Treatment of guttural pouch mycosis

Abstract

Summary Seventeen cases of guttural pouch mycosis (including two bilaterally affected cases) were diagnosed in a three year period. The presenting signs were, in order of frequency, epistaxis at rest, nasal catarrh, pharyngeal paralysis, ipsilateral laryngeal hemiplegia, swelling of the submandibular/parotid region, extension of the head and neck and dyspnoea. Ligation of the origin of the internal carotid and occipital arteries was attempted in 10 of the cases exhibiting epistaxis. Bilateral ligation was performed on one animal with an untoward sequelae. Where surgery was successfully completed further haemorrhage was prevented in eight out of nine affected pouches (89 per cent). Medical treatment involving local administration of various antifungal preparations via a specially designed catheter and/or the oral administration of benzimidazole drugs was successful in eliminating the mycotic plaque in most cases. Cases which presented with pharyngeal paralysis were all fatal.

Dysphagia caused by focal guttural pouch mycosis: mononeuropathy of the pharyngeal ramus of the vagal nerve in a 20-year-old pony mare

“…According to Edwards and Greet (2007), a local treatment is indicated for neurological deficits [10]. Various antimycotics, such as nystatin, ketoconazole, miconazole, natamycin, enilconazole, clotrimazole in different pharmaceutical forms (powder, solutions), and thiobendazole, or irritant reducing solutions, such as povidone-iodine or 6% neomycin mixed with 1% gentian violet, can be used [9,10,12,14,22,23]. Unfortunately, a standard approach to the treatment of guttural pouch mycosis does not exist.…”

Differential Diagnosis and Management of Cranial Nerve Abnormalities

“…33 Of the two surviving horses, one had complete resolution of the dysphagia and the second horse still had low-grade dysphagia at discharge. 33 Church et al (1986) 34 reported that none of their five horses with dysphagia showed any improvement despite ligature of the internal carotid artery in one horse and lengthy medical treatment in the other four horses. The necessity of medical treatment is questioned by some clinicians.…”

Air Pollution and Domestic Animals

“…Most of these micro organisms are not considered as primary pathogens. Occasionally infection of the guttural pouch with Aspergilles fumigatus may occur (Church et al, 1986). The guttural pouch is a 300 mL diverticulum of the Eustachian tube (Fig 2).…”