Tribo-mechanical properties evaluation of HA/TiO2/CNT nanocomposite

Abstract

In this study, a combination of reverse microemulsion and hydrothermal techniques were used to synthesize HA. A hydrothermal method was used to synthesize HA/TiO2/CNT nanocomposite powders. Cold and hot isostatic pressing techniques were used to fabricate tablet-shaped samples. To investigate the biocompatibility and tribo-mechanical properties of HA/TiO2 and HA/TiO2/CNTs, four samples were prepared with different percentages of CNTs, namely, HA/TiO2 (S0), HA/TiO2/CNT (S1.0), HA/TiO2/CNT (S2.0), and HA/TiO2/CNT (S3.0). The microstructure and morphology of the HA/TiO2/CNTs were characterized by transmission electron microscopy, scanning electron microscopy, energy-dispersive X-ray spectroscopy, and X-ray diffraction. Hardness test results show that S3.0 displayed the highest surface hardness (285 HV) compared to other samples. The wear rate of HA/TiO2/CNT with the highest CNT content showed a decrease compared with those of the other samples. The results from nanoindentation tests showed that Young’s modulus of the S3.0 sample was 58.1% greater than that of the S0 sample. Furthermore, the human MDA-MB-231 cell line demonstrated good binding to the surface of the samples in the in-vitro biocompatibility evaluation of the HA/TiO2/CNT composites.

The Variability in Cytocompatibility and Bone Conduction Based on Different Pore Size and Porosity of n-HA/PA66 Composite Scaffolds

“…The porosity of the biomaterial plays a significant role in the success of an MSC/scaffold construct (Huang et al, 2011). Most studies (Qu et al, 2011;Uddin et al, 2021;Zalnezhad et al, 2021) showed higher porosity was usually associated with greater bone formation, but the reduction in mechanical properties must be considered.…”

“…It is well known that hydroxyapatite (HA) has a composition and structure very close to natural bone minerals and therefore has been considered to be the ideal material to build bone tissue engineering scaffold, and polyamide (PA) has already been proved to possess good biocompatibility and excellent mechanical properties (Hutmacher, 2000;Kang et al, 2000;Chu et al, 2002;Kruyt et al, 2003;Bohner and Baumgart, 2004;Uddin et al, 2021;Zalnezhad et al, 2021;Yuan et al, 2021). Our preceding studies fabricated the nano-hydroxyapatite/ polyamide 66 (n-HA/PA66) composite scaffold, which had both desirable bioactivity and good mechanical properties, and suggested that porous n-HA/PA66 material fulfilled the basic requirements of bone tissue engineering scaffold and had the potential to be applied in orthopedic, reconstructive, and maxillofacial surgery (Marom et al, 2005;Chen et al, 2006;Huang et al, 2007;Wang et al, 2007).…”

Advances in Use of Nanomaterials for Musculoskeletal Regeneration

“…Another way to improve the properties of Ti (Ti-6Al-4V) implants is to cover their surface with GR or CNTs [200]. A HA/TiO 2 /CNT NCP prepared by the hydrothermal method showed good mechanical and physicochemical properties and proved to be suitable for the growth of the human cell line MDA-MB-231 [201].…”

Surface Acoustic Wave (SAW) Sensors for Hip Implant: A Numerical and Computational Feasibility Investigation Using Finite Element Methods

“…Additionally, remote-sensing technology has continued to mature in recent decades with solutions to overcome power constraints. Nowadays, the development of bioinert and biocompatible materials that can be fabricated for artificial implants and bone replacements is becoming increasingly important [10][11][12].…”

“…The delay line area is commonly used as a sensing area to measure physical quantities, such as temperature, humidity and strain [14,15]. SAW sensors with antennas have been shown to effectively transduce pressure information across in vivo studies [10]. In addition to the mentioned applications, SAW sensors have also been used for health monitoring and process monitoring [16].…”