Trichilemmal Carcinoma on the Thigh: Report of a Case

Abstract

A 79-year-old Japanese man with a trichilemmal carcinoma (TC) on the right thigh is described. To the best of our knowledge, he is the fifth patient with a TC on the thigh reported from Japan.

Multiply Recurrent Trichilemmal Carcinoma With Perineural Invasion and Cytokeratin 17 Positivity

“…Headington 3 first described TLC in 1976, considering TLC to be an entity distinct from the malignant proliferating trichilemmal tumor. To our knowledge, only 51 cases of TLC have been described in the English literature since this initial description 1,2,4–13 …”

Skin cancer in skin of color

“…Such rare malignancies include trichilemmal carcinoma, 201,202 Merkel cell carcinoma, 27,134,203 and microcystic adnexal carcinoma. 91,204,205 The annual age-adjusted incidence of Merkel cell carcinoma from 1986e1994 in blacks was 0.01 per 100,000, compared with 0.23 per 100,000 in whites.…”

Trichilemmal Carcinoma in an African American

“…2 It is important to differentiate trichilemmal carcinoma from other clear cell carcinomas of the skin. [2][3][4][5][6][9][10][11][12][13][14][15][16][17][18][19][20] Only 5 of the 64 cases disclosed the patients' race: 1 Caucasian 18 and 4 Asians (3 Japanese and 1 Chinese). Despite the malignant features, trichilemmal car- cinoma has a relatively benign course and does not recur after excision with clear margins.…”

“…7 In many cases, such distinction may be difficult. 3,[13][14][15] Although the prevalence of trichilemmal carcinoma in skin phototype VI is not known, we believe that the incidence is exceedingly low since trichilemmal carcinoma, regardless of skin phototype, is a rare cutaneous neoplasm. 2,5 To our knowledge the patient presented here is the first reported case in the English language literature of trichilemmal carcinoma in a skin phototype VI individual.…”