Treatment of simple bone cysts of the humerus by intramedullary nailing and steroid injection

Zhang, Peng; Zhu, Naiqiang; Du, Lilong; Zheng, Jihui; Hu, Sibin; Xu, Baoshan

doi:10.1186/s12891-020-3054-6

Cited by 21 publications

(25 citation statements)

References 37 publications

(36 reference statements)

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“…among them are intramedullary nailing and steroid injection [5], injection of bioabsorbable bone cement [6] and artificial bone substitutes [7]. However, so far there is no evidence to determine the best method for treatment [8].…”

Section: Discussionmentioning

confidence: 99%

Treatment of Unicameral and Aneurysmal Bone Cysts by Minimally Invasive Percutaneous Injection of Grafton DBF Putty Using the Kyphon Cement Delivery System

Exner¹,

Schai²

2020

OJO

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Background: Simple Unicameral and Aneurysmal Bone Cysts are benign lesions that may heal spontaneously especially after fracture which may be the first symptom. However, often size increases causing pain, and complications of fractures can severely compromise the patient. Aim: The results in a series of cases treated minimally invasive using a new device for the application of allogenic bone material appear highly promising and shall be presented. Patients and Methods: Eight consecutive patients with symptomatic Unicameral Bone Cysts (UBC) were treated by percutaneous instillation of Grafton  DBF Putty (demineralised allogenic bone containing fibers) mixed with autologous bone marrow using the Kyphon  Cement Delivery System (Medtronic), which allows the injection of this high viscosity paste by controlled high pressure. Five patients with Aneurysmal Bone Cysts (ABC) were treated accordingly after inactivation by Aethoxysclerol 3% and lacking bone formation. Using this approach a high rate of bone regeneration was observed in these patients at 8 months to 5 years follow-up (f/u). Conclusion: The presented technique of a minimally invasive biologic treatment led to highly satisfying results using the Grafton  DBF Putty with its higher potential for bone regeneration than demineralized bone matrix not containing fibres (DBM).

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Section: Discussionmentioning

confidence: 99%

Treatment of Unicameral and Aneurysmal Bone Cysts by Minimally Invasive Percutaneous Injection of Grafton DBF Putty Using the Kyphon Cement Delivery System

Exner¹,

Schai²

2020

OJO

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“…The boundary of the cyst is clear and sharp, mostly with the thin-wall sclerotic edge. Bone debris collapse sign can be found when pathological fracture happens [ 1 , 13 ].…”

Section: Methodsmentioning

confidence: 99%

“…The unicameral bone cyst (UBC) is a kind of benign tumor that usually occurs in the epiphysis of the long diaphysis [ 1 – 3 ]. The etiology and pathogenesis of UBC in children have not been identified [ 3 ].…”

Section: Introductionmentioning

confidence: 99%

Comparison of three treatment methods for simple bone cyst in children

Zhang

Chai

Zhao

et al. 2021

BMC Musculoskelet Disord

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Background The unicameral bone cyst (UBC) is a kind of benign tumor whose clinical treatments and efficacy are controversial. The purpose of this study was to evaluate the efficacy of the elastic stable intramedullary nail (ESIN), the injection of autologous bone marrow (ABM), and the combination of ESIN and ABM in the treatment of bone cyst in children. Methods Eighty-three cases with simple bone cyst were analyzed retrospectively. Twenty-eight cases were treated with ABM. Twenty-eight cases were treated with ESIN. Twenty-seven cases were treated with ABM and ESIN. All cases were diagnosed through X-ray, CT, or MRI scans. For the suspicious ones, the pathological biopsy was performed for an accurate diagnosis. X-ray examinations were carried out for the postoperative follow-up. Capanna criteria for bone cyst was used for postoperative evaluation of three methods. Results All cases accomplished the follow-up. The effective rate of the ABM + ESIN group was significantly higher than that of the ABM group (P < 0.05), and the cure rates of the ESIN group and the ABM + ESIN group were higher than that of the ABM group (P < 0.05, respectively). The cure time in the ESIN group was lower than that of the other two groups (P < 0.05, respectively). The times for admission were 2.0 ± 0.0 in the ESIN group, 5.7 ± 1.9 in the ABM group, and 4.7 ± 2.4 in the ABM + ESIN group (P < 0.05 when compared with each other). Conclusions The method of ABM combined with ESIN for children’s bone cyst has the highest effective rate and curative rate. For the individual method, ESIN has a higher effective rate and curative rate than that of ABM. Meanwhile, it has the fewest time of hospitalization.

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“…The unicameral bone cyst (UBC) is a kind of benign tumor that usually occurs in the epiphysis of the long diaphysis [1][2][3] . The etiology and pathogenesis of UBC in children have not been identi ed 3 .…”

Section: Introductionmentioning

confidence: 99%

Comparison of three treatment methods for simple bone cyst in children

Zhang

Chai

Zhao³

et al. 2021

Preprint

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Background The unicameral bone cyst (UBC) is a kind of benign tumor whose clinical treatments and efficacy are controversial. The purpose of this study was to evaluate the efficacy of the elastic stable intramedullary nail (ESIN), the injection of autologous bone marrow (ABM), and the combination of ESIN and ABM in the treatment of bone cyst in children. Methods 83 cases with simple bone cyst were analyzed retrospectively. 28 cases were treated with ABM. 28 cases were treated with ESIN. 27 cases were treated with ABM and ESIN. All cases were diagnosed through X-ray, CT, or MRI scans. For the suspicious ones, the pathological biopsy was performed for an accurate diagnosis. X-ray examinations were carried out for the postoperative follow-up. Capanna criteria for bone cyst was used for postoperative evaluation of three methods. Results All cases accomplished the follow-up. The effective rate of the ABM+ESIN group was significantly higher than that of the ABM group (P<0.05), and the cure rates of the ESIN group and the ABM+ESIN group were higher than that of the ABM group (P<0.05, respectively). The cure time in the ESIN group was lower than that of the other two groups (P<0.05, respectively). The times for admission were 2.0±0.0 in the ESIN group, 5.7±1.9 in the ABM group, and 4.7±2.4 in the ABM+ESIN group (P<0.05 when compared with each other). Conclusions The method of ABM combined with ESIN for children’s bone cyst has the highest effective rate and curative rate. For the individual method, ESIN has a higher effective rate and curative rate than that of ABM. Meanwhile, it has the fewest time of hospitalization.

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Treatment of simple bone cysts of the humerus by intramedullary nailing and steroid injection

Cited by 21 publications

References 37 publications

Treatment of Unicameral and Aneurysmal Bone Cysts by Minimally Invasive Percutaneous Injection of Grafton DBF Putty Using the Kyphon Cement Delivery System

Treatment of Unicameral and Aneurysmal Bone Cysts by Minimally Invasive Percutaneous Injection of Grafton DBF Putty Using the Kyphon Cement Delivery System

Comparison of three treatment methods for simple bone cyst in children

Comparison of three treatment methods for simple bone cyst in children

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