Trends in Gastroesophageal Reflux Disease as Measured by the National Ambulatory Medical Care Survey

Abstract

The frequency of ambulatory visits in the United States for gastroesophageal reflux disease increased significantly between 1995 and 2006. The use of PPI therapy is increasing even more substantially. Older age, female gender, and use of calcium channel blockers were associated with a higher frequency of GERD visits. Health-care utilization for this disorder is increasing perhaps due to our ever-increasing epidemic of obesity.

A 13-nation population survey of upper gastrointestinal symptoms: prevalence of symptoms and socioeconomic factors

“…13 Other studies suggest an increase of GERD prevalence in recent years. 14,15 However, studies on the influence of age and gender on GERD and GER symptoms have yielded inconsistent results 13,[16][17][18] and a low socioeconomic status has been reported to be associated with UGI symptoms in some countries.…”

Characteristics of Consecutive Esophageal Motility Diagnoses After a Decade of Change

“…12 The most recent National Ambulatory Medical Care Survey documented that the rate of GERD-related doctor visits has nearly doubled from 1995 to 2006. 13 Although it remains unclear whether GERD is a cause of IEM or vice versa, it is tempting to consider that the 2 increases in prevalence may be related. Diabetes, specifically diabetic autonomic neuropathy, has also been associated with esophageal dysmotility, decreased amplitudes of contraction, and abnormal wave forms.…”

Oral Nitrate Reductase Activity and Erosive Gastro-esophageal Reflux Disease: A Nitrate Hypothesis for GERD Pathogenesis

“…Gastro-esophageal reflux disease (GERD) has emerged as a leading cause for referral to gastroenterologists and primary care physicians in the West [1]. A similar trend has been recorded with a lag in Asia and the Middle East [2,3].…”