Trends in the Incidence of Coronary Heart Disease and Stroke and Their Risk Factors in Japan, 1964 to 2003

Kitamura, Akihiko; Sato, Shinichi; Kiyama, Masahiko; Imano, Hironori; Iso, Hiroyasu; Okada, Takeo; Ohira, Tetsuya; Tanigawa, Takeshi; Yamagishi, Kazumasa; Nakamura, Masakazu; Konishi, Masamitsu; Satō, Takashi; Iida, Minoru; Komachi, Yoshio

doi:10.1016/j.jacc.2008.02.075

Cited by 151 publications

(152 citation statements)

References 18 publications

(18 reference statements)

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“…Atherosclerosis is very common in western populations and is reflected in high CHD mortality, while the same holds true for arteriolosclerosis in Japanese and is reflected in high stroke mortality. For example, the ratios of stroke subtypes for Japanese were approximately 20% for large artery occlusive infarction, 20-30% for intraparenchymal hemorrhage and 40% for lacunar infarction, while those for western populations were 40%, 5-10%, and 20% 3) ; however, the recent rise in CHD incidence among urban middle-aged men may indicate a potential increase in atherosclerosis among Japanese subpopulations 9) . Nevertheless, the major ethnic differences in the prevalence of vascular pathology and cardiovascular disease may be in part due to differences in lifestyle, in particular in terms of the diet.…”

Section: Characteristics Of Vascular Pathology In Japanese and Westermentioning

confidence: 98%

“…The age-adjusted incidence of CHD among male . This trend was accompanied by a rise in the prevalence of being overweight (accompanied by increased diastolic blood pressure levels) and hypercholesterolemia and glucose abnormality, mainly due to higher saturated fat intake and a lower level of physical activity 8,9) ; however, the CHD incidence remained low and did not change materially for female residents in rural and urban areas [9][10][11][12][13] and male residents in rural areas 9,[11][12][13] .…”

Section: Characteristics Of Coronary Heartmentioning

confidence: 99%

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Lifestyle and Cardiovascular Disease in Japan

Iso

2011

JAT

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143

108

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The aim was to give on overview of the profile of cardiovascular disease, vascular pathology and the relationships between lifestyle and cardiovascular disease in Japanese. Compared with the United States and Europe, the higher mortality from stroke and lower mortality from coronary heart disease constitute a unique cardiovascular profile for Japan.A selective review of population-based pathology, trend and prospective cohort studies was performed to clarify the characteristics of cardiovascular disease and vascular pathology, trends in the incidence and mortality of cardiovascular disease, and the relationships between lifestyle and cardiovascular disease among Japanese adults. Since the 1970s, mortality from coronary heart disease as well as stroke has declined substantially in Japan, probably due to a major decline in blood pressure levels and for men a more recent decline in smoking, in spite of an increase in body mass index and total cholesterol levels. However, the decline in mortality was smaller and plateaued in middle-aged men aged 30-49 in the metropolitan cities of Tokyo and Osaka. The incidence of coronary heart disease has increased among middle-aged men residing in the suburbs of Osaka. As for the associations between lifestyle and cardiovascular disease, higher sodium, lower calcium and lower animal protein content in the diet and for men higher alcohol consumption may account for the higher prevalence of hypertension and higher risk of stroke for Japanese than for western populations. On the other hand, lower saturated fat (meat) and higher n3 polyunsaturated fat (fish) in the Japanese diet may contribute to the lower prevalence of hypercholesterolemia and lower risk of coronary heart disease among Japanese.Japan is unique among developed countries in that coronary heart disease mortality has been low and has continued to decline, while stroke mortality has declined substantially. However, a recent trend for coronary heart disease incidence to increase among urban men is a cause for concern as a potential source of future problems for public health and clinical practice in Japan.J Atheroscler Thromb, 2011; 18:83-88.

