“…Even though the application of standard methods to compositional data yielded interpretable and apparently reasonable results, the application of standard methods in compositional data are, at best, inappropriate [26]. As explained by Aitchison [25], Pawlowsky-Glahn and Egozcue [26], Filzmoser, Hron, and Reimann [60], Marcillo-Delgado, Ortego and Pérez-Foguet [80], Cruz-Sandoval, Ortego and Roca [29], the use of standard statistical methods in compositional data originate problems, such as prediction of values outside the sample space, spurious correlations and sub-compositional incoherence, among others.…”