BACKGROUND Androgen secreting ovarian tumours represents less than 5% of all ovarian neoplasms. Hyperandrogenism results in development of acne, hirsutism, androgenic alopecia, menstrual irregularities & virilisation or masculinization. The objective of this study is to look for incidence of virilisation in sex cord stromal tumours and discussion regarding various causes of hyperandrogenism. MATERIALS AND METHODS A retrospective descriptive study of virilising tumours of ovary was conducted in a tertiary care gynaecological centre at Institute of obstetrics and Gynaecology, Chennai for a period of 5 years from February 2012 to February 2017. 4 cases of sex cord stromal tumours presented with signs of virilisation. RESULTS A total of 592 ovarian malignancies were identified over a period of 5 yrs. out of which 36 cases were diagnosed as sex cord stromal tumours (6.08%). The most common age group affected are between 41 to 50 yrs. with median age of 45 yrs. Right sided ovary (58%) is more commonly involved than left sided (42%) ovary. Most of the tumours were solid in appearance with average size ranging between 6 cm-10 cm. The most common symptom is abdominal mass (64%) with 4 cases presented with history of virilisation (11%). CONCLUSION Based on present study it may be concluded that patients with symptoms of virilisation require detailed clinical history, physical examination for signs, laboratory investigations & imaging to exclude causes other than ovarian neoplasm.
BACKGROUND Hydatidiform mole with coexisting twin foetus is an infrequent condition that has been reported in a limited number of cases. (1-4) Only 12 cases of triplet pregnancy with complete mole and two foetuses following ovulation induction, Assisted Reproductive Techniques (ART) and spontaneous conceptions are reported. (1) We describe a case of complete hydatidiform mole with coexisting viable two foetuses following ovulation induction. A 35-year-old lady was pregnant following ovulation induction with clomiphene citrate. A triplet pregnancy with two live foetuses and a complete mole was delivered at 32 weeks of gestation. The antenatal period was uneventful. Continuation of pregnancy as long as maternal complications are absent or controllable can be a safe and rewarding effort in managing the patient.
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