Epidemiology of renal cancer in developing countries: Review of the literature

Abstract

Introduction: Renal cell carcinoma (RCC) is the ninth most common cancer in men, and the 14th most common cancer in women. It has been reported that the incidence of RCC is rising. These changes are more common in developed countries because of better screening programs and disease registry. The aim of this article is to review the epidemiology of RCC around the world. Methods: A literature review on four databases was performed: PubMed, Embase, Lilacs, and Scielo. Studies of incidence, prevalence, mortality, and survival of RCC were taken from different countries. Studies included were published in the last 10 years. Two reviewers independently selected the studies. Results: A total of 5275 references were reviewed by title and abstract. In the end, 42 references were selected for full-text review. The global incidence and prevalence of cancer vary. The highest incidence was described in North America and Northern Europe. In Canada, by 2007 the incidence was 17.9/100 000 and 10.3/100 000 in males and females, respectively. Developing countries like Colombia have fewer incidence rates, finding less information in poor-income areas. Conclusions:We have seen a rise in the incidence and mortality of RCC globally. There is an association between RCC and smoking, obesity, hypertension, and socioeconomic status. Seeing the epidemiological data from some regions in developing countries and the lack of specialists in those places, it can be deduced the existence of an underreporting of

Molecular pathogenesis of renal cell carcinoma: Impact of the anti‐tumor miR‐29 family on gene regulation

“…Introduction RCC is a common neoplasm, ranking 9th and 14th overall in men and women, respectively. 1 It is also the most common malignant neoplasm in adult kidneys. ccRCC is the most common subtype (approximately 70-80%) of RCC.…”

Prevalence of Kidney, Renal Pelvis, and Ureter Cancers in Isfahan Province, Iran

“…In the current study, there was a 20% increase in incidence from 2011 to 2015. The prevalence rates of renal pelvis and ureter cancers were 0.42 and 0.4, respectively, confirming that transitional cell carcinomas of the ureter and renal pelvis are relatively uncommon (3,(21)(22)(23)(24).…”

“…Accumulating evidence suggests an etiologic role for physical inactivity, alcohol consumption, high parity among women, and occupational exposure to trichloroethylene. Modifications in lifestyle could change many of the mentioned risk factors, suggesting a strong prospect for intervention (3,(21)(22)(23)(24)(25)(26).…”

Microlitiasis testicular como factor de riesgo de Cáncer testicular - Estudio de casos y controles

“…El cáncer testicular es un cáncer poco frecuente entre las patologías tumorales con una incidencia que varía entre países llegando a ser del 2,6/100.000 personas al año en Sur América y de 7,8/100.000 personas al año en Europa. 1 Si bien la confirmación diagnóstica se realiza por el estudio patológico de la pieza quirúrgica, la ecografía es considerada la prueba de elección para identificar tumores testiculares. 2,3 Al igual que su incidencia, la mortalidad del cáncer testicular es baja, con tasas de mortalidad de hasta 0,3/100.000 habitantes.…”

“…2,3 Al igual que su incidencia, la mortalidad del cáncer testicular es baja, con tasas de mortalidad de hasta 0,3/100.000 habitantes. 1 El cáncer testicular es un tumor con buen pronóstico, principalmente por la posibilidad de un tratamiento oportuno cuando llega a realizarse una detección temprana. 4 A pesar de eso, en países como Colombia, se suele retrasar el diagnóstico alrededor de 5 meses por diferentes elementos como lo son las barreras culturales y sociales que disminuyen la consulta de los hombres a los servicios médicos.…”