2019
DOI: 10.1159/000495909
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Treatment of Tinea Capitis

Abstract: Tinea capitis is a common fungal infection of the hair of the scalp affecting predominately prepubertal children. In the US, griseofulvin has been considered a first-line therapy agent for tinea capitis since the 1960s. However, it has been falling out of favor due to significant treatment failure, high cost, and long duration of treatment. Other antifungal agents have been researched as an alternative to griseofulvin. This paper will review the relevant pharmacologic properties, dosing, cost, efficacy, and ad… Show more

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Cited by 33 publications
(35 citation statements)
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“…For tinea capitis due to M. canis, griseofulvine is the recommended treatment with a response rate up to 88% [34,41,42]. Similar to other European countries, griseofulvine is no longer available in Romania, and therapeutic failure with terbinafine and itraconazole has been reported by authors from other countries [12,13,43].…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…For tinea capitis due to M. canis, griseofulvine is the recommended treatment with a response rate up to 88% [34,41,42]. Similar to other European countries, griseofulvine is no longer available in Romania, and therapeutic failure with terbinafine and itraconazole has been reported by authors from other countries [12,13,43].…”
Section: Discussionmentioning
confidence: 99%
“…Anthropophilic, zoophilic, and geophilic sources are known for various dermatophytes. The widespread but uneven distribution of dermatophytes in the world justifies the need for local epidemiological studies [ 9 , 10 ], as it is essential to identify the precise etiological agents for the effective management, treatment, and prevention of dermatophytosis [ 11 , 12 , 13 ]. During recent decades, insufficient studies have been performed and published regarding the ecology, epidemiology, and etiology of dermatophytosis in Romania.…”
Section: Introductionmentioning
confidence: 99%
“…Similar antifungal treatments are used worldwide for the most of them; however, there are some variations and country-specific guidelines should be consulted [ 1 , 9 ]. Most superficial infections caused by dermatophytes are successfully treated with terbinafine [ 1 , 12 ]. This antimycotic belongs to the allylamine group and is recommended as the first-line oral medication for the treatment of such infections [ 13 15 ].…”
Section: Introductionmentioning
confidence: 99%
“…Most superficial infections caused by dermatophytes are successfully treated with terbinafine. 33,34 This antimycotic belongs to the allylamine group and is recommended as the first-line medication for the treatment of such infections and even sporotrichosis. 35,36 However, to the best of our knowledge, terbinafine resistance in T. mentagrophytes isolates and closely related…”
Section: Discussionmentioning
confidence: 99%