Triplet pregnancy with a coexisting complete hydatidiform mole of monospermic origin in a spontaneous conception

Rajesh, U; Cohn, M.; Foskett, Marianne; Fisher, Rosemary A.; Zaki, D.

doi:10.1111/j.1471-0528.2000.tb11663.x

Cited by 11 publications

(10 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Including this report, 14 cases of triplet or quadruplet pregnancy with a complete hydatidiform mole have been reported as shown in Table 2 1–13 . Among them, 11 cases (79%) were treated with clomiphene citrate or hMG for infertility or ovarian dysfunction.…”

Section: Discussionmentioning

confidence: 96%

“…A complete hydatidiform mole (CHM) with two or more coexisting fetuses (CHM‐TCF) is an extremely rare clinical condition. To date, only 13 cases have been reported 1–13 . Among them, 10 cases (77%) were identified as a complication of therapy for infertility such as an ovulation induction using clomiphene citrate and/or hMG‐hCG, 1–3,5 , 7,9 , 10,12 gamete intra‐fallopian transfer (GIFT) 4 and in vitro fertilization–embryo transfer (IVF‐ET) 2 .…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Complete hydatidiform mole in a triplet pregnancy coexisting two viable fetuses: Case report and review of the literature

Takagi

Unno

Hyodo

et al. 2003

J of Obstet and Gynaecol

View full text Add to dashboard Cite

We report a rare case of a complete hydatidiform mole with two or more coexisting fetuses where both infants survived without complications. A male infant weighing 1258 g and a female infant weighing 880 g were delivered without complications and discharged 95 days after the birth. The analysis of DNA microsatellite polymorphisms indicated that the mole was of paternal origin and probably homozygous. The mother suffered from multiple pulmonary metastasis of the hydatidiform mole which was detected 3 days after the surgery and was successfully treated with methotrexate. A complete hydatidiform mole with two or more coexisting fetuses produces a dilemma between immediate termination and pregnancy continuation. Although the present case resulted in a favorable outcome, a review of the 14 reported cases suggests that the high fetal loss rate (90%) must be a consideration in the decision regarding management of such a pregnancy.

show abstract

Section: Discussionmentioning

confidence: 96%

Section: Introductionmentioning

confidence: 99%

Complete hydatidiform mole in a triplet pregnancy coexisting two viable fetuses: Case report and review of the literature

Takagi

Unno

Hyodo

et al. 2003

J of Obstet and Gynaecol

View full text Add to dashboard Cite

show abstract

“…Triplet pregnancy with a coexisting mole is extremely rare 2–8 . Multiple conceptions involving hydatidiform mole with two or more fetuses are extremely rare but are likely to occur more frequently with the increasing number of multiple births in couples undergoing treatment for infertility 5 …”

Section: Discussionmentioning

confidence: 99%

“…Yet this is likely to more frequently occur with the increasing number of multiple births due to couples undergoing treatment for infertility. There have been several reports of a triplet pregnancy with a complete hydatidiform mole coexisting with two fetuses (CHMCF) 2–8 . However, to our knowledge, there was no report of triplet pregnancy with partial hydatidiform mole and a coexistent fetus (PHMCF).…”

Section: Introductionmentioning

confidence: 88%

Triplet pregnancy with partial hydatidiform mole coexisting with two fetuses: A case report

Kim¹,

Kim²,

Kim³

et al. 2008

J of Obstet and Gynaecol

View full text Add to dashboard Cite

Hydatidiform mole with a coexistent fetus is rare, but this condition has recently shown an increased incidence because of assisted reproduction technology. Herein, we report on a case of triplet pregnancy with a partial hydatidiform mole coexisting with two fetuses. It was diagnosed by p57(kip2) immunohistochemical staining which is helpful in determining histologically equivocal cases. After termination of pregnancy, the patient was diagnosed with persistent gestational trophoblastic disease. Six courses of methotrexate chemotherapy were performed. Her beta-human chorionic gonadotrophin titers then fell to a normal level.

show abstract

“…Amr et al (13) Clomiphene + hCG 30 1 None 9. Rajesh et al (14) None 24 0 Vaginal bleeding 10. Malhotra et al (15) None 21 0 Vaginal bleeding 11.…”

Section: Maternal Complicationsmentioning

confidence: 99%

Complete Hydatidiform Mole in a Triplet Pregnancy With Coexisting Two Live Foetuses- A Case Report and Review of Literature

U¹,

Kanchana²,

Revathy³

2017

jemds

View full text Add to dashboard Cite

BACKGROUND Hydatidiform mole with coexisting twin foetus is an infrequent condition that has been reported in a limited number of cases. (1-4) Only 12 cases of triplet pregnancy with complete mole and two foetuses following ovulation induction, Assisted Reproductive Techniques (ART) and spontaneous conceptions are reported. (1) We describe a case of complete hydatidiform mole with coexisting viable two foetuses following ovulation induction. A 35-year-old lady was pregnant following ovulation induction with clomiphene citrate. A triplet pregnancy with two live foetuses and a complete mole was delivered at 32 weeks of gestation. The antenatal period was uneventful. Continuation of pregnancy as long as maternal complications are absent or controllable can be a safe and rewarding effort in managing the patient.

show abstract

Triplet pregnancy with a coexisting complete hydatidiform mole of monospermic origin in a spontaneous conception

Cited by 11 publications

References 14 publications

Complete hydatidiform mole in a triplet pregnancy coexisting two viable fetuses: Case report and review of the literature

Complete hydatidiform mole in a triplet pregnancy coexisting two viable fetuses: Case report and review of the literature

Triplet pregnancy with partial hydatidiform mole coexisting with two fetuses: A case report

Complete Hydatidiform Mole in a Triplet Pregnancy With Coexisting Two Live Foetuses- A Case Report and Review of Literature

Contact Info

Product

Resources

About