“…These specific patient factors may mediate responses to recanalization therapies in general, EVT in particular (Bang et al, 2011;Elijovich et al, 2016;Gerber et al, 2016;. Therefore, multimodal strategies, including-but not limited to-systems-based approaches to reduce treatment delay in acute ischaemic stroke (Bhaskar, Thomas, et al, 2019;Venkat et al, 2018), advanced histopathological analyses to delineate underlying aetiology in cryptogenic stroke (Bhaskar, Cordato, et al, 2017;Bhaskar, Saab, et al, 2019) and advanced imaging to estimate tissue at risk and collateral status (Bang et al, 2011;, could improve acute stroke workflow (Bhaskar et al, 2020), diagnosis and treatment planning (Bhaskar et al, 2018).…”