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Section: Characteristics Of Vascular Pathology In Japanese and Westermentioning

confidence: 98%

Section: Characteristics Of Coronary Heartmentioning

confidence: 99%

Lifestyle and Cardiovascular Disease in Japan

Iso

2011

JAT

Self Cite

143

108

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“…Yuhko Suzuki 1) , Taku Sato 2) , Jun Sakuma 2) , Masahiro Ichikawa 2) , Yugo Kishida 2) , Keiko Oda 2) , Yoichi Watanabe 3) , Takeshi Goto 4) , Masahiro Sato 5) , Kenneth E. Nollet 1) , Kiyoshi Saito 2) and Hitoshi Ohto 1)…”

Section: Intracranial Hemorrhage and Platelet Transfusion After Adminunclassified

“…Japan's aging society and growing Westernization of lifestyle, including high calorie and animal fat intake, have contributed to the number of people suffering from arteriosclerotic disease 1,2) . Among the anti -platelet agents (APAs) widely used around the world, acetylsalicylic acid (aspirin) predominates.…”

Section: Introductionmentioning

confidence: 99%

Intracranial hemorrhage and platelet transfusion after administration of anti-platelets agents: Fukushima Prefecture

Suzuki

Sato

Sakuma

et al. 2016

FJMS

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We conducted a case series study to assess intracerebral hemorrhage (ICH) in the context of antiplatelets agents (APAs) and platelet (PLT) transfusion in Fukushima Prefecture. This study included patients who were newly diagnosed with ICH between January 2008 and June 2014 in the neurosurgical hospitals of Fukushima Prefecture. Four of ten neurosurgical hospitals responded to our questionnaire. Of 287 ICH patients, 51 (20.6%) were on APA therapy, of whom PLT transfusion was given to only one persistently bleeding patient who was on dual anti -platelet therapy. In a follow -up survey, 30 out of 51 ICH patients on APA therapy, average age 75 years, were analyzed, of whom 21 (70%) were male. The predominant underlying disease was diabetes mellitus. It is interesting to note that peripheral artery disease and aortic aneurysm were among the indications for APAs. ICH was mainly observed supratentorially. Hematoma enlargement was observed in 13 (44.8%) cases. By day 7, 3 patients (10%) had died from complications of ICH. In this study, we show that ICH during APA therapy matched what was observed in Kanagawa Prefecture. Whether or not a national survey differs, we anticipate greater statistical validity and an opportunity to improve patient outcomes in Japan and around the world.

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“…Due to the super-aged society in Japan, which is rare in the world, the mortality rate due to cardiovascular events is expected to increase further 2,3) ; therefore, the establishment of effective methods for the prevention and treatment of these events is a nationally important problem for devising medical policies 4) . The Ministry of Health, Labour and Welfare established the metabolic syndrome (MetS)-focused health checkup program for the insured aged 40-74 years in April 2008 5,6) .…”

Section: Introductionmentioning

confidence: 99%

Ten-year evaluation of homogeneous low-density lipoprotein cholesterol methods developed by Japanese manufacturers

Nakamura

Koyama

Iso

et al. 2010

JAT

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Aim:The risk index for atherosclerotic cardiovascular diseases in the Japanese metabolic syndromefocused health checkup program was changed from total cholesterol (TC) to low-density lipoprotein cholesterol (LDL-C). We discuss the validity of this change with respect to standardization. Conclusions:The standardization achievement rate of homogeneous LDL-C methods was much lower than that of TC. TC should still be used as a risk index for atherosclerotic cardiovascular diseases. The standardization achievement rate of homogeneous LDL-C should be maintained at 100%, at least using samples with normal lipoprotein profiles. The accuracy and specificity of LDL-C should be further improved before practical and clinical use.

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Trends in the Incidence of Coronary Heart Disease and Stroke and Their Risk Factors in Japan, 1964 to 2003

Abstract: p Ͻ 0.001, †p Ͻ 0.05, ‡p Ͻ 0.01 (level compared with the immediately preceding period). 76Kitamura et al.

Cited by 151 publications

References 18 publications

Lifestyle and Cardiovascular Disease in Japan

Lifestyle and Cardiovascular Disease in Japan

Intracranial hemorrhage and platelet transfusion after administration of anti-platelets agents: Fukushima Prefecture

Ten-year evaluation of homogeneous low-density lipoprotein cholesterol methods developed by Japanese manufacturers

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