Triclosan-induced transcriptional and biochemical alterations in the freshwater green algae Chlamydomonas reinhardtii

Pan, Chang-Gui; Peng, Feng-Jiao; Shi, Wen; Hu, Li; Wei, Xiao; Ying, Guang Guo

doi:10.1016/j.ecoenv.2017.10.011

Cited by 56 publications

(25 citation statements)

References 57 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…TCS exposure caused alterations in Cat , Sod , Gpx1 , Gpx2 , Gsta , Hsp90bb , Hsp90ba , and Hsc70a genes in rainbow trout Oncorhynchus mykiss [124]. Although in one report TCS failed to elicit oxidative stress in the green algae Chlamydomonas reinhardtii [125], another report detected ROS formation following TCS exposure [90], which was also most recently confirmed by significantly increased MDA, downregulated Gpx , and upregulated Sod expression [126].…”

Section: Oxidative Stressmentioning

confidence: 98%

Triclosan: An Update on Biochemical and Molecular Mechanisms

Alfhili

Lee

2019

Oxidative Medicine and Cellular Longevity

100

View full text Add to dashboard Cite

Triclosan (TCS) is a synthetic, chlorinated phenolic antimicrobial agent commonly used in commercial and healthcare products. Items made with TCS include soaps, deodorants, shampoos, cosmetics, textiles, plastics, surgical sutures, and prosthetics. A wealth of information obtained from in vitro and in vivo studies has demonstrated the therapeutic effects of TCS, particularly against inflammatory skin conditions. Nevertheless, extensive investigations on the molecular aspects of TCS action have identified numerous adversaries associated with the disinfectant including oxidative injury and influence of physiological lifespan and longevity. This review presents a summary of the biochemical alterations pertaining to TCS exposure, with special emphasis on the diverse molecular pathways responsive to TCS that have been elucidated during the present decade.

show abstract

Section: Oxidative Stressmentioning

confidence: 98%

Triclosan: An Update on Biochemical and Molecular Mechanisms

Alfhili

Lee

2019

Oxidative Medicine and Cellular Longevity

100

View full text Add to dashboard Cite

show abstract

“…Triclosan (TCS) was inhibitory against growth of numerous green microalgae (Table 10, Table S2). Triclosan caused inhibition/toxicity to Pseudokirchneriella subcapitata/Raphidocelis subcapitata/Selenastrum capricornutum growth [81,157,190,191,192,193], different Chlamydomonas strains [151,194,195], Dunaliella strains [139,151], Tetraselmis suecica [196], different Scenedesmus / Desmodesmus strains [151,197,198,199] and Chlorella strains [151,199,200]. Inhibitory/toxicity effects of TCS on growth of the diatoms Skeletonema pseudocostatum [153], Navicula sp.…”

Section: Inhibitory Effect Of Pharmaceuticals and Personal Care Prmentioning

confidence: 99%

“…Lipid peroxidation occurs during cellular oxidative stress, leading to the generation of malondialdehyde (MDA), a peroxidation product of fatty acids. Table 12 shows that PHRs such as amoxicillin [219,220,221], ciprofloxacin [108,222], enrofloxacin [95,97], norfloxacin [99,219], levofloxacin [102], tetracycline [57], doxycycline [71], chlortetracycline [64], florfenicol [46], thiamphenicol [46], erythromycin [113,222], spiramycin [220], sulfamethoxazole [222], carbamazepine [170] and ethinylestradiol [179] and PCPs such as triclosan [194,195] can cause increases in MDA content in different microalgal strains. The general pattern in mentioned reports is that MDA content increases up to the maximal concentration with the increase in PHRs/PCPs concentrations in the media.…”

Section: Effect Of Pharmaceuticals and Personal Care Products On Mmentioning

confidence: 99%

Effect of PHRs and PCPs on Microalgal Growth, Metabolism and Microalgae-Based Bioremediation Processes: A Review

Miazek

Brożek-Płuska

2019

IJMS

View full text Add to dashboard Cite

In this review, the effect of pharmaceuticals (PHRs) and personal care products (PCPs) on microalgal growth and metabolism is reported. Concentrations of various PHRs and PCPs that cause inhibition and toxicity to growths of different microalgal strains are summarized and compared. The effect of PHRs and PCPs on microalgal metabolism (oxidative stress, enzyme activity, pigments, proteins, lipids, carbohydrates, toxins), as well as on the cellular morphology, is discussed. Literature data concerning the removal of PHRs and PCPs from wastewaters by living microalgal cultures, with the emphasis on microalgal growth, are gathered and discussed. The potential of simultaneously bioremediating PHRs/PCPs-containing wastewaters and cultivating microalgae for biomass production in a single process is considered. In the light of reviewed data, the feasibility of post-bioremediation microalgal biomass is discussed in terms of its contamination, biosafety and further usage for production of value-added biomolecules (pigments, lipids, proteins) and biomass as a whole.

show abstract

“…Yurkov et al ( 1996 ) observed that some Erythrobacter displayed resistance to the reactive oxygen species (ROS)-generating compound tellurite, and TCS is well known for its ROS-mediated toxic effects in various organisms (e.g. Li et al 2018 ; Pan et al 2018 ). We therefore hypothesize that TCS exposure selects for Erythrobacteraceae because of their superior ability to handle TCS-induced oxidative stress.…”

Section: Resultsmentioning

confidence: 99%

Triclosan changes community composition and selects for specific bacterial taxa in marine periphyton biofilms in low nanomolar concentrations

et al. 2020

View full text Add to dashboard Cite

The antibacterial agent Triclosan (TCS) is a ubiquitous environmental contaminant due to its widespread use. Sensitivity to TCS varies substantially among eu-and pro-karyotic species and its risk for the marine environment remains to be better elucidated. In particular, the effects that TCS causes on marine microbial communities are largely unknown. In this study we therefore used 16S amplicon rDNA sequencing to investigate TCS effects on the bacterial composition in marine periphyton communities that developed under long-term exposure to different TCS concentrations. Exposure to TCS resulted in clear changes in bacterial composition already at concentrations of 1 to 3.16 nM. We conclude that TCS affects the structure of the bacterial part of periphyton communities at concentrations that actually occur in the marine environment. Sensitive taxa, whose abundance decreased significantly with increasing TCS concentrations, include the Rhodobiaceae and Rhodobacteraceae families of Alphaproteobacteria, and unidentified members of the Candidate division Parcubacteria. Tolerant taxa, whose abundance increased significantly with higher TCS concentrations, include the families Erythrobacteraceae (Alphaproteobacteria), Flavobacteriaceae (Bacteroidetes), Bdellovibrionaceae (Deltaproteobacteria), several families of Gammaproteobacteria, and members of the Candidate phylum Gracilibacteria. Our results demonstrate the variability of TCS sensitivity among bacteria, and that TCS can change marine bacterial composition at concentrations that have been detected in the marine environment.

show abstract

Triclosan-induced transcriptional and biochemical alterations in the freshwater green algae Chlamydomonas reinhardtii

Cited by 56 publications

References 57 publications

Triclosan: An Update on Biochemical and Molecular Mechanisms

Triclosan: An Update on Biochemical and Molecular Mechanisms

Effect of PHRs and PCPs on Microalgal Growth, Metabolism and Microalgae-Based Bioremediation Processes: A Review

Triclosan changes community composition and selects for specific bacterial taxa in marine periphyton biofilms in low nanomolar concentrations

Contact Info

Product

Resources

About