Trends in Gastrointestinal cancer incidence in Iran, 2001-2010, with joinpoint analysis

Darabi, Mehdi; Lari, Mohsen Asadi; Motevalian, Seyed Abbas; Motlagh, Ali; Arsang‐Jang, Shahram; Jaberi, Maryam Karimi

doi:10.4178/epih.e2016056

Cited by 27 publications

(25 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The first group, which is also the main group, includes studies using the number of deaths, prevalence, incidence rate, and mortality rate as indicators. These studies were designed to evaluate the epidemiology of esophageal cancer and examine the incidence, prevalence, and mortality due to cancers ( 13 - 16 ). The second group included studies concerning disability adjusted life years (DALYs), years of life lost (YLLs), and years lost due to disability (YLD) as health gap indicators.…”

Section: Introductionmentioning

confidence: 99%

Burden of esophageal cancer in Iran during 1995-2015: Review of findings from the Global Burden of Disease studies

Rahmani

Asiabar

Niakan

et al. 2018

Med. J. Islam. Republic Iran

View full text Add to dashboard Cite

Background: Iran is located in Asian esophageal cancer belt, with age-standardized incidence rate (ASR) of approximately 7 per 100,000 for both men and women. To provide potential solution recommendations for achieving accurate estimations regarding the burden of the disease in Iran, we designed a study to assess the burden of esophageal cancer in Iran during 1995-2015 by collecting data from the Global Burden of Disease studies. Methods: Data were extracted from the Global Burden of Disease (GBD) during 1995-2015, which were published by the Institute for Health Metrics and Evaluation. For this purpose, disability adjusted life years (DALYs), incidence, and prevalence rate were applied to report burden of esophageal cancer based on gender and age group in Iran during 1995-2015. The Cochran-Armitage and t test were used to assess statistical significance. Stata Version 13 and Excel 2016 were used for data analysis. Results: During 1995-2015, in total, 304 102 DALYs (179 562 for males vs. 124 540 for females) were attributed to esophageal cancer in Iran. In both genders and all ages, the number of DALYs increased significantly from 45 018 in 1995 to 74 399 in 2015. Conclusion: Esophageal cancer is still a public health issue in Iran. Most of DALYs were due to years of life lost (YLL), suggesting the need for prevention, early detection, and screening programs. P-value was statistically significant just between male and female groups (p<0.05).

show abstract

Section: Introductionmentioning

confidence: 99%

Burden of esophageal cancer in Iran during 1995-2015: Review of findings from the Global Burden of Disease studies

Rahmani

Asiabar

Niakan

et al. 2018

Med. J. Islam. Republic Iran

View full text Add to dashboard Cite

show abstract

“…Although the incidence of GC has decreased in recent years, approximately 990,000 people are diagnosed with GC each year worldwide and about 738,000 of them die due to GC (Karimi et al, 2014). According to the reports from the Iranian Ministry of Health and recent related studies, GI cancers such as EC and GC are the most common cancers in the East-Azarbaijan province (Naghavi, 2001;Somi et al, 2014;Darabi et al, 2016) but few studies have been conducted on the occurrence of GI cancers, their survival rates, and their related risk factors. Also, since the incidence of GI cancers in East-Azarbayjan Province is significantly high (Somi et al, 2014), identifying the potential risk factor of these fatal diseases with appropriate tools is necessary.…”

Section: Determining Risk Factors For Gastric and Esophageal Cancers mentioning

confidence: 99%

Determining Risk Factors for Gastric and Esophageal Cancers between 2009-2015 in East-Azarbayjan, Iran Using Parametric Survival Models

