Trends in data processing of comprehensive two-dimensional chromatography: State of the art

Multi-Dimensional Separations of Polymers

“…18 The twodimensional chromatograms are reconstructed from the string of one-dimensional chromatograms recorded by the detector. 17,19 A possible valve configuration is shown in Figure 1.…”

Profiling Water-Soluble Organic Matter from Urban Aerosols Using Comprehensive Two-Dimensional Liquid Chromatography

“…As a result, the sample-to-sample comparison is improved, and the sample characterization is facilitated especially when LC£LC is combined with the informing power of a multichannel detector. Nevertheless, extracting useful information from a large amount of multi-dimensional data is still one of the major drawbacks for a wider application of LC£LC-DAD procedures (Matos et al 2012). Therefore, in this work, a mathematical procedure, introduced recently by Matos et al (2013), has been used to deal with a large amount of data generated by the PALC£SEC-DAD system and draw a 3D fingerprinting for each WSOM sample, which alongside other samples can be used to identify different patterns associated with the specific properties of each sample under study.…”

Application of Multiway Calibration in Comprehensive Two-Dimensional Gas Chromatography

“…After this, absolute quantification can be achieved with the help of standard calibration strategies, including the following methods: normalization, internal standard, external standard, and standard addition [21,22]. In order to generate calibration models in GC Â GC data, a two-step approach is accomplished: First, the deconvolution of unresolved chromatographic peaks is performed and then a univariate calibration model is developed.…”

“…Initially, it was used in psychometrics field. However, some requirements must be met by the experimental data for a successful application of PARAFAC: linear detector response with concentration variation and no shifts in the retention time of GC Â GC peaks [22]. Since then, it has been gaining more and more interest in chemometrics due to the analytic instrument improvements and computer development.…”