Trends of genitourinary cancer among Saudis

Abomelha, Mohammed S.

doi:10.1016/j.aju.2011.10.006

Cited by 4 publications

(7 citation statements)

References 5 publications

(3 reference statements)

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“…The lowest incidence was found in Pakistan of 1,4/100 000 in 2012. 30 The other studies make mention of the impact on their countries, three of which agree that the rate has been increased in recent years; [31][32][33] The study of Mirzaei et al associates it with a better record of the disease and an increased exposure to risk factors.…”

Section: Africa and Middle Eastmentioning

confidence: 99%

Epidemiology of renal cancer in developing countries: Review of the literature

Medina-Rico

Ramos

Lobo

et al. 2017

CUAJ

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Introduction: Renal cell carcinoma (RCC) is the ninth most common cancer in men, and the 14th most common cancer in women. It has been reported that the incidence of RCC is rising. These changes are more common in developed countries because of better screening programs and disease registry. The aim of this article is to review the epidemiology of RCC around the world. Methods: A literature review on four databases was performed: PubMed, Embase, Lilacs, and Scielo. Studies of incidence, prevalence, mortality, and survival of RCC were taken from different countries. Studies included were published in the last 10 years. Two reviewers independently selected the studies. Results: A total of 5275 references were reviewed by title and abstract. In the end, 42 references were selected for full-text review. The global incidence and prevalence of cancer vary. The highest incidence was described in North America and Northern Europe. In Canada, by 2007 the incidence was 17.9/100 000 and 10.3/100 000 in males and females, respectively. Developing countries like Colombia have fewer incidence rates, finding less information in poor-income areas. Conclusions:We have seen a rise in the incidence and mortality of RCC globally. There is an association between RCC and smoking, obesity, hypertension, and socioeconomic status. Seeing the epidemiological data from some regions in developing countries and the lack of specialists in those places, it can be deduced the existence of an underreporting of

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Section: Africa and Middle Eastmentioning

confidence: 99%

Epidemiology of renal cancer in developing countries: Review of the literature

Medina-Rico

Ramos

Lobo

et al. 2017

CUAJ

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“…However, there are currently no national cancer programs aimed at early detection and prevention. [ 5 ] The increased incidence of small renal masses has led to an expected evolution in the treatment of RCC. Minimally invasive techniques for the treatment of RCC have expanded extensive attractiveness, and now these methods to RCCs have exceeded open techniques in the rate of application.…”

Section: Introductionmentioning

confidence: 99%

Trends in the surgical management of renal cell carcinoma in a contemporary tertiary care setting

Junejo¹,

Alkhateeb²,

Alrumayyan³

et al. 2021

Urol Ann

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Background: In the last three eras, the incidence of renal cell carcinoma (RCC) has increased, due to increased radiological studies. The expected 5-year survival rate has become better, associated with the identification of small size renal masses. However, this survival improvement may be secondary to improved surgical techniques and medical therapies for these malignancies. Objectives: The objective was to report the trends of clinical presentation, peri-operative, oncological outcomes, and surgical management trends for RCCs over the period. Methods: After Institutional Review Board approval, a retrospective study for adult patients was conducted, who presented with renal mass and were managed between 2008 and 2019. Variables, including demographics, perioperative and pathological outcomes analyzed using descriptive statistics for continuous variables reported as mean ± standard deviation and categorical variables values compared by Chi-square test. Survival Analysis calculated using the Kaplan-Meier method. The level of significance is set at P-value < 0.05. Results: A total of 588 patients underwent surgical treatment for kidney cancer from January 2008 to January 2019. 237 (40.30%) were females and 351 (59.69%) males. The clinical presentation was higher as an incidental diagnosis of 58.67%. 71.25% of patients were from outside Riyadh city. Pathology was mostly clear cell RCC 61.22% and grade 2 (57.48%). Tumor size, surgery time, and length of hospital stay showed a significant difference between the three periods (both P > 0.05). Robotic surgery performed more than open ( P < 0.0001). There was no significant difference in the survival time, when compared to patients by the regions and when compared by the primary tumors (Log-Rank P = 0.4821). Patients from the Riyadh region (median = 54.0) had a significantly higher recurrence time (Log-Rank P < 0.0001). Conclusion: There was a rising trend in the incidence of RCC associated with comorbidities and incidental diagnosis. In our study period we found increase in the trend of minimal invasive approach. The size of the tumor, blood loss and operative time decreases over the period of time. The Robotic assisted nephrectomy approach has become increased over the period of time duration in present study.

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“…[ 7 8 9 ] This low incidence rate was attributed to the lower aging population in our country. [ 10 ] However, the incidence of prostate cancer has increased by 48% from 1994 to 2006, which makes it the top raising genitourinary cancer in the country during that period. [ 10 ] Prostate cancer is often found advanced at presentation in Saudi Arabia.…”

Section: Introductionmentioning

confidence: 99%

“…[ 10 ] However, the incidence of prostate cancer has increased by 48% from 1994 to 2006, which makes it the top raising genitourinary cancer in the country during that period. [ 10 ] Prostate cancer is often found advanced at presentation in Saudi Arabia. In the Eastern region, the median prostate-specific antigen (PSA) level at diagnosis was 52 ng/L, 65% had a PSA more than 20 ng/mL, and 52% of their series had bone metastasis at presentation.…”

Section: Introductionmentioning

confidence: 99%

Histopathological diagnoses and patterns in transrectal ultrasound-guided prostatic biopsy series from a large tertiary care center in Saudi Arabia

et al. 2021

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Aim: The aim of the study was to report our transrectal ultrasound (TRUS)-guided prostatic biopsy histopathological diagnoses and clinical findings in our prostate cancer patients in a tertiary care center. Methods: We have reviewed our TRUS biopsy series done in our department from January 2011 to December 2016. We reviewed our patient's prebiopsy prostate-specific antigen (PSA) findings and the histopathological diagnoses and determined the clinical and pathological features of prostate cancer patients in our series. Results: A total of 398 patients underwent 12 core TRUS biopsies. Benign prostatatic hyperplasia was found in 48.5% of the patients and prostate cancer was found in 113 patients (28.4%). Among them, metastatic prostate cancer was found in 51.7% of them. High Gleason score (8–10) was found in 56.6% and a PSA of more than 20 was found in 63.3% of the patients. Conclusion: We recommend a mass public awareness program to encourage our patients to seek early prostate cancer screening and to alert the medical community to encourage more awareness of prostate cancer screening.

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Trends of genitourinary cancer among Saudis

Cited by 4 publications

References 5 publications

Epidemiology of renal cancer in developing countries: Review of the literature

Epidemiology of renal cancer in developing countries: Review of the literature

Trends in the surgical management of renal cell carcinoma in a contemporary tertiary care setting

Histopathological diagnoses and patterns in transrectal ultrasound-guided prostatic biopsy series from a large tertiary care center in Saudi Arabia

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