Treatment of Xanthelasma Palpebrarum With Intralesional Pingyangmycin

Abstract

Intralesional pingyangmycin is a cheap, effective, and safe treatment for xanthelasma, which has been well accepted by patients.

Treatment of Grade I and II types of xanthelasma palpebrarum with intralesional heparin sodium

“…The treatment of xanthelasma remains a challenge in clinical practice. Although many methods have been proposed to deal with xanthelasma, including cryotherapy, trichloroacetic acid peeling, electric cauterization, laser therapy (e.g., carbon dioxide, argon, Q‐switched Nd: YAG, Er: YAG, and pulsed dye lasers), surgical resection Nair, ), and intralesional injection of pingyangmycin (Wang et al, ). The physical approaches, such as cryotherapy, trichloroacetic acid peeling, and electric cauterization, only affect the surface or the superficial layer of the skin, and the damage to the skin is quite notable, thereby increasing the chances of leaving scars with hypopigmentation or hyperpigmentation.…”

Effect of a high‐cholesterol diet on lipoprotein metabolism and xanthoma formation in rabbits

“…12 However, none of these treatments have proven effective, and they can cause serious complications, including recurrence, scarring, and pigment alteration (hypo-or hyperpigmentation). 3 In addition, some studies have reported that the invasive depth of xanthelasma histiocytes (foam cells) is generally much deeper than previously thought, reaching the orbicularis oculi. 13 Consequently, complete removal of pathological tissues remains problematic.…”

“…Although xanthelasma causes neither clinical symptoms nor dysfunction, it usually occurs on sites that can seriously affect individual appearance . However, surgical management of xanthelasma remains difficult.…”

“…Many methods to treat xanthelasma have been proposed, including cryotherapy, trichloroacetic acid peeling, electric cauterization, laser therapy (eg, carbon dioxide, argon, Q‐switched Nd:YAG, Er:YAG, and pulsed dye lasers), and surgical resection . However, none of these treatments have proven effective, and they can cause serious complications, including recurrence, scarring, and pigment alteration (hypo‐ or hyperpigmentation) . In addition, some studies have reported that the invasive depth of xanthelasma histiocytes (foam cells) is generally much deeper than previously thought, reaching the orbicularis oculi .…”

“…2 Although xanthelasma causes neither clinical symptoms nor dysfunction, it usually occurs on sites that can seriously affect individual appearance. 3 However, surgical management of xanthelasma remains difficult. Many methods to treat xanthelasma have been proposed, including cryotherapy, 4 trichloroacetic acid peeling, 5 electric cauterization, 6 laser therapy (eg, carbon dioxide, 7 argon, 8 Q-switched Nd:YAG, 9 Er:YAG, 10 and pulsed dye lasers), 11 and surgical resection.…”