Zarean

Amini

Yaseri

et al. 2019

Asian Pac J Cancer Prev

View full text Add to dashboard Cite

Background:Esophageal cancer (EC) and Gastric cancer (GC) have been identified as two of the most common cancers in the northeastern regions of Iran. The increasing rates of these types of cancers requires attention. This study aims to assess the potential risk factors for these two cancers and then determine shared risk factors between them in a population of Iranian patients using parametric survival models. Methods:This retrospective cohort study was conducted using 127 patients with EC and 184 patients with GC in East Azarbaijan, Iran who were diagnosed and registered during the years 2009-2010 in Iran’s National Cancer Control Registration Program and were followed for five years. Parametric survival models were used to find the risk factors of the patients. Akaike Information Criteria was used to identify the best parametric model in this study. Interaction analysis was used to determine shared risk factors between EC and GC.Results:The mean (±standard deviation) age of diagnoses for EC and GC were 66.92(±11.95) and 66.5(±11.5) respectively. The survival time ranges of GC patients was (0.07-70.33) and the survival time ranges were from 0.10 to 69.03 months for EC patients. Multivariable Log- logistic model showed that being married (OR=2.25, 95% CI: 1.33 - 3.81) for EC patients and Esophagectomy surgery for EC (OR: 1.62, 95% CI: 1.04 – 2.55) and GC (OR: 1.60, 95% CI: 1.02 – 2.53) had significant effects on survival. Age at the time of diagnosis, job status, and Esophagectomy surgery were statistically comparable regarding their magnitude of effect on survival of two cancers (all Ps>0.05). Conclusion:Esophagectomy surgery and being married were important risk factors in EC and GC. The log-logistic model was the most appropriate statistical approach to identify significant risk factors on survival of both cancers.

show abstract

“…After the results of many studies on the prevalence and incidence of gastrointestinal cancers in Iran were released, IraPEN was developed in 2015, (7,(22)(23)(24)(25). One of the objectives of this program was to prevent colorectal cancer as this cancer is completely preventable (26).…”

Section: Agenda Settingmentioning

confidence: 99%

“…Changes in individuals' lifestyle, socioeconomic conditions, and increasing life expectancy seem to be associated with the current trend of these cancers (7). A recent study indicated that alcohol consumption and tobacco use are important risk factors of esophagus and gastric cancers (8).…”

Section: Introductionmentioning

confidence: 99%

Policies and programs for the prevention of gastrointestinal cancers in Iran: a document analysis

Kabiri

Khodayari‐Zarnaq

Khoshbaten

et al. 2019

Preprint

View full text Add to dashboard Cite

Background Considering the importance of gastrointestinal cancers and their high prevalence in Iran, the analysis of national and local programs and policies are of high importance. The current document review was conducted to assess policies and programs related to the prevention of colon, stomach, liver, esophageal and pancreas cancers in Iran. Methods This paper used 'policy triangle' as a framework to analyze documents related to gastrointestinal cancer prevention in Iran. We searched PubMed and SCOPUS, as well as web pages of Ministry of Health and Medical Education (MOHME), all Medical Sciences Universities, and some related research centers. Documents were analyzed using MAXQDA 10 software. Results Three documents, one guideline, 16 national meeting reports, and 11 articles were found containing or describing interventions directed at the prevention of gastrointestinal cancers in Iran. Also, a large amount of news was obtained from the searched web pages. Findings of this paper are organized based on the four aspects of health policy triangle including content, context, process, and actors. Health affairs of MOHME developed a plan, called 'Iran Package of Essential Non-communicable Disease’ (IraPEN), for preventing three common cancers namely colorectal, breast, and cervix in 2015. The contextual factors affecting prevalence and incidence of gastrointestinal cancers in this country included economic, social, and cultural. Regarding high prevalence and incidence of gastrointestinal cancers in Iran, prevention programs have been developed in this country since 2012 and have been implemented in some areas. However, these programs don’t have any evaluation phase within them. The most effective actor in preventing these cancers in Iran is MOHME. Conclusions Considering the interventions conducted to prevent gastrointestinal cancers in the country, the prevalence and incidence of these cancers have not been diminished. This issue needs care of policy makers in health and other sectors to design and implement policies and strategies in order to prevent these cancers at the primary level. Also, non-governmental organizations might be attracted to provide financial support.

show abstract

Trends in Gastrointestinal cancer incidence in Iran, 2001-2010, with joinpoint analysis

Cited by 27 publications

References 31 publications

Burden of esophageal cancer in Iran during 1995-2015: Review of findings from the Global Burden of Disease studies

Burden of esophageal cancer in Iran during 1995-2015: Review of findings from the Global Burden of Disease studies

Determining Risk Factors for Gastric and Esophageal Cancers between 2009-2015 in East-Azarbayjan, Iran Using Parametric Survival Models

Policies and programs for the prevention of gastrointestinal cancers in Iran: a document analysis

Contact Info

Product

Resources

About