Triamcinolone Suspension in Alopecia Areata

Assay of 0.2 % Fluocinolone Acetonide Cream for Alopecia Areata and Totalis

“…The balance responded to neither. It took 3-6 months for regrowth to become visible, in contrast to 3-4 weeks with intralesional corticosteroid therapy [9,10].…”

“…Although superior to other agents previously used for these disorders, the systemic adm inistration of corticosteroids was found to be generally inadvisab le because of the large doses required to stim ulate and m aintain regrowth of hair [4,5]. Intralesional therapy [6][7][8][9][10] by injections of triamcinolone acetonide, has gained wide acceptance as an effective means of inducing regrowth of hair, in alopecia areata particularly. Nevertheless, the response to intralesional deposition of an adrenocorticosteroid is not always uniformly good, and the discomfort of repeated injections is a drawback in children.…”

Development of jet injection and its application to intralesional therapy in dermatology.

“…Successful therapy has been reported in alopecia areata (Orentreich et al, 1960 ;Gombiner and Malkinson, 1961), psoriasis (Gerard, 1960;Readett, 1961;Weidman, 1963), discoid lupus erythematosus (Rowell, 1962;Ferguson Smith, 1962), and in many other conditions, including lichen planus, lichen simplex chronicus, granuloma annulare, sarcoidosis, and pretibial myxoedema (James, 1960(James, , 1961Rebello, 1962).…”

“…The Hypospray (Hingson and Figge, 1952) is probably the most widely studied of such instruments. This employs single-dose Metapules containing up to 1 ml.…”

Topical and Intralesional Administration of Triamcinolone Acetonide: Advantages in Dermatologic Therapy

“…There is no longer any question about the preferential use of corticosteroids, alone or in combination with antibiotics, in the treatment of various skin diseases (1–28). These agents have proven decisive in many clinical states in which the associated inflammation and pruritus are of compelling importance.…”