1993
DOI: 10.1080/00150199308019934
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Trifluoromethylated pyranose derivatives as the chiral dopant for ferroelectric liquid crystals

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Cited by 21 publications
(1 citation statement)
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“…These special properties of fluorine have been exploited for the development of new and effective biochemical tools as well as agrochemical, medicinal, and therapeutic agents, particularly in the field of enzymatic inhibition . Particularly attractive are 2,2-difluoro-3-hydroxyacids, which are versatile intermediates for the preparation of a variety of bioactive materials, such as difluorinated gingerol, a potent inhibitor of prostaglandin biosynthesis, chiral 2,2-difluorocitrate as inhibitors of rat liver ATP citrate lyase and porcine heart aconitase or yeast mitochondria, difluorostatine peptides as potent and specific renin inhibitors, proteolysis inhibitors or ferroelectric liquid crystals, among others. Although a number of procedures have been developed to prepare 2,2-difluoro-3-hydroxyacids, , new, efficient methods of preparation from cheap, easily available fluorinated materials are always desirable.…”
mentioning
confidence: 99%
“…These special properties of fluorine have been exploited for the development of new and effective biochemical tools as well as agrochemical, medicinal, and therapeutic agents, particularly in the field of enzymatic inhibition . Particularly attractive are 2,2-difluoro-3-hydroxyacids, which are versatile intermediates for the preparation of a variety of bioactive materials, such as difluorinated gingerol, a potent inhibitor of prostaglandin biosynthesis, chiral 2,2-difluorocitrate as inhibitors of rat liver ATP citrate lyase and porcine heart aconitase or yeast mitochondria, difluorostatine peptides as potent and specific renin inhibitors, proteolysis inhibitors or ferroelectric liquid crystals, among others. Although a number of procedures have been developed to prepare 2,2-difluoro-3-hydroxyacids, , new, efficient methods of preparation from cheap, easily available fluorinated materials are always desirable.…”
mentioning
confidence: 99%