Treatment of Pigmented Villonodular Synovitis of the Knee

IT-based Psychosocial Distress Screening in Patients with Sarcoma and Parental Caregivers via Disease-specific Online Social Media Communities

“…A large study cohort was generated despite the low percentage of participants (26.3%) compared with 1112 group members. In contrast, recent studies using conventional recruitment strategies showed significantly smaller cohorts (25,26). Similarly, in the present study, we enrolled 28 patients with OS or ES and 58 parents of patients with OS or ES in only 2 months.…”

Treatment of PVNS of the Knee

“…We were very pleased to read the work of Aurégan et al, "Treatment of Pigmented Villonodular Synovitis of the Knee," published in the October issue of Arthroscopy. 1 Reviewing the literature ourselves we noticed that there are plenty of studies reporting the results of series with a limited number of patients. This is normal because PVNS is a rare disease and a review and meta-analysis of the existing literature is a validated method of drawing conclusions from larger number of patients.…”

“…Given the fact that Dines et al reported the recurrence rate after surgical excision of localized pigmented villonodular synovitis (LPVNS) at a follow-up greater than 1 year, their study met our inclusion criteria. 1 Being aware that only a part of the original series was available for long-term results, we displayed…”

Diagnostic Imaging and Management of Common Intra-articular and Peri-articular Soft Tissue Tumors and Tumorlike Conditions of the Knee

“…34 There seems to be no gender predilection, and it most commonly affects patients in their twenties to forties. 35,36 PVNS is described as two different types: the localized form (LPVNS) is a solitary pedunculated lesion, also referred to as focal nodular synovitis, whereas the diffuse form (DPVNS) involves the entire joint. 34 PVNS is considered a benign but locally aggressive process that can lead to significant joint destruction over time.…”

“…34 The aim of treatment is removal of all involved abnormal tissue to relieve pain, decrease recurrence risk, and diminish joint destruction. 35 Surgical resection remains the mainstay of treatment, and although radiation has been shown to diminish recurrence in refractory disease, 34 it alone is not superior to surgery. 38 LPVNS is often treated with arthroscopic excision, with reports of 0 to 8% recurrence.…”