Treatment of glaucoma in young nanophthalmic patients

Koçak, İncí; Altıntaş, Ayşe; Yalvaç, Ilgaz Saĝdiç; Nurözler, Ayşe Burcu; Kasim, Remzi; Duman, Sunay

doi:10.1007/bf00212955

Cited by 17 publications

(21 citation statements)

References 13 publications

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“…In 1997, we reported clinical course of glaucoma and early results of trabeculectomy þ MMC þ inferior sclerotomy in a small group of patients with nanophthalmos. 8,9 Mean IOP dropped from 39.3 to 19.3 mm Hg and none had postoperative uveal effusion, retinal detachment, visual loss or other major complications in the eyes of two patients in one of our studies. 9 This study is the continuum of the previous two and it is the first one comparing the long-term results of trabeculectomy þ MMC þ inferior sclerotomy for the patients with nanophthalmos.…”

Section: Discussionmentioning

confidence: 53%

“…8,9 Mean IOP dropped from 39.3 to 19.3 mm Hg and none had postoperative uveal effusion, retinal detachment, visual loss or other major complications in the eyes of two patients in one of our studies. 9 This study is the continuum of the previous two and it is the first one comparing the long-term results of trabeculectomy þ MMC þ inferior sclerotomy for the patients with nanophthalmos. The mean IOP dropped to 21.4177.34 mm Hg at last visit from 34.670.3 mm Hg preoperatively (Po0.05) Kaplan-Meier survival analysis demonstrated the success probabilities of 85, 78.4, 76.9, 70.6 and 47% at the first, second, third, fourth and fifth year, respectively, in our study.…”

Section: Discussionmentioning

confidence: 53%

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Management of glaucoma in patients with nanophthalmos

Yalvaç

Şatana

Özkan

et al. 2007

Eye

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Aims In this retrospective study, we aimed to evaluate the results of glaucoma surgery in patients with nanophthalmos. Methods Twenty-eight bilateral nanophthalmic patients, of whom 20 patients underwent trabeculectomy þ Mitomycin-C (MMC) þ inferior sclerotomy between 1996 and 2004, were included in this study. Records of patients with nanophthalmos were reviewed. Intraocular pressure (IOP), glaucoma medications, surgical success, visual acuity and complications were analyzed. Results The mean IOP was 34.675.3 mm Hg preoperatively. At the final follow-up visit, the mean IOP dropped to 21.4177.34 mm Hg (Po0.05). The cumulative probability of success was 85% at 1 year, 78.5% at 2 years, 76.9% at 3 years, 70.6% at 4 years and 47% at 5 years after surgery. Visual acuity decreased in 13 (65%) patients but no eye lost vision. Sequels of choroidal detachment (five patients 25%) and retinal folds (four patients 20%) were the most frequent reason for visual decrease. Uveal effusion (10 patients 50%) and cataract formation (seven patients 35%) were major late postoperative complications. Conclusions Results indicate that trabeculectomy þ MMC þ inferior sclerotomy procedure was effective and safe for glaucoma control in patients with nanophthalmos, but uveal effusion is a major problem and cataract surgery is expected in the long run.

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Section: Discussionmentioning

confidence: 53%

Section: Discussionmentioning

confidence: 53%

Management of glaucoma in patients with nanophthalmos

Yalvaç

Şatana

Özkan

et al. 2007

Eye

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“…2 In a schematic drawing of the eyeball (a) and a photomicrograph (b) of the left eye during surgery, a subscleral window under the scleral flap (asterisk) in the temporo-inferior quadrant can be seen (IR inferior rectus muscle, LR lateral rectus muscle) nanophthalmic eyes, also failed to achieve retinal reattachment in the right eye, probably because of postoperative adhesion of the scleral flap to the sclerectomy bed during wound healing [5]. Thus, we applied topical MMC to the scleral flap during surgery of the left eye, because the drug is used during filtering surgery to treat glaucoma [4]. Excellent surgical results have been reported for sclerectomy under the scleral flap without MMC in nanophthalmic eyes [6].…”

Section: Discussionmentioning

confidence: 97%

Scleral window surgery and topical mitomycin C for nanophthalmic uveal effusion complicated by renal failure: case report

Suzuki

Nishina

Azuma

2006

Graefe's Arch Clin Exp Ophthalmol

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“…Trabeculectomy has been reported to be effective for lowering IOP in patients with nanophthalmic glaucoma [12] . However, in our case series, the mean anterior chamber was extremely shallow (1.38 ± 0.10 mm) and much narrower than that (2.30 ± 0.36 mm) reported by Yalvac et al [13] .…”

Section: Discussionmentioning

confidence: 99%

“…Argon laser iridoplasty is an adjunctive treatment if the anterior chamber angle remains appositionally closed after iridectomy [11] . Ultimately, surgical management is required in eyes with uncontrolled intraocular pressure (IOP) due to the development of extensive PAS [12,13] . However, filtration surgery in these patients is quite challenging, mainly because of the high risk of intra-and postoperative complications [14,15] .…”

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confidence: 99%

Combined 23-G Pars Plana Vitrectomy and Lensectomy in the Management of Glaucoma Associated with Nanophthalmos

Zhang

Zhang²,

Jiang³

et al. 2017

Ophthalmic Res

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Purpose: To investigate the surgical results of 23-G pars plana vitrectomy (PPV) combined with lensectomy (PPL) in nanophthalmic patients with angle closure glaucoma. Methods: This prospective nonrandomized study included consecutive patients with nanophthalmic glaucoma recruited for 23-G PPV combined with PPL. Best-corrected visual acuity (BCVA), intraocular pressure (IOP), the number of antiglaucoma medications, and surgery-associated complications were recorded. Surgical success rates were evaluated at each follow-up. Prognostic factors for success were also assessed using logistic regression analysis. Results: This study enrolled 21 eyes of 21 patients. The mean follow-up was 18.6 ± 7.0 months. At the final follow-up visit, the mean IOP was significantly reduced (from 47.4 ± 5.7 to 18.6 ± 3.6 mm Hg). The mean number of antiglaucoma medications dropped from 5 to 0. BCVA improved in 3 (14.3%) eyes. The complete success rate (IOP >6 and <21 mm Hg without antiglaucoma medication) was 71.4, 66.7, and 71.4% at the 6-month, 12-month, and final follow-up visit, respectively. Conclusions: Nanophthalmic glaucoma can be effectively managed with the combined surgery of 23-G PPV and PPL. IOP control was achieved with elimination of pupillary block and deepening of the anterior chamber. This surgical procedure proved to be safe in eyes with a potential risk of vision-threatening complications.

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Treatment of glaucoma in young nanophthalmic patients

Cited by 17 publications

References 13 publications

Management of glaucoma in patients with nanophthalmos

Management of glaucoma in patients with nanophthalmos

Scleral window surgery and topical mitomycin C for nanophthalmic uveal effusion complicated by renal failure: case report

Combined 23-G Pars Plana Vitrectomy and Lensectomy in the Management of Glaucoma Associated with Nanophthalmos

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