Trends of and factors associated with cesarean section related surgical site infections in Guinea

Délamou, Alexandre; Camara, Bienvenu Salim; Sidibé, Sidikiba; Camara, Alioune; Dioubaté, Nafissatou; Ayadi, Alison M. El; Tayler-Smith, Katy; Béavogui, Abdoul Habib; Baldé, Mamadou Diouldé; Zachariah, Rony

doi:10.4081/jphia.2019.818

Cited by 5 publications

(5 citation statements)

References 17 publications

(12 reference statements)

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“…This information is important as WHO recommends regular surveillance for SSIs as a way to monitor the results of implementation of IPC procedures. According to Delamou et al (2019), SSI incidence in 10 maternity facilities in Guinea was 5% in 2015 when substantial IPC measures were implemented during the Ebola outbreak [ 17 ]. The SSI incidence in this study at the Bo government hospital maternity unit was higher at 7.5%.…”

Section: Discussionmentioning

confidence: 99%

Incidence of Surgical Site Infection and Use of Antibiotics among Patients Who Underwent Caesarean Section and Herniorrhaphy at a Regional Referral Hospital, Sierra Leone

Carshon-Marsh

Squire²,

Kamara³

et al. 2022

IJERPH

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Surgical site infections (SSIs) are common postoperative complications. Surgical antibiotic prophylaxis (SAP) can prevent the occurrence of SSIs if administered appropriately. We carried out a retrospective cohort study to determine the incidence of SSIs and assess whether SAP were administered according to WHO guidelines for Caesarean section (CS) and herniorrhaphy patients in Bo regional government hospital from November 2019 to October 2020. The analysis included 681 patients (599 CSs and 82 herniorrhaphies). Overall, the SSI rate was 6.7% among all patients, and 7.5% and 1.2% among CS patients and herniorrhaphy patients, respectively. SAP was administered preoperatively in 85% of CS and 70% of herniorrhaphy patients. Postoperative antibiotics were prescribed to 85% of CS and 100% of herniorrhaphy patients. Ampicillin, metronidazole, and amoxicillin were the most commonly used antibiotics. The relatively low rate of SSIs observed in this study is probably due to improved infection prevention and control (IPC) measures following the Ebola outbreak and the current COVID-19 pandemic. A good compliance rate with WHO guidelines for preoperative SAP was observed. However, there was a high use of postoperative antibiotics, which is not in line with WHO guidelines. Recommendations were made to ensure the appropriate administration of SAP and reduce unnecessary use of antibiotics.

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Section: Discussionmentioning

confidence: 99%

Incidence of Surgical Site Infection and Use of Antibiotics among Patients Who Underwent Caesarean Section and Herniorrhaphy at a Regional Referral Hospital, Sierra Leone

Carshon-Marsh

Squire²,

Kamara³

et al. 2022

IJERPH

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“…Among surgical site infections (SSIs), caesarean section is considered an important risk factor for postpartum infections due to uterine skin rupture, bladder catheterization, and contact with health care workers (HCWs) [ 1 , 2 ]. SSI following caesarean section is associated with increased morbidity and mortality, prolonged hospitalization, secondary infertility, and increased health care costs [ 3 ].…”

Section: Introductionmentioning

confidence: 99%

“…During the intrapartum stage, other risk factors are also relevant, including emergency caesarean section, prolonged labor, premature rupture of membranes, and chorioamnionitis [ 7 ]. Moreover, complications generated by post-caesarean SSI include prolonged healing time after surgery due to several factors, e.g., wound dehiscence, prolonged hospital admission, prolonged use of antibiotics, possibility of re-admission and re-suture, sepsis and, in rare cases, mortality [ 1 ].…”

