Tricuspid endocarditis causing massive pulmonary embolism in a non-addicted patient without any underlying cardiac disease

Abstract

We report a case of septic right superior ophthalmic vein thrombosis complicated by left sphenoid sinusitis with methicillin-sensitive Staphylococcus aureus (MSSA). Early recognition by clinical symptoms, and computed tonography (CT) and magnetic resolution image (MRI) of the head and sinus is needed for prompt surgical drainage of the sinus and appropriate antimicrobial therapy. The use of steroids and anticoagulation for this condition is still debated.

Impact of superior ophthalmic vein thrombosis: a case series and literature review

“…In literature, paranasal sinusitis is the most common cause of septic SOVT. 13,[27][28][29][30][31][32][33] In our series, the majority of cases were aseptic (77.8%). This corresponds to the literature, where we also found more aseptic SOVT (66.7%).…”

Concurrent Atlantoaxial Septic Arthritis and Septic Thrombosis of the Ophthalmic Vein due to Staphylococcus aureus: A Case Report and Review of the Literature

“…Septic thrombosis of the superior ophthalmic vein without involvement of cavernous sinus is also rare. The most common feature described in previously reported cases of septic superior ophthalmic vein thrombosis was limited extraocular movements (n = 13) [9–21]. The abducens nerve, or cranial nerve VI, courses through the central part of the superior orbital fissure, running lateral to the superior ophthalmic vein, and thus thrombosis of this vein can lead to direct compression of the abducens nerve, which innervates the lateral rectus muscle [22].…”

Daptomycin cure after cefazolin treatment failure of Methicillin-sensitive Staphylococcus aureus (MSSA) tricuspid valve acute bacterial endocarditis from a peripherally inserted central catheter (PICC) line

“…We presume cefazolin failure in this case was probably the result of inadequate penetration and sterilization of the large vegetation (1 ϫ 2 cm). [24][25][26][27][28][29][30][31][32][33][34][35][36][37][38][39] There are many bactericidal antibiotics that are effective against MSSA ABE. Because the patient had MSSA ABE and the strain was sensitive to cefazolin, cefazolin was a reasonable initial choice to treat the TV MSSA ABE.…”

“…1,2,22,23 The causes of treatment failure in staphylococcal ABE include selecting a drug with inadequate activity against S. aureus, inadequate dose and duration of therapy, very high protein binding, metastatic septic complications, or inability to penetrate or sterilize the vegetation. [24][25][26][27][28][29][30][31][32][33][34][35][36][37][38][39] In patients with ABE, the size of the vegetation correlates with embolic potential, that is, the larger the vegetation the more likely it is to embolize. Effective therapy for ABE requires elimination of organisms from the bloodstream and sterilization of the vegetation.…”