Treatment of recurrent gynecologic malignancies with iodine-125 permanent interstitial irradiation

Monk, Bradley J.; Tewari, Krishnansu S.; Puthawala, Ajmel; Syed, A.M. Nisar; Haugen, Julie A.; Burger, Robert A.

doi:10.1016/s0360-3016(01)02728-6

Cited by 42 publications

(30 citation statements)

References 38 publications

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“…An isodose curve and dose-volume histogram were drawn to concentrate the radioactivity in the target area. The expected number of implanted seeds was then calculated according to the modified Cevec formula (Monk et al, 2002) as follows: Number of seeds needed…”

Section: Calculation Of the Number Of Seeds Needed For Implantationmentioning

confidence: 99%

“…In brief, the information from CT or MRI images was reconstructed into a three-dimensional form, and the precise margin of the tumor was outlined to facilitate the calculation of tumor matched peripheral dose (MPD). The expected number of implanted seeds was calculated according to the modified level formula (Monk et al, 2002). In practice, to reach the maximum radiation effect, the number of seeds implanted was 15% more than needed.…”

Section: Ct-guided Interstitial Brachytherapy Protocolmentioning

confidence: 99%

“…Also EBRT alone has failed to control disease progression and yields a median survival of 5.5-7 months (Bodner et al, 2000;Nag et al, 2006). The introduction of intraoperative electron beam radiotherapy, combined with EBRT and chemotherapy, has also failed to significantly improve long-term results, with recent studies reporting median survival rates of 7-16 months (Blasko et al, 2002;Cengiz et al, 2008;Monk et al, 2002). Despite the availability of many treatments, there was currently no consensus regarding the optimal therapeutic modality for unresectable pancreatic carcinomas.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Clinical Application of Image-Guided Iodine-125 Seed Implantation Therapy in Patients with Advanced Pancreatic Cancer

Wang¹,

Chen²

2011

Current Cancer Treatment - Novel Beyond Conventional Approaches

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Section: Calculation Of the Number Of Seeds Needed For Implantationmentioning

confidence: 99%

Section: Ct-guided Interstitial Brachytherapy Protocolmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Clinical Application of Image-Guided Iodine-125 Seed Implantation Therapy in Patients with Advanced Pancreatic Cancer

Wang¹,

Chen²

2011

Current Cancer Treatment - Novel Beyond Conventional Approaches

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“…Women with noncentral tumor recurrences have a worse prognosis than those with an isolated vaginal relapse. Although only limited experience exists, salvage radiation therapy may be appropriate in the setting of a noncentral recurrence [12]. For women with a pelvic recurrence, the 3-year survival rate is reported to be 8%, compared with 73% for those with an isolated vaginal recurrence [4,5].…”

Section: Radiation Therapy For Locally Recurrent Endometrial Cancermentioning

confidence: 99%

Treatment for Advanced and Recurrent Endometrial Carcinoma: Combined Modalities

Rauh‐Hain

Carmen

2010

The Oncologist

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After completing this course, the reader will be able to:1. Discuss the role of radiation therapy for advanced stage endometrial cancer in order to differentiate between patients who should receive only radiation therapy and patients requiring surgery and/or chemotherapy in addition to radiation.2. Evaluate the role of surgery for stage IV and recurrent endometrial cancer in order to select patients most likely to benefit from cytoreductive surgery.3. Evaluate the role of chemotherapy, particularly in conjunction with radiotherapy, in advanced stage endometrial carcinoma and select appropriate candidates for multimodality therapy.This article is available for continuing medical education credit at CME.TheOncologist.com. CME CME ABSTRACTWomen with recurrent or advanced endometrial cancer constitute a heterogeneous group of patients. Depending on previous treatment, women with recurrent endometrial cancer may be appropriate candidates for surgery, radiation therapy, hormonal therapy, or chemotherapy. Women with advanced stage disease at presentation may also be appropriate candidates for systemic and local therapies. We review the treatment options available to treat recurrent and locally advanced endometrial cancer. Treatment choice depends largely on the localization of disease, the patient's performance status and previ-

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“…In combination of these two therapies sometimes intraoperative electron beam radiotherapy is also used but unsatisfactory outcomes are found [15][16][17][18][19]. Though this combination relieves pain to the significant level but has severe effects on patient's body and increase only median survival rates.…”

Section: Introductionmentioning

confidence: 99%

Radiotherapy is One of the Effective and Common Measures of Pancreatic Cancer Therapy: Iodine-125 (125i) Brachytherapy Improves Local Control and Increase Survival

Ramzan¹,

Lateef²,

Zaman³

2018

Chemotherapy

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Introduction: The malignant tumors of torment and life taking pancreatic cancer account for adeno-carcinoma which finds its origin in the exocrine secretions of pancreas. Though a lot many techniques and methodologies are surfacing in the field of medical science but still the overall survival rate is not remarkable. The recommended treatment for local tumor control is the implantation of the I125 radioactive seed (brachytherapy) in the effected organ.

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Treatment of recurrent gynecologic malignancies with iodine-125 permanent interstitial irradiation

Cited by 42 publications

References 38 publications

Clinical Application of Image-Guided Iodine-125 Seed Implantation Therapy in Patients with Advanced Pancreatic Cancer

Clinical Application of Image-Guided Iodine-125 Seed Implantation Therapy in Patients with Advanced Pancreatic Cancer

Treatment for Advanced and Recurrent Endometrial Carcinoma: Combined Modalities

Radiotherapy is One of the Effective and Common Measures of Pancreatic Cancer Therapy: Iodine-125 (125i) Brachytherapy Improves Local Control and Increase Survival

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