Section: Introductionmentioning

confidence: 99%

Surgical Site Infection Following Caesarean Section by Acinetobacter Species: A Report from a Hyperendemic Setting in the Brazilian Amazon Region

et al. 2021

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Surgical site infection (SSI) following caesarean section is associated with increased morbidity, mortality, and significant health care costs. This study evaluated the epidemiological, clinical, and microbiological features of Acinetobacter spp. in women with SSIs who have undergone caesarean section at a referral hospital in the Brazilian Amazon region. This study included 69 women with post-caesarean SSI by Acinetobacter spp. admitted to the hospital between January 2012 and May 2015. The 69 Acinetobacter isolates were subjected to molecular species identification, antimicrobial susceptibility testing, detection of carbapenemase-encoding genes, and genotyping. The main complications of post-caesarean SSI by Acinetobacter were inadequate and prolonged antibiotic therapy, sepsis, prolonged hospitalization, and re-suture procedures. A. baumannii, A. nosocomialis and A. colistiniresistens species were identified among the isolates. Carbapenem resistance was associated with OXA-23-producing A. baumannii isolates and IMP-1-producing A. nosocomialis isolate. Patients with multidrug-resistant A. baumannii infection showed worse clinical courses. Dissemination of persistent epidemic clones was observed, and the main clonal complexes (CC) for A. baumannii were CC231 and CC236 (Oxford scheme) and CC1 and CC15 (Pasteur scheme). This is the first report of a long-term Acinetobacter spp. outbreak in women who underwent caesarean section at a Brazilian hospital. This study demonstrates the impact of multidrug resistance on the clinical course of post-caesarean infections.

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“…Such infrastructural development has improved IPC compliance. Improved IPC measures and compliance can reduce the incidence of SSIs, as shown by Delamou et al [ 21 ].…”

Section: Discussionmentioning

confidence: 99%

Assessing Changes in Surgical Site Infections and Antibiotic Use among Caesarean Section and Herniorrhaphy Patients at a Regional Hospital in Sierra Leone Following Operational Research in 2021

Kpagoi,

Kamara,

Carshon-Marsh

et al. 2023

TropicalMed

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Surgical site infections (SSIs) are a major public health threat to the success of surgery. This study assessed changes in SSIs and use of antibiotics among caesarean section (CS) and herniorrhaphy patients at a regional hospital in Sierra Leone following operational research. This was a comparative before and after study using routine hospital data. The study included all the CS and herniorrhaphy patients who underwent surgery between two time periods. Of the seven recommendations made in the first study, only one concerning improving the hospital’s records and information system was fully implemented. Three were partially implemented and three were not implemented. The study population in both studies showed similar socio-demographic characteristics. The use of postoperative antibiotics for herniorrhaphy in both studies remained the same, although a significant increase was found for both pre- and postoperative antibiotic use in the CS patients, 589/596 (98.8%) in 2023 and 417/599 (69.6%) in 2021 (p < 0.001). However, a significant decrease was observed in the overall incidence of SSIs, 22/777 (2.8%) in 2023 and 46/681 (6.7%) in 2021 (p < 0.001), and the incidence of SSIs among the CS patients, 15/596 (2.5%) in 2023 and 45/599 (7.5%) in 2021 (p < 0.001). The second study highlights the potential value of timely assessment of the implementation of recommendations following operational research.

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Trends of and factors associated with cesarean section related surgical site infections in Guinea

Cited by 5 publications

References 17 publications

Incidence of Surgical Site Infection and Use of Antibiotics among Patients Who Underwent Caesarean Section and Herniorrhaphy at a Regional Referral Hospital, Sierra Leone

Incidence of Surgical Site Infection and Use of Antibiotics among Patients Who Underwent Caesarean Section and Herniorrhaphy at a Regional Referral Hospital, Sierra Leone

Surgical Site Infection Following Caesarean Section by Acinetobacter Species: A Report from a Hyperendemic Setting in the Brazilian Amazon Region

Assessing Changes in Surgical Site Infections and Antibiotic Use among Caesarean Section and Herniorrhaphy Patients at a Regional Hospital in Sierra Leone Following Operational Research in 2021

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