Trigeminal and Taste Sensations of the Tongue After Middle Ear Surgery

Sakaguchi, Akiko; Nin, Tomomi; Katsura, Hirokazu; Mishiro, Yasuo; Sakagami, Masafumi

doi:10.1097/mao.0b013e3182979278

Cited by 11 publications

(57 citation statements)

References 9 publications

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“…Sakaguchi et al [2] reported that patients with an injured CTN show significant threshold differences in an electrostimulator test between the operated and nonoperated sides of the tongue. One report showed that the CTN includes somatosensory afferents [18].…”

Section: Discussionmentioning

confidence: 98%

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Changes in transient receptor potential channels in the rat geniculate ganglion after chorda tympani nerve injury

Tatsumi

Katsura²,

Kobayashi³

et al. 2015

NeuroReport

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We reported differential expression of the transient receptor potential vanilloid 1 (TRPV1), the transient receptor potential ankyrin 1 (TRPA1), and the (TRPM8) in the geniculate ganglions (GGs) of naive rats. In medical practice, the chorda tympani nerve (CTN) is injured in some patients during middle-ear surgery, and results in tongue numbness and taste disorder. We investigated changes in the expression of these receptors in GGs after CTN injury. In naive-rat GGs, 11.4, 11.8, and 0.5% of neurons were found to express the TRPV1, the TRPA1, the TRPM8, respectively. At 3 days after CTN injury, 5.2 and 4.0% of activating transcription factor 3-immunoreactive neurons, considered as injured neurons, were found to express the TRPV1 and the TRPA1, respectively. Among activating transcription factor 3-immunonegative neurons, considered as uninjured neurons, 3.9 and 3.8% were found to express the TRPV1 and the TRPA1, respectively. The TRPM8 was not detected in GGs after CTN injury. We found decreased mRNA levels of the TRPV1 and the TRPA1 in all neurons, as well as in uninjured neurons of ipsilateral GGs after CTN injury. CTN injury changes the gene expression in GGs and may have effects on the tongue.

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Section: Discussionmentioning

confidence: 98%

“…Tasting with the tongue depends on the CTN, and the tongue somatosensory function depends on the lingual nerve, which is the third branch of the trigeminal nerve. Patients with CTN injury sometimes complain of not only a taste disorder but also tongue numbness [2].…”

Section: Introductionmentioning

confidence: 99%

Changes in transient receptor potential channels in the rat geniculate ganglion after chorda tympani nerve injury

Tatsumi

Katsura²,

Kobayashi³

et al. 2015

NeuroReport

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“…There were 46 cases with preservation of the CTN and 13 cases with sectioning of the CTN. In addition, 106 adult patients were compared with the pediatric patients, and they were included in the previous study . Of the 106 cases, 44 had cholesteatoma; 34 had chronic otitis media; and 28 had noninflammatory middle ear disease.…”

Section: Methodsmentioning

confidence: 99%

“…There have been a few reports of the changes in lingual trigeminal sensitivity after middle ear surgery. They reported that somatosensory function deteriorated on the affected side after middle ear surgery . It is generally thought that pediatric patients complain of postoperative taste function less frequently than adult patients .…”

Section: Introductionmentioning

confidence: 99%

Earlier recovery of lingual dysfunction after middle ear surgery in pediatric versus adult patients

et al. 2019

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Objectives It is generally thought that the recovery of damaged chorda tympani nerve (CTN) function after middle ear surgery is different in pediatric patients from that in adult patients. The purpose of this study was to investigate the changes and the progress of taste and somatosensory functions of the tongue after middle ear surgery in pediatric patients compared with those of adult patients. Study Design Prospective study. Methods Fifty‐nine pediatric patients and 106 adult patients underwent middle ear surgery. Taste and somatosensory functions of the anterior tongue, the so‐called CTN functions, were assessed using electrogustometry (EGM), a 2‐point discriminator, an electrostimulator, and a questionnaire before and 2 weeks and 6 months after surgery. Results Two weeks after surgery, there was no significant difference in the incidence of dysgeusia and abnormal EGM thresholds between the patient groups. The incidence of tongue numbness was significantly lower in pediatric patients than in adult patients regardless of CTN manipulation. Although the lingual somatosensory thresholds of adult patients were significantly increased, those of pediatric patients were not increased. Six months after surgery, the incidences of dysgeusia and an abnormal EGM threshold were lower in pediatric patients than in adult patients. Tongue numbness disappeared, and the thresholds of lingual somatosensory tests returned to normal in most pediatric patients. Conclusion Not only taste function but also lingual somatosensory function was damaged after middle ear surgery even in pediatric patients. Pediatric patients complained of tongue numbness less frequently and showed earlier recovery than adult patients. Level of Evidence 2 Laryngoscope, 130:1016–1022, 2020

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“…Trigeminal nerve function on the tongue has been examined in a few previous reports using, for example, Semmes‐Weinstein sensory test (SW test), 2‐point discrimination, and capsaicin. Sakaguchi et al reported that postoperative thresholds in the CTN‐sectioned group and the manipulated group were significantly higher than the preoperative thresholds on the electrostimulator test and electrogustometry (EGM). They also noted that the electrostimulator was the most useful tool to objectively assess trigeminal nerve sensation, whereas the SW test had low sensitivity to assess sensory changes.…”

Section: Introductionmentioning

confidence: 98%

Change of somatosensory function of the tongue caused by chorda tympani nerve disorder after stapes surgery

et al. 2017

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Trigeminal and Taste Sensations of the Tongue After Middle Ear Surgery

Cited by 11 publications

References 9 publications

Changes in transient receptor potential channels in the rat geniculate ganglion after chorda tympani nerve injury

Changes in transient receptor potential channels in the rat geniculate ganglion after chorda tympani nerve injury

Earlier recovery of lingual dysfunction after middle ear surgery in pediatric versus adult patients

Change of somatosensory function of the tongue caused by chorda tympani nerve disorder after stapes surgery

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