Trichoid Basal Cell Carcinoma Found in a Dilated Pore on the Nose

Carlson-Sweet, Kim; Weigand, Dennis A.; MacFarlane, Deborah F.

doi:10.1046/j.1524-4725.2000.00083.x

Cited by 15 publications

(10 citation statements)

References 8 publications

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“…A few basaloid aggregations, including all of the squamous eddy‐like aggregations adjacent to the cornifying areas, were also positive for CKs 1 and 10, suggesting a close relationship between the infundibular component and basaloid aggregations in this BCC. This case is somewhat similar to the architecture recently reported for cases of BCCs with a central large pore (27, 28), although the clinical feature of this case was a nodular lesion with a central, keratotic plug. Interestingly, in two cases (Cases 2, 3), the inner parts of most of the basaloid aggregations that were without cornifying areas were also positive for CKs 1 and 10, suggesting differentiation toward the infundibulum as a whole lesion in these cases.…”

Section: Discussionsupporting

confidence: 88%

Cornification (Keratinization) in Basal Cell Carcinoma: A Histopathological and Immunohistochemical Study of 16 Cases

Misago

Satoh

Narisawa

2004

The Journal of Dermatology

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The concept of keratotic BCC is obscure and not well-defined. To elucidate the histopathological and immunohistochemical properties of cornification in BCC and to clarify the concept of keratotic BCC, by careful examination of 600 BCC specimens, we selected 16 cases of BCC that showed cornification. We investigated the precise histopathological features of these 16 cases, and studied the immunohistochemical expression patterns of anticytokeratin (CK) antibodies (CKs 1, 10, 13, 14, 17) and other antibodies in these cornifying (keratotic) BCCs. We compared these data to those from normal adult hair follicles and three types of cornifying cysts (epidermal cyst, tricholemmal cyst and steatocystoma). Six types of cornification were observed in these BCCs; 1) infundibular type (4 cases) with thin laminated corneocytes expressing CKs 1 and 10, 2) tricholemmal (isthmus) type (9 cases) showing compact, homogenous cornified contents with CK 17 expression on the surrounding cells, 3) inner root sheath type (1 case) characterized by compact, blue-gray corneocytes lined by CK 13 positive-squamous cells with red trichohyalin granules, 4) sebaceous duct type (1 case) characterized by crenulated cornified cells expressing CK 17, 5) apocrine acrosyringium type (2 cases) characterized by small duct-like structures lined by eosinophilic cuticle expressing CEA, in association with keratohyaline granules, and 6) cornifying microcyst type (10 cases) characterized by micro and small cystic structures containing the debris of cornified cells, which was associated with the infundibular or tricholemmal type and could be classified as having the primitive features of the tricholemmal type of cornification. The tricholemmal type could be subdivided into two groups: one with keratohyaline granules and the other without keratohyaline granules, and the cornified contents in approximately 30% of the cornified areas in this type were positive for CK 17. The matrical type of cornification (seventh type) was not seen in our study. The examples described as "keratotic BCC" thus far were similar to BCCs with cornification of the tricholemmal (isthmus) or infundibular type. The cornification in BCCs could be classified into seven types. Excluding the cornifying microcyst type, the tricholemmal type is the most common type of cornification. This type will be abnormal and incomplete in attempts to cornify in the form of an isthmus, occasionally with concomitant exhibition of lower infundibular differentiation. The keratotic BCC is considered to be BCC with cornification of the tricholemmal (isthmus) or infundibular type.

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Section: Discussionsupporting

confidence: 88%

Cornification (Keratinization) in Basal Cell Carcinoma: A Histopathological and Immunohistochemical Study of 16 Cases

Misago

Satoh

Narisawa

2004

The Journal of Dermatology

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“…1,2 No previous reports of trichoblastoma, 3 which is a benign counterpart of BCC, with a dilated pore have been found. We herein report a case of trichoblastoma with a large central pore plugged with keratinaceous debris.…”

Section: Trichoblastoma With a Dilated Porementioning

confidence: 99%

Trichoblastoma with a dilated pore

Misago

Sada

Narisawa

2006

Journal of the American Academy of Dermatology

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“…5 - 7 Each patient had one of the following concomitant diseases: squamous cell carcinoma, trichoblastoma, and trichoid basal cell carcinoma. 8 - 10 Pathologically, a dilated infundibulum filled with keratinous material opens into the surface and extends into the superficial or deep dermis. The lining epithelium is atrophic superficially but proliferative deep in the cavity.…”

Section: Discussionmentioning

confidence: 99%

Multiple vulvar dilated pores in a postmenopausal woman

Shi

Liang

et al. 2017

An. Bras. Dermatol.

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Winer's dilated pore is an infrequent appendageal tumor characterized by a giant comedone on the face, neck, and upper trunk in adults. We report a 57-year-old woman who developed multiple asymptomatic black papules on both labia majora. Histopathology showed grouped dilated follicles lined by keratinizing squamous epithelium in the superficial dermis. The superficial lining epithelium and interfollicular epidermis were atrophic, while the deep epithelium showed mild proliferation and melanin pigmentation with a few short projections extending into the surrounding dermis. We diagnosed multiple Winer's dilated pores based on late-onset lesions and pathological features. This patient may represent the first case of multiple vulvar Winer's dilated pores. We suggest that electrocautery may be effective for treating this type of superficial entity.

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Trichoid Basal Cell Carcinoma Found in a Dilated Pore on the Nose

Cited by 15 publications

References 8 publications

Cornification (Keratinization) in Basal Cell Carcinoma: A Histopathological and Immunohistochemical Study of 16 Cases

Cornification (Keratinization) in Basal Cell Carcinoma: A Histopathological and Immunohistochemical Study of 16 Cases

Trichoblastoma with a dilated pore

Multiple vulvar dilated pores in a postmenopausal woman

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