Trichotillomania Associated With Aripiprazole

Çıldır, Deniz Argüz; Kalyoncu, Tuğba

doi:10.1097/jcp.0000000000000821

Cited by 4 publications

(3 citation statements)

References 16 publications

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“…Studies strongly support the role of serotonin and dopamine dysfunction in the pathophysiology of TTM [5]. A possible association between TTM and psychiatric medications, such as aripiprazole [6] and fluoxetine [7], has been reported. There are case reports of TTM associated with dopaminergic agents like stimulants [8][9][10][11].…”

Section: Introductionmentioning

confidence: 83%

“…The use of antipsychotic agents that block dopaminergic D2 receptors has been effective in the management of TTM patients [19]. But there is a case of TTM arising after receiving treatment with aripiprazole (5 mg/day) in a 16-year-old male patient with ADHD and conduct disorder [6]. The authors stated that aripiprazole may also act as an agonist rather than an antagonist at dopamine receptors of low doses [6].…”

Section: Discussionmentioning

confidence: 99%

“…But there is a case of TTM arising after receiving treatment with aripiprazole (5 mg/day) in a 16-year-old male patient with ADHD and conduct disorder [6]. The authors stated that aripiprazole may also act as an agonist rather than an antagonist at dopamine receptors of low doses [6]. Kara et al reported that TTM developed in a 9-year-old male with 12 h of extended-release methylphenidate [11].…”

Section: Discussionmentioning

confidence: 99%

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Probable emergence of symptoms of trichotillomania by atomoxetine: a case report

Ayaydın

2018

Psychiatry and Clinical Psychopharmacology

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Attention-deficit hyperactivity disorder (ADHD) is a common neurodevelopmental disorder in childhood. Atomoxetine is the first nonpsychostimulant agent approved by the Food and Drug Administration for the treatment of ADHD. Trichotillomania (TTM) is an obsessivecompulsive and related disorder characterized by a long-term urge that results in the pulling out of one's hair from any part of his/her body. Studies have implicated dopaminergic and serotonergic dysfunction in the aetiology of TTM. We report a male patient with ADHD developing of symptoms of TTM following atomoxetine use. Atomoxetine indirectly affects dopamine levels in the mesolimbic dopamine system, similarly to methylphenidate/ amphetamine, and can thus lead to hair pulling behaviour. Further studies concerning the potential adverse effects of atomoxetine, such as the development of TTM, are now needed.

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