Trend in Hip Fracture Incidence and Mortality in Korea: A Prospective Cohort Study from 2002 to 2011

Ha, Yong‐Chan; Park, Yong Bum; Nam, Kwang Woo; Kim, Sang-Rim

doi:10.3346/jkms.2015.30.4.483

Cited by 64 publications

(47 citation statements)

References 28 publications

(62 reference statements)

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“…[829] The mean time to mobilization was also found to be reduced in the treatment group. In 2 studies with pertrochanteric fractures,[3033] teriparatide was associated with less pain and a shorter time to functional recovery.…”

Section: Resultsmentioning

confidence: 99%

Current Role and Application of Teriparatide in Fracture Healing of Osteoporotic Patients: A Systematic Review

et al. 2017

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BackgroundThe use of osteoanabolic agents to facilitate fracture healing has been of heightened interest to the field of orthopaedic trauma. This study aimed to evaluate the evidence of teriparatide for fracture healing and functional recovery in osteoporotic patients.MethodsWe performed a literature search in PubMed, EMBASE, Web of Science, and the Cochrane Library using terms including “Fracture” [tiab] AND “Teriparatide [tiab] OR “PTH” [tiab].ResultsThis systematic review included 6 randomized clinical trials, 4 well-controlled retrospective studies, and 1 retrospective post hoc subgroup analysis. Fracture location was 2 in pelvis, 3 in proximal femur, 1 in distal femur, 1 in shoulder, 2 in wrist and 2 in spine. The use of teriparatide yielded positive effects on radiographic bone healing in 6 studies, but was not associated with better radiographic outcome in 3. In terms of functional recovery, teriparatide injection was related with decrease in pain or shorter time to mobilization in 6 studies, but not related with pain numerical scale and mobility in 3.ConclusionsOur findings suggest that teriparatide provide selective advantages to fracture healing or functional recovery in the management of osteoporotic fractures. A better understanding of the role of teriparatide on osteoporotic fractures requires greater evidences from large volume prospective trials.

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Section: Resultsmentioning

confidence: 99%

Current Role and Application of Teriparatide in Fracture Healing of Osteoporotic Patients: A Systematic Review

et al. 2017

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“…Hip fractures can introduce various serious physical complications following prolonged immobility. Thus, the reported mortality rates of patients with hip fractures at 1 month and 6 months are 2.7% and 10.8%, respectively [2]. Several risk factors related to postoperative mortality after hip surgeries have been reported in the previous reports, and malnutrition is noted to be an important risk factor among them [3,4].…”

Section: Introductionmentioning

confidence: 96%

Geriatric Nutritional Risk Index and Controlling Nutritional Status Score can predict postoperative 180-day mortality in hip fracture surgeries

Kotera

2019

JA Clin Rep

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Background: The Geriatric Nutritional Risk Index (GNRI) based on serum albumin level and body weight and the Controlling Nutritional Status Score (CONUT) based on serum albumin level, total cholesterol level, and total lymphocyte count were created to evaluate objectively a patient's nutritional status in 2005. Here we validated the usefulness of the GNRI and the CONUT as a prognostic factor of the 180-day mortality in patients who underwent hip fracture surgeries. We retrospectively collected data from patients with hip surgeries performed from January 2012 to December 2018. The variables required for the GNRI and the CONUT and the factors presumably associated with postoperative mortality including the patients' characteristics were collected from the medical charts. Intergroup differences were assessed with the χ 2 test with Yates' correlation for continuity in category variables. The Mann-Whitney U test was used to test for differences in continuous variables. We validated the power of the GNRI and the CONUT values to distinguish patients who died ≤ 180 days post-surgery from those who did not, by calculating the area under the receiver operating characteristic curve (AUC). The correlation between these two models was analyzed by Spearman's rank correlation (ρ). Results: We retrospectively examined the cases of 607 patients aged 87 ± 6 (range 70-102) years old. The 180-day mortality rate was 5.4% (n = 33 non-survivors). The GNRI value in the non-survivors was 83 ± 9 (range 66-111), which was significantly lower than that in the survivors at 92 ± 9 (range 64-120). The CONUT value in the nonsurvivors was 6 ± 3 (range 1-11), which was significantly higher than that in the survivors at 4 ± 2 (range 0-11). The AUC value to predict the 180-day mortality was 0.74 for the GNRI and 0.72 for the CONUT. The ρ value between these two models was 0.61 in the total of 607 patients and was 0.78 in the 33 non-survivors. Conclusions: Our results suggest that the GNRI and the CONUT are a simple and useful tool to predict the 180day mortality in patients who have undergone a hip surgery.

