Treatment of Striae Distensae Using an Ablative 10,600-nm Carbon Dioxide Fractional Laser

Lee, Sang Eun; Kim, Jong Hoon; Lee, Sang Ju; Lee, Jung Eun; Kang, Jin Moon; Kim, Young Koo; Bang, Dongsik; Cho, Sung Bin

doi:10.1111/j.1524-4725.2010.01719.x

Cited by 83 publications

(88 citation statements)

References 31 publications

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“…They found that the laser was effective in decreasing the size of the striae, a finding that we did not report. Lee et al [17] studied the effect of a fractional CO 2 laser on 27 female patients with skin type IV who had striae alba. They concluded that the laser had a positive therapeutic effect.…”

Section: Discussionmentioning

confidence: 99%

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Histological and quantitative morphometric evaluation of striae distensae treated by long-pulsed 1064-nm Nd

El-Ramly¹,

El-Hanafy²,

Maadawi³

et al. 2015

Journal of the Egyptian Womenʼs Dermatologic Society

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BackgroundStriae distensae are frequent undesirable skin lesions that result in considerable esthetic concern. Treatment has always been challenging. Several modalities are available; however, none of them is consistently effective. Laser has become a popular therapeutic alternative. ObjectiveThe aim of this study was to evaluate the possible therapeutic effect of a long-pulsed 1064 nm Nd:YAG laser in striae distensae using histological and quantitative morphometric studies. Patients and methods Forty female patients with striae (group I: striae rubra and group II: striae alba) were included. All patients received four laser sessions at 4-week intervals. Three skin biopsies were obtained from every patient: one from normal control skin, the second from the selected striae before treatment, and the third from the same striae 1 month after treatment. Paraffin-embedded skin sections were subjected to histological and quantitative morphometric studies for assessment of collagen and elastic fibers. ResultsIn both groups, some clinical improvement was achieved, which was statistically nonsignificant. However, histological examination showed increased collagen and decreased elastic fibers with reorganization after treatment. The image analyzer showed a significant quantitative increase in the mean area percent of collagen fibers and decrease in the mean area percent of elastic fibers. Side effects were nonsignificant, mostly pain during the session and pigmentary alterations. ConclusionAlthough the clinical improvement in the treated striae was nonsignificant, the histological improvement was significant, with few side effects. The use of different laser parameters with a long follow-up period may improve the clinical response.

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Section: Discussionmentioning

confidence: 99%

“…Several studies have investigated the possible therapeutic and beneficial effects of different types of laser in the treatment of striae distensae [12,[15][16][17][18][19].…”

Section: Discussionmentioning

confidence: 99%

Histological and quantitative morphometric evaluation of striae distensae treated by long-pulsed 1064-nm Nd

El-Ramly¹,

El-Hanafy²,

Maadawi³

et al. 2015

Journal of the Egyptian Womenʼs Dermatologic Society

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“…7 Since, as mentioned, stretch marks are thought to be dermal scars, CO 2 FL could theoretically be helpful. Lee et al 8 reported that of 27 patients treated with ablative CO 2 FL, 59% showed marked to near-total improvement. Shin et al 9 also reported that ablative CO 2 FL was effective.…”

Section: Discussionmentioning

confidence: 99%

“…We also observed more side effects of treatment than the previous studies. Lee et al 8 state that only a few patients had mild post-therapy hyperpigmentation. However, in our study, 53.8% of patients had post-therapy hyperpigmentation.…”

Section: Discussionmentioning

confidence: 99%

Comparative Study of the Use of Ablative CO2 Fractional Laser and Ablative Er:YAG Fractional Laser on Striae Distensae in Asian Women

