Trends and Advances in Electrochemiluminescence Nanobiosensors

Abstract

The rapid and increasing use of the nanomaterials (NMs), nanostructured materials (NSMs), metal nanoclusters (MNCs) or nanocomposites (NCs) in the development of electrochemiluminescence (ECL) nanobiosensors is a significant area of study for its massive potential in the practical application of nanobiosensor fabrication. Recently, NMs or NSMs (such as AuNPs, AgNPs, Fe3O4, CdS QDs, OMCs, graphene, CNTs and fullerenes) or MNCs (such as Au, Ag, and Pt) or NCs of both metallic and non-metallic origin are being employed for various purposes in the construction of biosensors. In this review, we have selected recently published articles (from 2014–2017) on the current development and prospects of label-free or direct ECL nanobiosensors that incorporate NCs, NMs, NSMs or MNCs.

A hybrid nanocomposite of CeO2–ZnO–chitosan as an enhanced sensing platform for highly sensitive voltammetric determination of paracetamol and its degradation product p-aminophenol

“…[19][20][21][22][23][24][25] Notably, the appearance of various advanced electrode modied nanomaterials signicantly enhanced the sensing performance. [26][27][28][29][30][31] Due to their attractive potential, nanostructured materials such as nanocomposites have been incorporated into electrochemical sensors for biological and pharmaceutical analyses. [29][30][31][32][33][34][35] Nanocomposites of a variety of sizes, shapes, and compositions are changing nowadays bioanalytical measurement.…”

“…[26][27][28][29][30][31] Due to their attractive potential, nanostructured materials such as nanocomposites have been incorporated into electrochemical sensors for biological and pharmaceutical analyses. [29][30][31][32][33][34][35] Nanocomposites of a variety of sizes, shapes, and compositions are changing nowadays bioanalytical measurement. Chitosan along with metal oxide nanoparticles has much interest for the fabrication of electrochemical sensor.…”

A Label-free Cardiac Troponin T Electrochemiluminescence Immunosensor Enhanced by Graphene Nanoplatelets

“…The utilization of nanomaterials in biosensors, particularly those derived from carbon, contributes to multitudinous benefits such as enlargement of working surface area for bioconjugation process and improvement in the electroconductivity of the particular biosensors. 7 Carbon nanomaterials (CNMs) are known to possess remarkable structural and electrochemical attributes, making them a fascinating nanomaterial to be exploited for the fabrication of a biosensor. 7 Graphene, singlewalled carbon nanotubes (SWCNTs) and other carbon allotropes have been elucidated to have improved the sensitivity of the overall biosensor.…”

“…7 Carbon nanomaterials (CNMs) are known to possess remarkable structural and electrochemical attributes, making them a fascinating nanomaterial to be exploited for the fabrication of a biosensor. 7 Graphene, singlewalled carbon nanotubes (SWCNTs) and other carbon allotropes have been elucidated to have improved the sensitivity of the overall biosensor. [8][9][10][11] Graphene, being a 2-dimentional nanomaterial, is made up of sp 2 hybridized carbon possessing 2019 © The Japan Society for Analytical Chemistry † To whom correspondence should be addressed.…”

A Sensitive Electrochemiluminescence Sensor for Brilliant Blue FCF Using Ru(bpy)32+ Immobilized Zn-MOF

“…Electrochemiluminescence (ECL) sensors have been developed and widely used in food additives analysis, 15 biological research, 16 environmental monitoring 17 and clinical test. 18 Compared to conventional methods, ECL has a lower background, wider dynamic range and higher sensitivity, since it integrates the distinct advantages of electrochemistry and spectroscopy. 19,20 The tris(bipyridine)ruthenium(II) (Ru(bpy)3 2+ ) is the most-common used luminophore in ECL system due to its stably chemical structure, wide pH range, excellent luminescence and solubility in aqueous medium.…”