Trends and predictions for gastric cancer mortality in Brazil

Abstract

Regional differences were demonstrated in the mortality rates for gastric cancer in Brazil, and the least developed regions of the country will present increases in projected mortality rates.

Unequal burden of mortality from gastric cancer in Brazil and its regions, 2000–2015

“…In 2015, there were an estimated 1.3 (1.2-1.4) million new cases worldwide of GC, 819,000 (795,000-844,000) deaths, and 17.4 (16.9-18) million disability-adjusted life years (DALYs) with 98.0% caused by years of life lost (YLLs) and 2% by years lived with disability (YLDs) [1]. Interestingly, while most countries have reported an increase of 5-year survival rates, in Brazil decreasing rates were observed [6,9,11,12]. A previous study from Brazil has shown that the rates decreased in the Central-West, Southeast, and South regions, remained relatively stable in the North, and increased in the Northeast from 1980 to 2009 [11].…”

“…In Brazil, GC is the fourth most common cancer among men and the fifth most common among women [8]. In more than 75% of cases, GC is diagnosed in advanced stages [8,9]. Five-year survival rates in Brazil declined in the past decades, in contrast to the upward trend seen in most other countries [1,2,6,9].…”

“…Low socioeconomic status has been associated with higher risk of GC incidence, regardless of sex or country of origin [10]. There are few studies on GC-related mortality showing different epidemiological patterns among the different Brazilian geographic regions [9,11,12]. Overall, male sex, increased age and lower socio-economic status are associated with higher mortality [9,10].…”

“…There are few studies on GC-related mortality showing different epidemiological patterns among the different Brazilian geographic regions [9,11,12]. Overall, male sex, increased age and lower socio-economic status are associated with higher mortality [9,10]. The mortality rates in the north and northeast, Brazil's less developed regions, are expected to increase [9,11].…”

“…Overall, male sex, increased age and lower socio-economic status are associated with higher mortality [9,10]. The mortality rates in the north and northeast, Brazil's less developed regions, are expected to increase [9,11]. However, these studies considered only underlying causes of death, and there are no systematic nationwide studies evaluating the spatiotemporal patterns of GC mortality rates.…”