Trends of the potentially inappropriate medication consumption over 10 years in older adults in the East of France

Bongué, Bienvenu; Naudin, F.; Laroche, Marie‐Laure; Galteau, Marie‐Madeleine; Guy, Claire; Guéguen, R; Convers, Jean-Pierre; Colvez, Alain; Maarouf, Nabil

doi:10.1002/pds.1762

Cited by 50 publications

(58 citation statements)

References 25 publications

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“…This finding was expected, since elderly are most affected by chronic diseases that need pharmacological treatment to control them. Therefore, they usually take more drugs, which could raise the odds of being prescribed PIM [17] and this fact may contribute for the development of NOM, such as ADR.…”

Section: Albert Et Al (2010)mentioning

confidence: 99%

“…________________________________________ However, the Beers list is most often used to evaluate the quality of prescriptions for senior citizens [17] , because it is the best known in the literature [5] . In Brazil, several studies about PIM use in older people have been carried out, however only one evaluated hospital admissions owing to ADR to PIM [15] .…”

Section: Introductionmentioning

confidence: 99%

“…One way to identify the prescription of PIM is the use validated screening tools that incorporate explicit prescribing indicators [17] , such as the Medication Appropriateness Index, the criteria of McLeod and Beers and the Stopp (Screening Tool of Older Persons' potentially inappropriate Prescriptions) methods. ________________________________________ However, the Beers list is most often used to evaluate the quality of prescriptions for senior citizens [17] , because it is the best known in the literature [5] .…”

Section: Introductionmentioning

confidence: 99%

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Safety Assessment of Potentially Inappropriate Medications Use in Older People and the Factors Associated with Hospital Admission

et al. 2011

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-Purpose: Potentially Inappropriate Medications (PIM) use in elderly people may be responsible for the development of Adverse Drug Reaction (ADR) which, when severe, leads to hospital admissions. Objectives: to estimate the prevalence of elderly who had used PIM before being admitted to hospital and to identify the risk factors and the hospitalizations related to ADR arising from PIM. Methods: A descriptive and cross-sectional study was performed in the internal medicine ward of a teaching hospital (Brazil), in 2008. With the aid of a validated form, patients aged ≥ 60 years, with length of hospital stay ≥ 24 hours, were interviewed about drugs taken prior to the hospital admission and the complaints/reasons for hospitalization. Results: 19.1% (59/308) of older patients had taken PIM before hospital admission and in 4.9%; there were a causal relation between the PIM taken and the complaint reported. PIM responsible for admissions were: amiodarone, amitriptyline, cimetidine, clonidine, diazepam, digoxin, estrogen, fluoxetine, lorazepam, short-acting nifedipine and propranolol. 47.0% of the clinical manifestations of PIM-related ADR were: dizziness, fatigue, digoxin toxicity and erythema. Only polypharmacy was detected as a risk factor for the occurrence of ADR of PIM (p = 0.02). Conclusion: PIM use in elderly people is not a risk factor for ADR-related hospital admission. Probably, severe ADR, which lead to hospitalizations of older people, can be explained by idiosyncratic response or the predisposition of these patients to develop adverse drug events, whether or not drugs are classed as PIM.

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Section: Albert Et Al (2010)mentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Safety Assessment of Potentially Inappropriate Medications Use in Older People and the Factors Associated with Hospital Admission

et al. 2011

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“…Concordante con esto, la polifarmacia es un factor de riesgo para el UI ya identificado por otros estudios, siendo catalogado por algunos como el mayor determinante 15,16 .…”

Section: Discussionunclassified

“…También puede ocurrir que el UI Nivel 1 empeore el estado de salud. Un estudio 15 ha reportado la relación que existe entre un peor estado de salud y el riesgo de presentar UI y otro 17 , determinó que los individuos que consumen medicamentos inapropiados empeoran su percepción del estado de salud con el tiempo.…”

Section: Discussionunclassified

Uso inapropiado de medicamentos en adultos mayores: resultados de la Encuesta Nacional de Salud 2010

et al. 2016

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Prevalence of Use of Potentially Inappropriate Medications Among Older Adults Worldwide

Tian,

Chen,

Zeng

et al. 2023

JAMA Netw Open

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ImportanceThe use of potentially inappropriate medications (PIMs) is widespread yet continues to receive little attention in outpatient services.ObjectiveTo estimate the overall prevalence of PIM use in outpatient services.Data SourcesPubMed, Embase, and Web of Science were searched to identify relevant studies published from January 1, 1990, to November 21, 2022.Study SelectionObservational studies that reported the prevalence of PIM use among older patients in outpatient services were screened.Data Extraction and SynthesisTwo reviewers independently selected eligible articles, extracted data, and assessed the risk of bias. A random-effects meta-analysis was conducted to pool the prevalence estimates.Main Outcomes and MeasuresThe global patterns in the prevalence of PIM use among older patients in outpatient services were estimated, and the temporal trends and regional differences in PIM use were investigated.ResultsA total of 94 articles with 132 prevalence estimates were analyzed, including nearly 371.2 million older participants from 17 countries. Overall, the pooled prevalence of PIM use was 36.7% (95% CI, 33.4%-40.0%). Africa had the highest prevalence of PIM use (47.0%; 95% CI, 34.7%-59.4%), followed by South America (46.9%; 95% CI, 35.1%-58.9%), Asia (37.2%; 95% CI, 32.4%-42.2%), Europe (35.0%; 95% CI, 28.5%-41.8%), North America (29.0%; 95% CI, 22.1%-36.3%), and Oceania (23.6%; 95% CI, 18.8%-28.8%). In addition, the prevalence of PIM use is highest in low-income areas. Use of PIMs among older patients has become increasingly prevalent in the past 2 decades.Conclusions and RelevanceThis study of patterns of PIM use by different groups, such as geographic regions and World Bank countries, suggests noticeable geographic environment and economic income differences in the burden of PIMs in outpatient services. Furthermore, the high prevalence trend in the past 2 decades indicates that the global burden of PIM use continues to be worthy of attention.

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Trends of the potentially inappropriate medication consumption over 10 years in older adults in the East of France

Abstract: This study shows a decrease in PIM consumption. Despite an increase of drug use in the elderly, an improving of the quality of this consumption remains possible.

Cited by 50 publications

References 25 publications

Safety Assessment of Potentially Inappropriate Medications Use in Older People and the Factors Associated with Hospital Admission

Safety Assessment of Potentially Inappropriate Medications Use in Older People and the Factors Associated with Hospital Admission

Uso inapropiado de medicamentos en adultos mayores: resultados de la Encuesta Nacional de Salud 2010

Prevalence of Use of Potentially Inappropriate Medications Among Older Adults Worldwide

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