Tricalcium phosphate granules or rigid wedge preforms in open wedge high tibial osteotomy: a radiological study with a new evaluation system

Hemert, Wouter L.W. van; Willems, Karel; Anderson, Peter; Heerwaarden, Ronald J van; Wymenga, A. B.

doi:10.1016/j.knee.2004.08.004

Cited by 104 publications

(87 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In all knees remnants of the β-TCP wedge remained visible. Consequently, the maximum score according to the van Hemert classification [15] was phase 3. Nevertheless, within phase 3 substantial differences could be observed in the amount of resorption of the β-TCP wedge over time.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Opening wedge tibial osteotomy for large varus deformity with CeraverTM resorbable beta tricalcium phosphate wedges

Hernigou

Roussignol

Flouzat-Lachaniette

et al. 2009

International Orthopaedics (SICOT)

View full text Add to dashboard Cite

The results in 53 knees that had been treated by proximal tibial opening-wedge osteotomy for large varus deformity and osteoarthritis of the medial compartment were evaluated after a mean length of follow-up of ten years (range, 8-12 years). We used a porous betatricalcium phosphate (β-TCP) wedge because it is resorbable and osteoinductive. All osteotomies were completely consolidated and complete osseointegration of the remnant of the β-TCP wedge took place. However, after a mean maximum follow-up of ten years none of the cases showed complete resorption. After ten years, 40 (81%) of the 53 knees had an excellent or good result, and in 13 knees there was recurrent pain for which six had an arthroplasty. Although the results deteriorated with time, time was not the only determinant of the result. Alignment, measured as the hip-knee-ankle angle on radiographs of the whole limb that were made with the patient bearing weight, was also a determinant of long-term results. The best results were obtained in the knees that had a hip-knee-ankle angle of 183-186 degrees. In these knees, there was no pain and no progression of the arthrosis in either the medial or the lateral tibiofemoral compartment. Of the three knees that had an angle of more than 186 degrees, all five had progressive degenerative changes in the lateral compartment. In the undercorrected knees (an angle of less than 183 degrees), the results were less satisfactory, and there was a tendency toward recurrence of the varus deformity and progression of the arthritis of the medial compartment. However, when the correction was insufficient the deterioration was slow. Therefore, proximal tibial osteotomy is a very suitable operation even for patients who have gonarthrosis of the medial compartment and a large varus deformity. Although, a rigidly standardised and precise operative technique is required as well as accurate radiographic measurements of the mechanical axis of the limb because exact postoperative alignment is the prerequisite for the longest possible period of relief of symptoms after osteotomy, and this exact alignment is difficult to obtain for patients with large varus deformity.

show abstract

Section: Discussionmentioning

confidence: 99%

“…The radiographs were classified in random order according to the radiological classification system described by Van Hemert et al [15]. The classification system by Van Hemert comprises five phases.…”

Section: Preoperative and Postoperative Assessmentsmentioning

confidence: 99%

Opening wedge tibial osteotomy for large varus deformity with CeraverTM resorbable beta tricalcium phosphate wedges

Hernigou

Roussignol

Flouzat-Lachaniette

et al. 2009

International Orthopaedics (SICOT)

View full text Add to dashboard Cite

show abstract

“…To our knowledge, if it is possible to vary the composition of bioceramic materials (composed of Hap and β-TCP) with its inherent porosity, it could be a solution owing to the faster resorption of this BCP together with the sustained release of the antibiotic. In the literature Hap, β-TCP or the combination of both (Hap-TCP) was the most commonly used synthetic augments in high tibial osteotomy (Hoell et al, 2005;Koshino et al, 2003;Gaasbeek et al, 2005;Van Hemert et al, 2004;Gutierres et al, 2007). The use of bone cement as 1751-6161/$ -see front matter Crown Copyright c 2009 Published by Elsevier Ltd. All rights reserved.…”

Section: Introductionmentioning

confidence: 99%

Effect of fluorapatite additive on densification and mechanical properties of tricalcium phosphate

Bouslama

Ayed

Bouaziz

2010

Journal of the Mechanical Behavior of Biomedical Materials

View full text Add to dashboard Cite

“…ChronOS™ and Vitoss Ò are both resorbed over time [25,53]. Resorption of these TCP products is mediated by osteoclastic activity and resorption time varies between 6 and 24 months [21].…”

Section: Biological Propertiesmentioning

confidence: 99%

Bone substitutes in the Netherlands – A systematic literature review

Stok¹,

Lieshout²,

El-Massoudi³

et al. 2011

Acta Biomaterialia

209

130

View full text Add to dashboard Cite

Autologous bone grafting is currently considered as the gold standard to restore bone defects. However, clinical benefit is not guaranteed and there is an associated 8-39% complication rate. This has resulted in the development of alternative (synthetic) bone substitutes. The aim of this systematic literature review was to provide a comprehensive overview of literature data of bone substitutes registered in the Netherlands for use in trauma and orthopedic surgery. Brand names of selected products were used as search terms in three available databases: Embase, PubMed and Cochrane. Manuscripts written in English, German or Dutch that reported on structural, biological or biomechanical properties of the pure product or on its use in trauma and orthopedic surgery were included. The primary search resulted in 475 manuscripts from PubMed, 653 from Embase and 10 from Cochrane. Of these, 218 met the final inclusion criteria. Of each product, structural, biological and biomechanical characteristics as well as their clinical indications in trauma and orthopedic surgery are provided. All included products possess osteoconductive properties but differ in resorption time and biomechanical properties. They have been used for a wide range of clinical applications; however, the overall level of clinical evidence is low. The requirements of an optimal bone substitute are related to the size and location of the defect. Calcium phosphate grafts have been used for most trauma and orthopedic surgery procedures. Calcium sulphates were mainly used to restore bone defects after tumour resection surgery but offer minimal structural support. Bioactive glass remains a potential alternative; however, its use has only been studied to a limited extent.

show abstract

Tricalcium phosphate granules or rigid wedge preforms in open wedge high tibial osteotomy: a radiological study with a new evaluation system

Cited by 104 publications

References 18 publications

Opening wedge tibial osteotomy for large varus deformity with CeraverTM resorbable beta tricalcium phosphate wedges

Opening wedge tibial osteotomy for large varus deformity with CeraverTM resorbable beta tricalcium phosphate wedges

Effect of fluorapatite additive on densification and mechanical properties of tricalcium phosphate

Bone substitutes in the Netherlands – A systematic literature review

Contact Info

Product

Resources

About