Trends in childhood leukemia mortality over a 25-year period

Couto, Arnaldo Cézar; Ferreira, Jeniffer Dantas; Koifman, Rosalina Jorge; Monteiro, Gina Torres Rego; Pombo-de-Oliveira, Maria do Socorro; Koifman, Sérgio

doi:10.2223/jped.2027

Cited by 10 publications

(9 citation statements)

References 23 publications

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“…These decreases included a higher mortality rate for boys compared with girls, as confirmed by our data for 2006 to 2008. The leukemia mortality rate in the state of Rio de Janeiro declined during 1980 and 2006 and was also more pronounced in boys (25). …”

Section: Discussionmentioning

confidence: 99%

Childhood cancer mortality trends in Brazil, 1979 – 2008

Ferman¹,

Santos²,

Ferreira³

et al. 2013

Clinics

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OBJECTIVES:Childhood cancer mortality has substantially declined worldwide as a result of significant advances in global cancer care. Because limited information is available in Brazil, we analyzed trends in childhood cancer mortality in five Brazilian regions over 29 years.METHODS:Data from children 0-14 years old were extracted from the Health Mortality Information System for 1979 through 2008. Age-adjusted mortality rates, crude mortality rates, and age-specific mortality rates by geographic region of Brazil and for the entire country were analyzed for all cancers and leukemia. Mortality trends were evaluated for all childhood cancers and leukemia using joinpoint regression.RESULTS:Mortality declined significantly for the entire period (1979-2008) for children with leukemia. Childhood cancer mortality rates declined in the South and Southeast, remained stable in the Middle West, and increased in the North and Northeast. Although the mortality rates did not unilaterally decrease in all regions, the age-adjusted mortality rates were relatively similar among the five Brazilian regions from 2006-2008.CONCLUSIONS:Childhood cancer mortality declined 1.2 to 1.6% per year in the South and Southeast regions.

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Section: Discussionmentioning

confidence: 99%

Childhood cancer mortality trends in Brazil, 1979 – 2008

Ferman¹,

Santos²,

Ferreira³

et al. 2013

Clinics

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“…The data suggest that the observed increases in brain cancer and lymphocytic leukemia may actually represent real increases and not merely the result of improved reporting of mortality data in the country. Importantly, this rise in mortality from lymphocytic leukemia contrasts with the downward trend in mortality rates from leukemia as a whole in individuals under 15 years of age in Brazil 16 .…”

Section: Type Of Cancer (Icd-10)mentioning

confidence: 81%

Cancer incidence, hospital morbidity, and mortality in young adults in Brazil

Santos¹,

Melo²,

Koifman³

et al. 2013

Cad. Saúde Pública

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There are still relatively few studies in the world on cancer incidence and mortality in young adults. The current study aimed to explore cancer distribution in young adults in Brazil. A descriptive study was conducted on cancer incidence (selected State capitals), hospital morbidity, and mortality (Brazil and selected capitals) in the 20-24-year age strata in 2000-2002, and trends in cancer mortality rates in Brazil in 1980-2008 in the same population. Testicular cancer was the principal anatomical site in young adult males; in young adult women, the main sites were thyroid, uterine cervix, and Hodgkin disease. Brain cancer was the principal cause of death from cancer in both sexes, and time trends in mortality showed an increase in mortality from brain cancer in men and from lymphocytic leukemia in both sexes. As a whole, the results show an epidemiological pattern of cancer in young adults with regional distribution characteristics.

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“…In developed countries, infant mortality caused by leukemia decreased significantly in the last 30 years, although the incidence remained unchanged. In contrast, in developing countries, the incidence rate is maintained, but the infant mortality rates because of leukemia remain high [9,24,25].…”

Section: Resultsmentioning

confidence: 99%

Distribution and survival of leukemias in the mesoregion of the Potiguar West

2018

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In the mesoregion of the Potiguar West, Rio Grande do Norte, Brazil, literature concerning distribution and survival rates of leukemia in the population is sparse. This study intends to perform this analysis, exploring epidemiological data on patients, up to 100 years old, diagnosed between 2005 and 2014. In total, 183 patients with any type of leukemia were considered; acute myeloid leukemia was the most frequent (66 cases). Male patients were predominant (59%) and most cases did not progress to death (59.1%). In relation to survival, patients with acute myeloid leukemia presented less survival of 10 years after diagnosis, while patients with chronic lymphoid leukemia were most survival rates. Thus, it was possible to better characterize leukemia in this region, which is critical to identify possible risk factors and establish priorities on prevention, planning, management and evaluation of health services.

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Trends in childhood leukemia mortality over a 25-year period

Cited by 10 publications

References 23 publications

Childhood cancer mortality trends in Brazil, 1979 – 2008

Childhood cancer mortality trends in Brazil, 1979 – 2008

Cancer incidence, hospital morbidity, and mortality in young adults in Brazil

Distribution and survival of leukemias in the mesoregion of the Potiguar West

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