Trends in Eyelid Dermatitis

Crouse, Lauren; Ziemer, Caroline; Lugo-Somolinos, Aída

doi:10.1097/der.0000000000000338

Cited by 7 publications

(2 citation statements)

References 5 publications

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“…According to recent studies, the largest number of patients who present with PD have contact dermatitis, followed by AD and irritative dermatitis, and less often psoriasis, seborrheic dermatitis, rosacea, and dermatomyositis. [ 87 , 88 , 89 , 90 , 91 ].…”

Section: Periocular Dermatitismentioning

confidence: 99%

Features of the Skin Microbiota in Common Inflammatory Skin Diseases

Ferček

Lugović-Mihić

Tambić-Andrašević

et al. 2021

Life

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Many relatively common chronic inflammatory skin diseases manifest on the face (seborrheic dermatitis, rosacea, acne, perioral/periorificial dermatitis, periocular dermatitis, etc.), thereby significantly impairing patient appearance and quality of life. Given the yet unexplained pathogenesis and numerous factors involved, these diseases often present therapeutic challenges. The term “microbiome” comprises the totality of microorganisms (microbiota), their genomes, and environmental factors in a particular environment. Changes in human skin microbiota composition and/or functionality are believed to trigger immune dysregulation, and consequently an inflammatory response, thereby playing a potentially significant role in the clinical manifestations and treatment of these diseases. Although cultivation methods have traditionally been used in studies of bacterial microbiome species, a large number of bacterial strains cannot be grown in the laboratory. Since standard culture-dependent methods detect fewer than 1% of all bacterial species, a metagenomic approach could be used to detect bacteria that cannot be cultivated. The skin microbiome exhibits spatial distribution associated with the microenvironment (sebaceous, moist, and dry areas). However, although disturbance of the skin microbiome can lead to a number of pathological conditions and diseases, it is still not clear whether skin diseases result from change in the microbiome or cause such a change. Thus far, the skin microbiome has been studied in atopic dermatitis, seborrheic dermatitis, psoriasis, acne, and rosacea. Studies on the possible association between changes in the microbiome and their association with skin diseases have improved the understanding of disease development, diagnostics, and therapeutics. The identification of the bacterial markers associated with particular inflammatory skin diseases would significantly accelerate the diagnostics and reduce treatment costs. Microbiota research and determination could facilitate the identification of potential causes of skin diseases that cannot be detected by simpler methods, thereby contributing to the design and development of more effective therapies.

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Section: Periocular Dermatitismentioning

confidence: 99%

Features of the Skin Microbiota in Common Inflammatory Skin Diseases

Ferček

Lugović-Mihić

Tambić-Andrašević

et al. 2021

Life

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“…4,9,27 Multiple studies across the past decade have found nickel to be among the most common contact allergens, if not the most common. 9,26,28 A few reports have noted ACD-inducing nickel found in eyelash curlers. 4,29 Therefore, avoidance of eyelash curlers may also be advisable, because of the potential allergenic composition of their metal frames.…”

Section: Nickel and Cobaltmentioning

confidence: 99%

Seven Common Allergen Groups Causing Eyelid Dermatitis: Education and Avoidance Strategies

Huang¹,

Yiannias²,

Killian³

et al. 2021

OPTH

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Objective: Eyelid dermatitis is most commonly attributed to allergic response. This retrospective clinical study identifies common allergens with eyelid involvement and addresses a literary gap by providing a clear approach for effective management of periorbital allergic contact dermatitis (ACD) recurrence. Methods: Charts of 215 patients diagnosed with periorbital dermatitis who were patch tested with Mayo Clinic Standard Series, Extended Standard Series, and personal products from 2013 to 2017 were examined. Positive reaction rates for patients with eyelid involvement were compared to those without. Findings were also compared to North American Contact Dermatitis Group (NACDG) 2013-2014 and Mayo Clinic Contact Dermatitis Group (MCCDG) 2011-2015 general patch test populations. Results: The 215 patients showed more common allergy to shellac, benzalkonium chloride, acrylates, and surfactants than the NACDG and MCCDG study populations. Periorbital ACD allergen groups eliciting the highest positive reaction rates were, in descending order: metals, shellac, preservatives, topical antibiotics, fragrances, acrylates, and surfactants. Of the corticosteroids, only tixocortol pivalate (the screening agent for prednisolone and fluorometholone) and budesonide elicited positive reactions. Conclusion:The top seven eyelid ACD allergen groups were identified. Avoidance of these allergens can be straightforward, with initial empiric counseling and free, online allergen avoidance programs. Patients who are unresponsive to avoidance should undergo patch testing.

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Eczematous Disorders

Mughal,

Ingram

2024

Rook's Textbook of Dermatology

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Eczematous disorders comprise manifestations of inflammatory skin conditions that may be aspects of atopic dermatitis, contact dermatitis or other conditions that in the main have an eczema‐like nature in both their presentation and response to treatment. Eczema and its management is covered in other chapters of this book. However, it is useful to consider the common aspects of nummular eczema, asteatotic eczema, lichenification and erythroderma in more detail together as sometimes the distinction between diagnoses is difficult with considerable overlap. Infectious eczema, whilst sharing physical characteristics with other eczemas, will respond differently to treatments. There are differences in how eczema presents on the hands, lower legs and the eyelids. Finally some other eczematous conditions are covered such as pityriasis alba and post‐traumatic eczema.

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Trends in Eyelid Dermatitis

Cited by 7 publications

References 5 publications

Features of the Skin Microbiota in Common Inflammatory Skin Diseases

Features of the Skin Microbiota in Common Inflammatory Skin Diseases

Seven Common Allergen Groups Causing Eyelid Dermatitis: Education and Avoidance Strategies

Eczematous Disorders

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