Treatment of moderate obstructive sleep apnea syndrome with acupuncture: A randomised, placebo-controlled pilot trial

Freire, Anaflávia O; Sugai, Gisele C.M.; Chrispin, Fernanda Silveira; Togeiro, Sônia Maria; Yamamura, Ysao; Mello, Luiz E.; Tufik, Sérgio

doi:10.1016/j.sleep.2006.04.009

Cited by 42 publications

(49 citation statements)

References 27 publications

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“…In a previous study our group showed that MA was effective in providing significant changes in polysomnographic evaluations as well as in the quality of life of patients with OSA after 10 weekly sessions of acupuncture. 9 The speculative hypothesis for this improvement was the involvement of serotonergic pathways 22 23 in the responses mediated by acupuncture as well as its anti-infl ammatory effect. 24 Electrical acupoint stimulation has been widely used as a substitute for classical acupuncture.…”

Section: Discussionmentioning

confidence: 99%

Immediate Effect of Acupuncture on the Sleep Pattern of Patients with Obstructive Sleep Apnoea

et al. 2010

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Background Most patients with obstructive sleep apnoea (OSA) do not tolerate treatment with nasal continuous positive airway pressure, the 'gold standard' treatment for this condition. It was shown in a pilot study that acupuncture was more effective than placebo treatment (sham acupuncture) in producing signifi cant changes in the respiratory events assessed by polysomnography (PSG). Objectives To investigate the immediate effect of manual acupuncture (MA) and electroacupuncture (EA) on the sleep pattern of patients presenting with moderate OSA. Methods 40 patients with an Apnoea-Hypopnoea Index (AHI) of 15-30/h were randomly allocated to MA treatment (n=10), EA 10 Hz treatment (n=10), EA 2 Hz treatment (n=10) and a no-treatment control group (n=10). The patients received MA or EA (2 or 10 Hz) just before the PSG study at 20:00. Results The AHI (p=0.005; p=0.005), the Apnoea Index (p=0.038; p=0.009) and the respiratory events (p=0.039; p=0.014) decreased signifi cantly in the MA and EA 10 Hz groups, respectively (AHI (21.9, 11.2), Apnoea Index (5.15, 0.7), respiratory events (120.5, 61.0) in the MA group before and after. AHI (20.6, 9.9), Apnoea Index (8.2, 0.3), respiratory events (117.0, 56.0) in the EA 10 Hz group before and after). The micro-arousals decreased only in the MA group (146.0 vs 88.5, p=0.0002). There were no signifi cant changes in the EA 2 Hz group or in the control group. Conclusion A single session of either MA or EA 10 Hz had an acute effect in reducing the AHI as well as the number of nocturnal respiratory events of patients presenting with moderate OSA.

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Section: Discussionmentioning

confidence: 99%

Immediate Effect of Acupuncture on the Sleep Pattern of Patients with Obstructive Sleep Apnoea

et al. 2010

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“…Some studies have been performed with the purpose to understand the effects related to inflammatory processes, muscular pain, stress, insomnia, and others (7,(9)(10)(11)(12) .…”

Section: Introductionmentioning

confidence: 99%

“…For instance, a study performed in China demonstrated that electroacupuncture produced better effects than placebo acupuncture in treating this pathology (11) . Also, in Brazil, there is a report of a recent study that shows that acupuncture was more effective in treating Obstructive Sleep Apnea Syndrome compared to placebo acupuncture, which helped improve the quality of life of patients reducing hypersomnia episodes (12) .…”

Section: Introductionmentioning

confidence: 99%

Qualidade de sono de trabalhadores obesos de um hospital universitário: acupuntura como terapia complementar

Haddad

Medeiros

Marcon

2012

Rev. esc. enferm. USP

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O objetivo do estudo foi verificar o efeito da acupuntura na qualidade de sono de trabalhadores obesos em um hospital universitário. Os dados foram coletados no período de julho a outubro de 2009, junto a 37 funcionários, submetidos a oito aplicações semanais de acupuntura. O Índice de Qualidade de Sono de Pittsburgh foi utilizado para identificar a qualidade de sono dos sujeitos antes e após a intervenção. Os resultados mostram que antes da intervenção cinco (13,5%) pessoas apresentaram boa qualidade de sono e, ao final da intervenção, 14 (37,8%) relataram este quadro. A diferença obtida na comparação das médias dos escores obtidos antes e após a acupuntura foi significativa (p=0,0001). Concluiu-se que a acupuntura produziu um efeito positivo sobre a qualidade do sono na amostra estudada, apresentando-se como uma técnica adjuvante no tratamento dos distúrbios do sono e consequentemente na melhoria da qualidade de vida desta população.

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“…25 According to a recent study that used the Oregon CONSORTIUM-STRICTA instrument to evaluate the quality of the acupuncture studies, 26 Brazil had only three studies that reached minimum quality criteria. 20,27,28 The above-mentioned data may also have influenced the Brazilian citation performance and indicate that the acupuncture research community in Brazil needs to discuss strategies to improve the design and reporting of their acupuncture trials. On the basis of the analysis of document type, the proportion of original article and review publications in Brazil is similar to the global proportion of these documents.…”

Section: Discussionmentioning

confidence: 99%

Status and Impact of Acupuncture Research: A Bibliometric Analysis of Global and Brazilian Scientific Output from 2000 to 2014

Moré

Tesser

Silva

et al. 2016

The Journal of Alternative and Complementary Medicine

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Treatment of moderate obstructive sleep apnea syndrome with acupuncture: A randomised, placebo-controlled pilot trial

Cited by 42 publications

References 27 publications

Immediate Effect of Acupuncture on the Sleep Pattern of Patients with Obstructive Sleep Apnoea

Immediate Effect of Acupuncture on the Sleep Pattern of Patients with Obstructive Sleep Apnoea

Qualidade de sono de trabalhadores obesos de um hospital universitário: acupuntura como terapia complementar

Status and Impact of Acupuncture Research: A Bibliometric Analysis of Global and Brazilian Scientific Output from 2000 to 2014

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