Trichoscopic findings of discoid lupus erythematosus alopecia: A cross-sectional study

Gómez-Quispe, Heidy; Heras-Alonso, M.E. de las; Lobato‐Berezo, Alejandro; Velasco‐Tamariz, Virginia; Pindado‐­Ortega, Cristina; Moreno‐Arrones, Óscar M.; Vañó‐Galván, Sergio; Saceda‐Corralo, David

doi:10.1016/j.jaad.2020.05.144

Cited by 13 publications

(53 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Dermoscopic features of follicular openings in scalp and nonscalp DLE were reported in 17 4,7,[9][10][11][12][13][14][15][16][17][18][19][20][21] and nine papers, [21][22][23][24][25][26][27][28][29] respectively (Table 2). In scalp DLE, the most common findings were follicular keratotic plugs (mean frequency 47%), followed by absent follicular ostia (45.8%), fibrotic white dots (33.7%), yellow dots (21.1%), black dots (17.5%), and red dots (13.3%).…”

Section: Follicular Openingsmentioning

confidence: 99%

“…16 Nevertheless, their presence has been detected in long-lasting lesions, as well. 20,21 Follicular plugs were observed in scalp DLE in a total number of 78/166 lesions (47%). [5][6][7][9][10][11][13][14][15][16][18][19][20][21] They were also the most common finding in nonscalp DLE plaques (86/129 lesions; 66.7%).…”

Section: Follicular Openingsmentioning

confidence: 99%

“…Their presence in scalp DLE was reported in a total of 29/166 (17.5%) lesions. 5,[14][15][16]20 Figure 1 The PRISMA flowchart of database search and literature selection Follicular red dots. Follicular red dots in scalp DLE were described for the first time by Tosti et al 35 in 2009.…”

Section: Follicular Openingsmentioning

confidence: 99%

“…Apart from the aforementioned study, this dermoscopic feature was noted only in one, recently published, study, in which it was found to be present in 4/55 (7.3%) patches of scalp DLE. 20 One of the possible explanations may be the fact, that a large number of studies concerning scalp DLE were carried out among dark-skinned patients, in whom thin vessels may not be easily visible.…”

Section: Follicular Openingsmentioning

confidence: 99%

See 3 more Smart Citations

Dermoscopy of discoid lupus erythematosus – a systematic review of the literature

Żychowska

2020

Int J Dermatology

View full text Add to dashboard Cite

Background Discoid lupus erythematosus (DLE) may lead to disfiguring scarring and permanent hair loss. Dermoscopy may serve as a noninvasive tool useful in the preliminary diagnosis of hair loss and inflammatory skin diseases. The aim of the paper was to summarize and analyze the dermoscopic features of DLE lesions in various anatomical locations.Methods A systematic review of PubMed, Scopus and Web of Science was performed using the search terms: 'lupus' OR 'discoid lupus' OR 'cutaneous lupus' combined with 'dermoscopy' OR 'dermatoscopy' OR 'videodermoscopy' OR 'videodermatoscopy' OR 'trichoscopy' OR 'mucoscopy' OR 'onychoscopy'.Results About 29 out of 318 initially identified papers were included in the analysis. In scalp DLE (n = 166), the most common findings were: white structureless areas (62%), arborizing vessels (57.8%), white scales (54.2%), follicular keratotic plugs (47%), absent follicular openings (45.8%), perifollicular scaling (43.9%), pink-white background (40.4%), speckled brown pigmentation (38%), and fibrotic white dots (33.7%). In non-scalp DLE (n = 129), the most frequent features were: follicular keratotic plugs (66.7%), white perifollicular halo (65.9%), white scale (39.5%), speckled brown pigmentation (38.8%), white structureless areas (37.2%), and arborizing vessels (34.9%). There are scarce data in the literature on dermoscopic findings in labial (n = 8), mucosal (n = 3) and ungual DLE (n = 1).Conclusions DLE is characterized by a wide variety of dermoscopic findings with variable frequencies depending on the location of the lesions. Nevertheless, further studies are needed in order to reliably assess frequencies, correlation with disease stage and significance of individual dermoscopic features.

show abstract

Section: Follicular Openingsmentioning

confidence: 99%

Section: Follicular Openingsmentioning

confidence: 99%

Section: Follicular Openingsmentioning

confidence: 99%

Section: Follicular Openingsmentioning

confidence: 99%

See 2 more Smart Citations

Dermoscopy of discoid lupus erythematosus – a systematic review of the literature

