“…Conservative treatment has traditionally been the primary therapeutic approach to NHNA and a number of different agents and modalities has been reported through years ( Table 2 ) [4] , [5] , [6] , [7] , [8] , [9] , [10] , [11] , [12] , [13] , [14] , [15] . Success rates, however, have varied greatly: early results have been usually acceptable (except for etretinate) [16] , but the final esthetic outcome was often not so satisfactory, and longer follow-up were either not available or showed recurrences after cessation [5] , [8] , [10] .…”