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“…Femoral neck fractures can introduce various serious physical complications such as pneumonia subsequent to prolonged immobility. Thus, femoral neck fractures can be an important cause of postoperative mortality, and the reported mortality rates of patients with femoral neck fractures at 1 month, 6 months, and 1 year are 2.7, 10.8, and 16.3%, respectively [2]. A better understanding of postoperative complications in patients with femoral neck surgeries is therefore needed.…”

Section: Introductionmentioning

confidence: 99%

The Surgical Apgar Score can help predict postoperative complications in femoral neck fracture patients: a 6-year retrospective cohort study

Kotera

2018

JA Clin Rep

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Introduction: The postoperative mortality rate following a femoral neck fracture remains high. The Surgical Apgar Score (SAS), based on intraoperative blood loss, the lowest mean arterial pressure, and the lowest heart rate, was created to predict 30-day postoperative major complications. Here, we evaluated the relationship between the SAS and postoperative complications in patients who underwent femoral neck surgeries. Methods: We retrospectively collected data from patients with femoral neck surgeries performed in 2012-2017 at Kumamoto Central Hospital. The variables required for the SAS and the factors presumably associated with postoperative complications including the patients' characteristics were collected from the medical charts. Intergroup differences were assessed with the χ 2 test with Yates' correlation for continuity in category variables. The Mann-Whitney U test was used to test for differences in continuous variables. We assessed the power of the SAS value to distinguish patients who died ≤ 90 days post-surgery from those who did not, by calculating the area under the receiver operating characteristic curve (AUC). Results: We retrospectively examined the cases of 506 patients (94 men, 412 women) aged 87 ± 6 (range 70-102) years old. The 90-day mortality rate was 3.4% (n = 17 non-survivors). There were significant differences between the non-survivors and survivors in body mass index (BMI), the presence of moderate to severe valvular heart disease, albumin concentration, the American Society of Anesthesiologists (ASA) classification, and the SAS. The 90-day mortality rate in the SAS ≤ 6 group (n = 97) was 10.3%, which was significantly higher than that in the SAS ≥ 7 group (n = 409), 1.7%. The AUC value to predict the 90-day mortality was 0.70 for ASA ≥ 3 only, 0.71 for SAS ≤ 6 only, 0.81 for SAS ≤ 6 combined with ASA ≥ 3, and 0.85 for SAS ≤ 6 combined with albumin concentration < 3.5 g/ dl, BMI ≤ 20, and the presence of moderate to severe valvular heart disease. Conclusions: Our results suggest that the SAS is useful to evaluate postoperative complications in patients who have undergone a femoral neck surgery. The ability to predict postoperative complications will be improved when the SAS is used in combination with the patient's preoperative physical status.

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Trend in Hip Fracture Incidence and Mortality in Korea: A Prospective Cohort Study from 2002 to 2011

Cited by 64 publications

References 28 publications

Current Role and Application of Teriparatide in Fracture Healing of Osteoporotic Patients: A Systematic Review

Current Role and Application of Teriparatide in Fracture Healing of Osteoporotic Patients: A Systematic Review

Geriatric Nutritional Risk Index and Controlling Nutritional Status Score can predict postoperative 180-day mortality in hip fracture surgeries

The Surgical Apgar Score can help predict postoperative complications in femoral neck fracture patients: a 6-year retrospective cohort study

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