Żychowska

2020

Int J Dermatology

View full text Add to dashboard Cite

show abstract

“…This no invasive diagnostic methodic is able to provide any differential diagnosis according to the extreme clinical variability of CLEs often mimicking chronic eczema, toxic skin reactions, sarcoidosis, light eruptions, lymphomas, cutaneous squamocellular-carcinoma, basocellular-carcinoma, pseudo lymphomas and post-inflammatory hyperpigmentation, granuloma faciale. 7–9…”

Section: Introductionmentioning

confidence: 99%

The combined role of clinical, reflectance confocal microscopy and dermoscopy applied to chronic discoid cutaneous lupus and subacutus lupus erythematosus: A case series and literature review

Mazzilli

Vollono

Diluvio

et al. 2020

Lupus

View full text Add to dashboard Cite

Main subtypes of cutaneous lupus erythematosus are represented by acute, subacute cutaneous, intermittent and chronic cutaneous lupus erythematosus. Discoid lupus erythematosus represents the most common phenotype of chronic cutaneous lupus erythematosus. The spectrum of clinical manifestations mirrors that of several and distinct histopathological features. Such variability among different CLE subtypes is also observed at dermoscopy. Dermoscopy is nowadays considered an additional valuable method for skin lesions assessment in general dermatology, following and completing the well-known clinical diagnostic steps, such as medical history and clinical examination. In vivo reflectance confocal microscopy (RCM) is a non-invasive imaging tool able to assess the epidermis and upper dermis producing high resolution (horizontal ∼1.25 μm, vertical ∼5 μm), en face tissue sections used for melanocytic and inflammatory evaluation. In this study, we reported dermoscopic and RCM features about 9 patients affected by subacute and chronic lupus erythematosus retrospectively analyzed.

show abstract

Chronic Cutaneous Lupus Erythematosus in a White Population: Dermoscopic Characteristics by Clinical Subtype, Lesion Location and Disease Duration

Żychowska

Reich

2022

Dermatol Ther (Heidelb)

View full text Add to dashboard Cite

Introduction Chronic cutaneous lupus erythematosus (CCLE) comprises three major clinical variants: discoid lupus erythematosus (DLE), chilblain lupus erythematosus (CHLE), and lupus erythematosus profundus, also referred to as lupus erythematosus panniculitis (LEP). The aim of the current study was to systematically describe the dermoscopic features of CCLE in Polish patients with Fitzpatrick skin phototypes I–III. Methods The videodermoscopic images from patients with various clinical variants of CCLE (DLE, CHLE and LEP) were reviewed. Predefined parameters for dermoscopic evaluation in general dermatology were used to describe the findings in lesions located beyond the scalp. In the analysis of trichoscopic findings in lesions located on the scalp, dermoscopic features of follicular openings, hair shafts, the perifollicular surface, the interfollicular surface and vessel morphology were considered. Based on personal experience, several additional dermoscopic and trichoscopic characteristics were included in the analysis. Results A total of 85 lesions from 26 patients (16 women and 10 men; mean age 40.8 ± 11.2 years) were assessed. DLE on glabrous skin showed polymorphous vessels (89.1%), pink-red background (70.9%), follicular plugs (67.3%) and white scaling (58.2%), while scalp DLE was characterized by polymorphous vessels (83.3%), yellow dots (66.7%), follicular plugs (55.6%) and a reduced number of follicles (55.6%). Labial DLE ( n = 2) showed linear branched and linear curved vessels, white structureless areas, red structureless (hemorrhagic) areas and red dots/globules. White scaling (61.1% vs. 34.1%; p = 0.042), gray-brown dots/globules (44.4% vs. 12.2%; p = 0.015) and peripheral pigmentation (100.0% vs. 46.2%; p = 0.036) were significantly more common in long-lasting (> 1 year) DLE lesions. CHLE ( n = 5) presented with polymorphous vessels, white scales, pink-red background, red structureless areas and red dots/globules. LEP showed polymorphous vessels, white-yellow scales, follicular plugs, white structureless areas and red hemorrhagic areas. Conclusions Dermoscopy might be useful in the preliminary diagnosis of DLE, and its role in the diagnosis of CHLE and LEP needs further elucidation.

show abstract

Trichoscopic findings of discoid lupus erythematosus alopecia: A cross-sectional study

Cited by 13 publications

References 4 publications

Dermoscopy of discoid lupus erythematosus – a systematic review of the literature

Dermoscopy of discoid lupus erythematosus – a systematic review of the literature

The combined role of clinical, reflectance confocal microscopy and dermoscopy applied to chronic discoid cutaneous lupus and subacutus lupus erythematosus: A case series and literature review

Chronic Cutaneous Lupus Erythematosus in a White Population: Dermoscopic Characteristics by Clinical Subtype, Lesion Location and Disease Duration

Contact Info

Product

Resources

About