Trianthema portulacastrum linn. (bishkhapra)

Shivhare, Manoj Kumar; Singour, P. K.; Chaurasiya, P K; Pawar, Rajesh Singh

doi:10.4103/0973-7847.99947

Cited by 28 publications

(22 citation statements)

References 15 publications

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“…(family: Aizoaceae) locally known as “Laani” is a fleshy herb with opposite petiolated unequal leaves found in eastern province and southern Hejaz part of Saudi Arabia [ 6 ]. T. portulacastrum is widely used in Arab countries [ 269 ], Africa, India, and southeast Asia, for the treatment of jaundice, liver disorders, stomach problem, arthritis, and inflammation [ 182 , 270 , 271 ]. Laboratory investigations on extracts of the plant have demonstrated significant hepatoprotective, antioxidant, diuretic, analgesic, and anticarcinogenic activity [ 182 ].…”

Section: Resultsmentioning

confidence: 99%

A Review of Hepatoprotective Plants Used in Saudi Traditional Medicine

Alasmari

Al-Elaiwi

Athar

et al. 2014

Evidence-Based Complementary and Alternative Medicine

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Liver disease is one of the major causes of morbidity and mortality across the world. According to WHO estimates, about 500 million people are living with chronic hepatitis infections resulting in the death of over one million people annually. Medicinal plants serve as a vital source of potentially useful new compounds for the development of effective therapy to combat liver problems. Moreover herbal products have the advantage of better affordability and acceptability, better compatibility with the human body, and minimal side effects and is easier to store. In this review attempt has been made to summarize the scientific data published on hepatoprotective plants used in Saudi Arabian traditional medicine. The information includes medicinal uses of the plants, distribution in Saudi Arabia, ethnopharmacological profile, possible mechanism of action, chemical constituents, and toxicity data. Comprehensive scientific studies on safety and efficacy of these plants can revitalise the treatment of liver diseases.

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Section: Resultsmentioning

confidence: 99%

A Review of Hepatoprotective Plants Used in Saudi Traditional Medicine

Alasmari

Al-Elaiwi

Athar

et al. 2014

Evidence-Based Complementary and Alternative Medicine

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show abstract

“…The previous studies on phytochemical constituents of Tp showed that it contains alkaloids, saponins, flavonoids, tannins, phenolic compounds, sterols, proteins and reducing sugars [4]. The preliminary phytochemical investigation revealed the presence of saponins, anthraquinones, flavonoids and alkaloids in the Tp.Cr.…”

Section: Discussionmentioning

confidence: 86%

“…Progression of renal diseases is evident in uncontrolled hypertension and control of blood pressure is an effective strategy in preventing this progression [16]. Tp has also been proven to have antioxidant effect [4] believed to play a key role in controlling cell damage.…”

Section: Discussionmentioning

confidence: 99%

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Diuretic Activity of <i>Trianthema portulacastrum</i> Crude Extract in Albino Rats

Asif¹,

Atif²,

Malik³

et al. 2014

Trop. J. Pharm Res

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Purpose: To evaluate the diuretic effect and acute toxicity of the crude aqueous extract of Trianthema portulacastrum in a rat model. Method: Albino rats were divided into five groups. Control group received normal saline (10 mg/kg), reference group received furosemide (10 mg/kg) and test groups were given different doses of crude extract (10, 30 and 50 mg/kg) by intraperitoneal route. Urine was collected and the total volume of urine excreted was expressed as ml/6 hr/100 g body weight. Diuretic index and Lipschitz values were also calculated to make comparison with normal saline and furosemide treated groups, respectively. Results: Significant diuretic (p < 0.001), kaliuretic (p < 0.001) and natriuretic (p < 0.001) effects were observed in treated groups in a dose-dependent manner. Urinary pH remained mostly unchanged during the course of the study. Diuretic index showed good diuretic activity of the crude extract. Lipschitz values indicated that the crude extract at the dose of 50 mg/kg exhibited 79 % diuretic activity compared with that of the reference, furosemide. No lethal effects were observed among albino mice even at the high dose of 3000 mg/kg. Conclusion: The extract of Trianthema portulacastrum, particularly, at the dose of 50 mg/kg significantly increased the urinary volume and concentration of urinary electrolytes with no signs of toxicity and therefore, is a potential diuretic. Further studies, however, are required to isolate the active constituents.

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“…The plant is bitter, hot, alexiteric, analgesic, stomachic, laxative, and serves as alterative cures for bronchitis, heart disease, blood anaemia, inflammation and piles ascites. 8 The root is applied to the eye to treat corneal ulcers, itching, dimness of sight, and night blindness. 9 The plant has a remarkable protection against the induction of hepatotoxicity.…”

Section: Introductionmentioning

confidence: 99%

Gastroprotective and antisecretory properties of methanolic extract of Trianthema portulacastrum. L in aspirin & pyloric ligature induced gastric ulcer in rats

Prakash¹

2015

PTB Reports

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Objective: The present study was carried out to investigate antiulcer activity of methanolic extract of whole plant of Trianthema portulacastrum L. belonging to the family of Aizoaceae in pylorus ligated and aspirin induced gastric ulcer in rats. Methods: Preliminary methanol extract of Trianthema portulacastrum L. (METP) was subjected to the acute oral toxicity study according to the OECD guideline no. 425. Based on which, two dose levels i.e. 250 and 500 mg/kg were selected for the further study. In both models, we assessed ulcer index, gastric juice volume, gastric pH and total acidity. Ranitidine (50 mg/kg) was used as the positive control. Results: In present study, METP showed significantly decrease in ulcer index in both ulcer models in a dose dependent manner. METP showed a dose dependent significant decrease in gastric juice and total acidity in both the models. A dose dependent increase in gastric pH and total adherent gastric mucus was also produced in METP treated groups. Conclusion: The present study suggested that the antiulcer activity of METP on pylorus ligation induced gastric ulcer can due to anti secretory activity. The mechanism of protection against aspirin induced gastric ulcer can be attributed to 5-lipoxygenase pathway.

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Trianthema portulacastrum linn. (bishkhapra)

Cited by 28 publications

References 15 publications

A Review of Hepatoprotective Plants Used in Saudi Traditional Medicine

A Review of Hepatoprotective Plants Used in Saudi Traditional Medicine

Diuretic Activity of <i>Trianthema portulacastrum</i> Crude Extract in Albino Rats

Gastroprotective and antisecretory properties of methanolic extract of Trianthema portulacastrum. L in aspirin & pyloric ligature induced gastric ulcer in rats

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