Trimester-specific reference ranges for thyroid function tests in South Indian women

Rani, K Sandhya; Tirupati, Sunanda; Sarathi, Vijaya; Kumar, Krishna

doi:10.4103/trp.trp_24_18

Cited by 2 publications

(3 citation statements)

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“…Table (3), this is difference due to inclusion and exclusion criteria or due to different assay methods. Our results were in agreement with results of study done in India with mean±SD 1.11±0.57 1 ST Tri,1.58±0.61 2 nd Tri and 1.63±0.64 3 rd Tri Rani etal.,2018 [ 11 ] .…”

Section: Discussionmentioning

confidence: 99%

“…Each of which used for the following measurements 1.TSH utilizing Access 2(Beckman Coulter) NHANES, USA utilizing electrochemi-luminescence (ECL)technique, with the limit of detection 0.005 mIU/Measuring range ( 0.01-50.0 )mIU/L reference range of the kit used (0.38-5.33)mIU/L . [11] 2.Anti -TPO was measured on the Algeria Orgentic using the enzyme -linked immunosorbent assay ̏ ELISA ̋ .Sensitivity was determined to be 5 IU/ml ,measuring range was 0-3000 IU/ml and cut-off 75 IU/ml. [12]Negative less than 50 IU/ml, Borderline50-75IU/ml, and the Positive was morethan75IU/ml.…”

Section: 2methodsmentioning

confidence: 99%

“…The upper limits of TSH reported in the current study are 2.79 mIU/L for the 1 st Tri and 3.39 mIU/L for the 3rd Tri are closer to that suggested by American Thyroid Association ( ATA ) guidelines 2011, that recommended 0.1 -2.5 , 0.2 -3.0 and 0.3 -3 mIU / L for 1st Tri ,2 nd Tri and 3 rd Tri respectively [20] . We compared our study results to those reported in different countries (India [11] , China [21], Australia [22] and Netherlands [8]) using Beckman Access or DxI and 2.5% -97.5% percentiles of TSH , Table( 4) Shows that upper limit of TSH in the 1 st Tri in all studies were around 3.0 ( mIU / L ) except study 2 as well as the lower limit of TSH in the 2 nd Tri were around 0.4 except that reported in study 3 . Although all these five studies were used Beckman as instrument for measuring TSH still this difference can explain different ethnicity and geographical factors.…”

Section: Table 3: Comparison Of Mean Of Thyroid Stimulating Hormone B...mentioning

confidence: 99%

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Trimester-Specific Thyrotropin Hormone Reference Levels in Mosul City, Iraq

Naif

Allawi

2021

Egypt. J. Chem.

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Thyroid disorders during pregnancy is widespread and it is linked with adverse obstetric outcomes. Serum thyroidstimulating hormone ( TSH ), also known as thyrotropin hormone is optimal indicator for monitoring and evaluating thyroid function. There are significant changes in thyroid physiology during gestation. Thus different TSH levels are recorded in pregnant women in different countries, Therefore. the aim of current study : To determine trimester (Tri) specific levels of TSH in the apparently healthy pregnant women in Mosul city. A crosssectional study was conducted at Hospitals, Primary Health Centers and Outpatient clinics in Mosul city and collected from December 2020 to April 2021. Total enrolled pregnant women were 200 of age 18 -32 years, 80 of them were excluded from study for meeting one or more of exclusion criteria . The remaining of 120 women were included in study, 40 women were assigned to each Tri. Thyrotropin and antithyroid peroxidase were measured for participants. The study results showed TSH levels increased over the Tri with very significantly higher TSH levels in the third in compared with first Tri. Accordingly the reference levels of TSH 0.33-2.79 mIU/L, 0.43-3.88 mIU/L, 0.57-3.39 mIU/L for the first, second and third Tri respectively. Our conclusion that the upper limit of TSH reference ranges for pregnant women in the first and second Tri was closer to that suggested by the American Thyroid Association( ATA) guidelines 2011 and some other countries.

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Section: Discussionmentioning

confidence: 99%

Section: 2methodsmentioning

confidence: 99%

Section: Table 3: Comparison Of Mean Of Thyroid Stimulating Hormone B...mentioning

confidence: 99%

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Trimester-Specific Thyrotropin Hormone Reference Levels in Mosul City, Iraq

Naif

Allawi

2021

Egypt. J. Chem.

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Thyroid disorders in pregnancy

Rajput

Bajaj

Ghosh

et al. 2021

Thyroid Research and Practice

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Thyroid disease is the second most common endocrine disorder encountered in pregnant women with substantial maternal and fetal implications. Therefore, assessing thyroid status during pregnancy is essential for initiating treatment in newly diagnosed individuals and adjusting doses for those already under treatment. To initiate proper and timely treatment evidence-based recommendations are required for clinical decisionmaking in managing thyroid disorders in pregnant and postpartum women. Keeping this in mind, task force consisted of experts in the fields of endocrinology and thyroid disease was constituted and various published data and guidelines were explored to address screening, diagnosis, and management of hypothyroidism, thyrotoxicosis, GD, thyroid nodules, and post-partum thyroiditis and their related complications during pregnancy. This document provides much-required insights and useful, practical, and accurate guidance that aids a practicing clinician.

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Trimester-specific reference ranges for thyroid function tests in South Indian women

Cited by 2 publications

References 1 publication

Trimester-Specific Thyrotropin Hormone Reference Levels in Mosul City, Iraq

Trimester-Specific Thyrotropin Hormone Reference Levels in Mosul City, Iraq

Thyroid disorders in pregnancy

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