Treatment of the Respiratory Paralysis of Poliomyelitis in a Respiratory Chamber

Shambaugh, G. E.; Harrison, W. G.; Farrell, James I.

doi:10.1001/jama.1930.02710440009004

Cited by 21 publications

(2 citation statements)

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“…Reduction in pulmonary compliance has been observed in anesthetized dogs and on excised dogs' lungs; such changes could be prevented if the lungs were occasionally stretched by means of a deep breath (4). The use of occasional deep breaths was recommended in one of the earliest reports on the treatment of patients with respiratory muscle paralysis (5) and clinical observations on the vital capacity of patients with moderate residual respiratory muscle! weakness due to poliomyelitis have shown that the vital capacity is increased by a series of assisted maximal inspirations (6).…”

mentioning

confidence: 99%

Effect of Deep and Quiet Breathing on Pulmonary Compliance in Man*†

Ferris¹,

Pollard²

1960

J. Clin. Invest.

149

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mentioning

confidence: 99%

Effect of Deep and Quiet Breathing on Pulmonary Compliance in Man*†

Ferris¹,

Pollard²

1960

J. Clin. Invest.

149

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“…6 Approaches might include the use of a gas mixture containing air during induction of anesthesia. 7 Alternatively, re-expansion by hyperinflation should be considered to eliminate atelectasis during GA. 8,9 In this study, the PaO 2 /FIO 2 ratio was used to estimate the extent of impaired gas exchange during GA, 10 since absolute PaO 2 values obtained at different FIO 2 cannot be compared. Atelectasis results in intrapulmonary shunting and mismatching of ventilation/perfusion (V A /Q), leading to impaired gas exchange.…”

Section: Me Et Th Ho Od Ds S Following Approval From the Institutiomentioning

confidence: 99%

Oxygen in air (FiO2 0.4) improves gas exchange in young healthy patients during general anesthesia

Agarwal

Singh

Dhiraj

et al. 2002

Can J Anesth/J Can Anesth

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P Pu ur rp po os se e: : One hundred percent O 2 is used routinely for preoxygenation and induction of anesthesia. The higher the O 2 concentration the faster is the development of atelectasis, an important cause of impaired pulmonary gas exchange during general anesthesia (GA). We evaluated the effect of ventilation with 0.4 FIO 2 in air, 0.4 FIO 2 in N 2 O and 100% O 2 following intubation on the development of impaired gas exchange.M Me et th ho od ds s: : Twenty-seven patients aged 18-40 yr, undergoing elective laparoscopic cholecystectomy were administered 100% O 2 for preoxygenation (three minutes) and ventilation by mask (two minutes). Following intubation these patients were randomly divided into three groups of nine each and ventilated either with 0.4 FIO 2 in air, 0.4 FIO 2 in N 2 O or 100% O 2 . Arterial blood gases were obtained before preoxygenation and 30 min following intubation for PaO 2 analysis. Subsequently PaO 2 /FIO 2 ratios were calculated. Results were analyzed with Student's t test and one-way ANOVA. P value of # 0.05 was considered significant. R Re es su ul lt ts s: : Ventilation of the lungs with O 2 in air (FIO 2 0.4) significantly improved the PaO 2 /FIO 2 ratio from baseline, while 0.4 FIO 2 in N 2 O or 100% O 2 worsened the ratio (558 ± 47 vs 472 ± 28, 365 ± 34 vs 472 ± 22 and 351 ± 23 vs 477 ± 28 respectively; P < 0.05).C Co on nc cl lu us si io on n: : Ventilation of lungs with O 2 in air (FIO 2 0.4) improves gas exchange in young healthy patients during GA. 'ont altéré (558 ± 47vs 472 ± 28, 365 ± 34 vs 472 ± 22 et 351 ± 23 vs 477 ± 28 respectivement; P < 0,05 ENERAL anesthesia (GA) per-se with or without paralysis causes impairment in gas exchange with decreased blood oxygenation. [1][2][3] Atelectasis is an important cause of this impairment in gas exchange during GA. Atelectasis is caused by two mechanisms and both must be present to produce collapse. The two mechanisms are: loss of respiratory muscle tone causing reduction in functional residual capacity (FRC) and resorption of gases. An alveolus or a lung region that is closed off from the ambient air slowly collapses because of absorption of oxygen (O 2 ) into the blood stream whereas carbon dioxide (CO 2 ) delivered to the closed unit will dissolve in the surrounding tissue. The 1040 GENERAL ANESTHESIA

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The Treatment of Respiratory Arrest in the Drinker Respirator

Murphy¹

1931

Arch Intern Med (Chic)

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Treatment of the Respiratory Paralysis of Poliomyelitis in a Respiratory Chamber

Cited by 21 publications

References 1 publication

Effect of Deep and Quiet Breathing on Pulmonary Compliance in Man*†

Effect of Deep and Quiet Breathing on Pulmonary Compliance in Man*†

Oxygen in air (FiO2 0.4) improves gas exchange in young healthy patients during general anesthesia

The Treatment of Respiratory Arrest in the Drinker Respirator

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