Treatment of Neonatal Chlamydial Conjunctivitis With Azithromycin

Chlamydia trachomatis as a Cause of Neonatal Conjunctivitis in Dutch Infants

“…We recommend that confirmed chlamydial conjunctivitis should be treated systemically with erythromycin suspension or alternatively azithromycin. 13,25 Current national treatment guidelines for neonatal chlamydial conjunctivitis are from the Health Care Insurance Board and recommend tetracycline eye drops (with or without oral erythromycin or tetracycline). 26 The current Centers for Disease Control and Prevention recommendation, however, is to treat all neonatal chlamydial conjunctivitis systemically with a 14-day course of erythromycin suspension.…”

Tumor Necrosis Factor-α and Interleukin-6 Levels in Patients with Primary Open-Angle Glaucoma

“…Macrolide antibiotics such as azithromycin, clarithromycin and roxithromycin may be more effective against Chlamydial infections [57], but have not been well studied in neonatal Chlamydial conjunctivitis. The results of one study involving a limited number of patients suggest that a short course of azithromycin, 20 mg/kg/day orally, 1 dose daily for 3 days, may be effective [58].…”

“…Alternative therapies include cefotaxime 100mg intramuscularly or 25 mg/kg given either intramuscularly or intravenously every 12 hours for 7 days [58,61].…”

Trachoma and Conjunctivitis

“…Erythromycin, azithromycin and clarithromycine may be effective for halting transmission to the baby and treating neonatal conjunctivitis. 41,42 Prophylaxis, however, may be ineffective in some new born patients. Erythromycin base or ethyl succinate 50 mg/kg/day may be given orally divided into four doses daily for 14 days.…”