Treatment of lymphogranuloma venereum with rifampicin.

Menke, Henk E.; Schuller, JC; Stolz, E.; Niemel, P L; Michel, Marie-Claude

doi:10.1136/sti.55.5.379

Cited by 5 publications

(6 citation statements)

References 2 publications

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“…In another study of the treatment of nongonococcal urethritis (22), minocycline and rifampin had equal efficacies in eradicating C trachomatis. There are anecdotal reports of the successful treatment of lymphogranuloma venereum (64) and Chlamydia psittaci endocarditis (48).…”

Section: Chlamydlaementioning

confidence: 99%

Use of rifampin in nonstaphylococcal, nonmycobacterial disease

Morris

Brown

Sands

1993

Antimicrob Agents Chemother

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Rifampin has very broad antimicrobial properties with in vitro activities against many bacteria, mycobacteria, higher bacteria, chlamydia, fungi, parasites, and viruses (Table 1). The clinical use of rifampin is more limited, in part because of the lack of in vivo human clinical studies demonstrating its efficacy. Investigators have valid concerns regarding the emergence of resistance of mycobacteria if widespread use of rifampin becomes common, although this has not been well documented. Because rifampin obtains therapeutic levels intracellularly and is distributed widely throughout the body, the antibiotic potentially could be used on a broader scale, but more studies will be needed to demonstrate its clinical utility.

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Section: Chlamydlaementioning

confidence: 99%

Use of rifampin in nonstaphylococcal, nonmycobacterial disease

Morris

Brown

Sands

1993

Antimicrob Agents Chemother

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“…Under the stringent conditions of exposing the cells to antimicrobial agents 48 h after infection, rifampin was, along with doxycycline, the most active agent tested against Chlamydia trachomatis (1). Further investigation of this agent has been hampered by early reports of rapid emergence of resistant strains after multiple passages (9,10,18), and clinical data are scarce (3,8,16). These observations made it unlikely that rifampin monotherapy would be of practical value; therefore, we did not study the effect of rifampin alone in our pneumonitis model.…”

mentioning

confidence: 99%

Effect of Azithromycin plus Rifampin versus That of Azithromycin Alone on the Eradication of Chlamydia pneumoniae from Lung Tissue in Experimental Pneumonitis

Wolf

Malinverni

1999

Antimicrob Agents Chemother

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“…Menke et al . in 1979 reported that rifampicin was also effective in the management of LGV 72 . Reports by Banov also support the clinical usefulness of erythromycin therapy in LGV 73 .…”

Section: Managementmentioning

confidence: 93%

“…Other treatment options include oral sulfadiazine and chloramphenicol. 70,71 Menke et al in 1979 reported that rifampicin was also effective in the management of LGV. 72 Reports by Banov also support the clinical usefulness of erythromycin therapy in LGV.…”

Section: Management Medical Managementmentioning

confidence: 99%

“…70,71 Menke et al in 1979 reported that rifampicin was also effective in the management of LGV. 72 Reports by Banov also support the clinical usefulness of erythromycin therapy in LGV. 73 In fact, oral erythromycin (non-estolate forms) administered in a dose of 500 mg four times a day for 3 weeks is the treatment of choice in pregnant women.…”

Section: Management Medical Managementmentioning

confidence: 99%

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Re‐emergence of lymphogranuloma venereum

Kapoor¹

2008

Acad Dermatol Venereol

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Lymphogranuloma venereum (LGV) is a sexually transmitted infection caused by the L1, L2 and L3 serotypes of Chlamydia trachomatis. The disease has been in the spotlight recently because of recent outbreaks in Europe as well as the USA. A unique feature of the recent outbreaks has been that most cases have been caused by the L2 strain. Another unique feature of these outbreaks is the fact that most cases have occurred in men having sex with men, and most patients have presented with proctitis. Interestingly, most recent cases have occurred in human immunodeficiency virus-seropositive patients. Usually, the disease is divided into three phases: the primary stage characterized by a self-healing papule, the secondary stage characterized by proctitis or lymphadenopathy and the tertiary stage characterized by lymphedema and anal strictures. Tests used for diagnosis include polymerase chain reactions and compliment fixation tests. The treatment of choice is doxycycline.

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Treatment of lymphogranuloma venereum with rifampicin.

Cited by 5 publications

References 2 publications

Use of rifampin in nonstaphylococcal, nonmycobacterial disease

Use of rifampin in nonstaphylococcal, nonmycobacterial disease

Effect of Azithromycin plus Rifampin versus That of Azithromycin Alone on the Eradication of Chlamydia pneumoniae from Lung Tissue in Experimental Pneumonitis

Re‐emergence of lymphogranuloma venereum

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