Kim

Park

et al. 2013

Medical Lasers

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Background and ObjectivesTreatment outcomes for striae distensae (SD) vary according to the modalities employed. Although the non-ablative fractional laser (FL) is reported to be effective in the treatment of SD, there has been no comparative study of the efficacies of ablative CO 2 and ablative Er:YAG fractional lasers. The aim of this study was to compare the clinical efficacy and patient satisfaction of these two laser treatments for SD associated with pregnancy. Materials and MethodsThirteen Korean women presenting with pregnancy-associated SD were treated with ablative CO 2 FL on one side and ablative Er:YAG FL on the other. All patients underwent at least two laser treatments at 4-week intervals. Two independent clinicians, blinded to the study details, evaluated clinical efficacy, and subjective satisfaction was assessed on a visual assessment scale (VAS). Side effects of treatment were determined 4 weeks after the last session of treatment. ResultsMean evaluation scores recorded by physicians were low: 1.38 for CO 2 FL and 1.54 for Er:YAG FL (p=0.62). Mean VAS values were 2.08 and 2.15, respectively (p=0.86). There was no statistically significant difference between the clinical scores of two laser devices. Nine patients (69.2%) reported side effects including hyperpigmentation (7 patients) and pain (4 patients). Side effects were more often with ablative CO 2 FL than Er:YAG FL. ConclusionOur study revealed that clinical efficacies of both ablative FL on the treatment of SD were lower than that of previous reports. There was no significant difference between two lasers in clinical efficacy. And Er:YAG seemed to be more safe than CO 2 FL. Further studies are needed to optimize treatment protocol according to the patients' skin type of laser parameters.

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“…Microdermabrasion can be a useful therapeutic option with a possible stimulatory effect on type I procollagen formation [8]. Several light and laser modalities such as intense pulsed light [9], pulsed dye laser [10], copper bromide laser [11], radiofrequency device [12], excimer laser [13], and fractional CO 2 laser [14] have been demonstrated to achieve some effect in treating striae distensae; however, postinflammatory hyperpigmentation is of major concern in darker skin types.…”

Section: Introductionmentioning

confidence: 99%

Microneedling system alone versus microneedling system with trichloroacetic acid in the management of abdominal striae rubra

Sanad¹,

Aginaa²,

Sorour³

2015

Journal of the Egyptian Womenʼs Dermatologic Society

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BackgroundStriae distensae or stretch marks, although not a health risk, are of significant cosmetic concern as it affects the patient's psychological condition. Although many treatment modalities have been attempted with variable results, there is no standard treatment modality for it. Objective To compare the efficacy of a microneedling system (dermaroller) when used alone or combined with 15-30% trichloroacetic acid (TCA) in the management of striae rubra. Patients and methodsThis clinical trial included 30 female patients with abdominal striae rubra treated with a dermaroller alone on the left side of the abdomen (GI) and with a dermaroller + 15-30% TCA on the right side of the abdomen (GII). Patients were treated for six sessions at 3-week intervals. We assessed the clinical features (length, width, color, and texture) of striae in each group at every session and 3 weeks after the end of the sessions (follow-up). The response to treatment was assessed objectively by the treating physicians and skin biopsies stained with hematoxylin and eosin and picrosirius red stains. Subjective assessment of the clinical photographs and patient satisfaction scores was carried out by two uninvolved blind dermatologists at every session. Results A comparison between GI and GII at the follow-up session revealed statistically significant differences in length (P = 0.002), width (Po0.001), color, and texture (P = 0.049 and 0.041, respectively). More improvement in the striae was noted in GII, as 19 (63.3%) patients showed good to excellent improvement compared with 10 (33.3%) patients in GI. Skin biopsies in GII showed increased epidermal thickness after treatment (Po0.005). Collagen content was increased after treatment in both groups. Side effects including transient erythema, edema, burning pain, and hyperpigmentation were observed more in GII with increasing concentration of TCA peeling. ConclusionBoth dermaroller and dermaroller + 15-30% TCA are effective treatment modalities for striae rubra. However, dermaroller + 15-30% TCA gives better results and dermaroller alone has fewer side effects.

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Treatment of Striae Distensae Using an Ablative 10,600-nm Carbon Dioxide Fractional Laser

Abstract: Our observations demonstrated that the use of CO₂ FS can have a positive therapeutic effect on late-stage striae distensae.

Cited by 83 publications

References 31 publications

Histological and quantitative morphometric evaluation of striae distensae treated by long-pulsed 1064-nm Nd

Histological and quantitative morphometric evaluation of striae distensae treated by long-pulsed 1064-nm Nd

Comparative Study of the Use of Ablative CO2 Fractional Laser and Ablative Er:YAG Fractional Laser on Striae Distensae in Asian Women

Microneedling system alone versus microneedling system with trichloroacetic acid in the management of abdominal striae rubra

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