assisted liquid exfoliation was used as a green method to produce layered MoS 2 nanosheets with tannic acid (TA-MoS 2 ). 83 Due to their improved stability and compatibility, TA-MoS 2 nanosheets were successfully incorporated into the polyamide layer, forming a TFN NF membrane with superior performance.…”