Treatment of Squamous Cell Carcinoma of the Skin

Honeycutt, W M; Jansen, G. Thomas

doi:10.1001/archderm.1973.01620260020006

Cited by 54 publications

(17 citation statements)

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“…554,587,606,609 Increased lesion size as a significant prognostic feature was observed in one study and recurrence in the 17 SCCs > 2 cm was 11.8% (95% CI 1.4% to 36.4%) compared with 0.4% (95% CI 0.0% to 2.1%) in the 264 SCCs < 2 cm. 587 One study separated results according to the number of treatment cycles used with no recurrences after either two or three cycles. 606 Two studies specified the number of cycles of electrodesiccation as either double 607 or triple, 608 but this information was not reported for the remaining studies.…”

Section: Curettage and Electrodesiccationmentioning

confidence: 97%

“…542,547,554,[581][582][583][584][585][586][587][588][589][590][591] Seven studies (comprising 761 patients) reported local recurrence after external radiotherapy, with pooled average local recurrence of 6.4% (95% CI 3.0% to 11.0%; I 2 = 76%) 542,547,581,582,584,585,591 (see Appendix 8 and Figure 40). Three studies were included in the sensitivity analysis, 582,585,591 with no significant effect on local recurrence (7.3%, 95% CI 2.1% to 15.4%; I 2 = 87%).…”

Section: External Radiotherapymentioning

confidence: 99%

“…554,583,[587][588][589][590] Pooled data from the 220 treated SCCs from the studies gave an average recurrence of 4.8% (95% CI 0.6% to 12.8%; I 2 = 70%) ( Figure 42).…”

Section: Squamous Cell Skin Cancer Work Programmementioning

confidence: 99%

“…Average recurrence in the two studies with specified mean duration of follow-up of between 2 and 5 years was 6.1% (44 patients, 95% CI 0% to 22.6%). 587,589 There were no studies in which the mean follow-up period was > 5 years, with unspecified mean follow-up duration in the remaining two studies. DOI: 10.3310/pgfar04180 PROGRAMME GRANTS FOR APPLIED RESEARCH 2016 VOL.…”

Section: Squamous Cell Skin Cancer Work Programmementioning

confidence: 99%

“…554,557,587,[606][607][608][609] On pooled analysis, average recurrence was 1.7% (95% CI 0.6% to 3.4%; I 2 = 59%) ( Figure 45). We did not perform a sensitivity analysis as none of the studies met the criteria for this.…”

Section: Curettage and Electrodesiccationmentioning

confidence: 99%

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A programme of research to set priorities and reduce uncertainties for the prevention and treatment of skin disease

Kim

Batchelor

Bath‐Hextall

et al. 2016

Programme Grants Appl Res

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Programme Grants for Applied ResearchISSN 2050-4322 (Print) ISSN 2050-4330 (Online) This journal is a member of and subscribes to the principles of the Committee on Publication Ethics (COPE) (www.publicationethics.org/).Editorial contact: nihredit@southampton.ac.ukThe full PGfAR archive is freely available to view online at www.journalslibrary.nihr.ac.uk/pgfar. Print-on-demand copies can be purchased from the report pages of the NIHR Journals Library website: www.journalslibrary.nihr.ac.uk Criteria for inclusion in the Programme Grants for Applied Research journalReports are published in Programme Grants for Applied Research (PGfAR) if (1) they have resulted from work for the PGfAR programme, and (2) they are of a sufficiently high scientific quality as assessed by the reviewers and editors. Programme Grants for Applied Research programmeThe Programme Grants for Applied Research (PGfAR) programme, part of the National Institute for Health Research (NIHR), was set up in 2006 to produce independent research findings that will have practical application for the benefit of patients and the NHS in the relatively near future. The Programme is managed by the NIHR Central Commissioning Facility (CCF) with strategic input from the Programme Director.The programme is a national response mode funding scheme that aims to provide evidence to improve health outcomes in England through promotion of health, prevention of ill health, and optimal disease management (including safety and quality), with particular emphasis on conditions causing significant disease burden.For more information about the PGfAR programme please visit the website: http://www.nihr.ac.uk/funding/programme-grants-forapplied-research.htm This reportThe research reported in this issue of the journal was funded by PGfAR as project number RP-PG-0407-10177. The contractual start date was in September 2008. The final report began editorial review in April 2014 and was accepted for publication in April 2016. As the funder, the PGfAR programme agreed the research questions and study designs in advance with the investigators. The authors have been wholly responsible for all data collection, analysis and interpretation, and for writing up their work. The PGfAR editors and production house have tried to ensure the accuracy of the authors' report and would like to thank the reviewers for their constructive comments on the final report document. However, they do not accept liability for damages or losses arising from material published in this report.This report presents independent research funded by the National Institute for Health Research (NIHR). The views and opinions expressed by authors in this publication are those of the authors and do not necessarily reflect those of the NHS, the NIHR, CCF, NETSCC, PGfAR or the Department of Health. If there are verbatim quotations included in this publication the views and opinions expressed by the interviewees are those of the interviewees and do not necessarily reflect those of the authors, those of the NHS, the NIHR, ...

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Section: Curettage and Electrodesiccationmentioning

confidence: 97%

Section: External Radiotherapymentioning

confidence: 99%

“…554,583,[587][588][589][590] Pooled data from the 220 treated SCCs from the studies gave an average recurrence of 4.8% (95% CI 0.6% to 12.8%; I 2 = 70%) ( Figure 42).…”

Section: Squamous Cell Skin Cancer Work Programmementioning

confidence: 99%

Section: Squamous Cell Skin Cancer Work Programmementioning

confidence: 99%

Section: Curettage and Electrodesiccationmentioning

confidence: 99%

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