Treatment of minor wounds from dermatologic procedures: A comparison of three topical wound care ointments using a laser wound model

Trookman, Nathan S.; Rizer, Ronald L.; Weber, Teresa

doi:10.1016/j.jaad.2010.11.011

Cited by 34 publications

(19 citation statements)

References 15 publications

(16 reference statements)

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“…The mupirocin group showed significantly more cases of skin edge necrosis than the other groups 12 . Similarly, petrolatum-based ointment resulted in better wound outcomes than did antibiotic-containing treatments 24 .…”

Section: Discussionmentioning

confidence: 98%

Retrospective Clinical Trial of Fusidic Acid versus Petrolatum in the Postprocedure Care of Clean Dermatologic Procedures

et al. 2015

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BackgroundClean dermatologic procedures create wounds with a low risk of infection (usually up to 5%). Whether the use of topical antibiotics is advocated, with regard to its efficacy and safety issues such as antibiotic resistance and sensitizing potential, is controversial. Fusidic acid, a topical antibiotic against gram-positive bacteria, is a rare sensitizer and commonly used in postprocedure care in Korea.ObjectiveThis is a retrospective study aimed at comparing the efficacy and safety between fusidic acid and petrolatum for the postprocedure care of clean dermatologic procedures.MethodsPatients were treated with either fusidic acid or petrolatum ointment, applied on the wound created during clean dermatologic procedures such as biopsy of the punch, incisional, excisional, and shave types. The efficacy, adverse events, and subjective level of satisfaction were retrieved from medical records.ResultsA total of 414 patients with a total of 429 wounds were enrolled. The overall rate of adverse events was 0.9%, and the rates of adverse events in the fusidic acid group and the petrolatum group were 1.4% and 0.5%, respectively (p=0.370). There was no wound discharge, pain, tenderness, swelling, induration, or dehiscence in both groups. The patients' self-assessment of the wound was not significantly different between the two treatment groups.ConclusionOur findings support the hypothesis that the routine prophylactic use of topical antibiotics is not indicated for clean dermatologic procedures. We recommend the use of petrolatum in the postoperative care of clean dermatologic procedures because of its equivalent efficacy and superior safety profiles.

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Section: Discussionmentioning

confidence: 98%

Retrospective Clinical Trial of Fusidic Acid versus Petrolatum in the Postprocedure Care of Clean Dermatologic Procedures

et al. 2015

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“…The application of a triple antibiotic ointment is usually started immediately after closure of the wound intraoperatively and continued twice daily for 1 to 3 weeks postoperatively. 16,17 One drawback to the use of these products is the development of contact dermatitis in some patients that is not seen with petroleum jelly ointments. 16 To minimize allergic reaction, some physicians prefer to use an antibiotic ointment for the first week due to its antimicrobial effects then switch to a petroleum jelly ointment for the next 1 to 2 weeks.…”

Section: Postoperative Interventionsmentioning

confidence: 99%

“…Petroleum jelly ointments such as Vaseline (Unilever, Englewood Cliffs, NJ) applied three times daily for 1 to 3 weeks duration or nonadherent petroleum-impregnated gauze such as Xeroform (Kendall/Covidien, Mansfield, MA) placed daily for 1 to 3 weeks are excellent alternatives to maintain wound bed moisture. 17,18 Petroleum jelly has the added benefit of reducing scar erythema. Ointments such as Vaseline provide an affordable option with comparable benefits to other more expensive treatments.…”

Section: Postoperative Interventionsmentioning

confidence: 99%

Update on Postsurgical Scar Management

Commander

Chamata

Cox

et al. 2016

Seminars in Plastic Surgery

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Postoperative scar appearance is often a significant concern among patients, with many seeking advice from their surgeons regarding scar minimization. Numerous products are available that claim to decrease postoperative scar formation and improve wound healing. These products attempt to create an ideal environment for wound healing by targeting the three phases of wound healing: inflammation, proliferation, and remodeling. With that said, preoperative interventions, such as lifestyle modifications and optimization of medical comorbidities, and intraoperative interventions, such as adherence to meticulous operative techniques, are equally important for ideal scarring. In this article, the authors review the available options in postoperative scar management, addressing the benefits of multimodal perioperative intervention. Although numerous treatments exist, no single modality has been proven superior over others. Therefore, each patient should receive a personalized treatment regimen to optimize scar management.

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“…8 Allergic contact dermatitis may not have occurred because of the relatively short duration of the study compared with the longer duration of potential allergen application to chronic wounds. The topical emulsion caused the most irritation, and the topical healing ointment caused the least.…”

Section: Review Of the Current Literaturementioning

confidence: 99%

Wound-Related Allergic/Irritant Contact Dermatitis

Alavi

Sibbald

Ladizinski

et al. 2016

Advances in Skin &Amp; Wound Care

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Contact dermatitis to wound care products is a common, often neglected problem. A review was conducted to identify articles relevant to contact dermatitis.A PubMed English-language literature review was conducted for appropriate articles published between January 2000 and December 2015.Contact dermatitis is both irritant (80% of cases) or allergic (20% of cases). Frequent use of potential contact allergens and impaired barrier function of the skin can lead to rising sensitization in patients with chronic wounds. Common known allergens to avoid in wound care patients include fragrances, colophony, lanolin, and topical antibiotics.Clinicians should be cognizant of the allergens in wound care products and the potential for sensitization. All medical devices, including wound dressings, adhesives, and bandages, should be labeled with their complete ingredients, and manufacturers should be encouraged to remove common allergens from wound care products, including topical creams, ointments, and dressings.

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Treatment of minor wounds from dermatologic procedures: A comparison of three topical wound care ointments using a laser wound model

Cited by 34 publications

References 15 publications

Retrospective Clinical Trial of Fusidic Acid versus Petrolatum in the Postprocedure Care of Clean Dermatologic Procedures

Retrospective Clinical Trial of Fusidic Acid versus Petrolatum in the Postprocedure Care of Clean Dermatologic Procedures

Update on Postsurgical Scar Management

Wound-Related Allergic/Irritant Contact Dermatitis

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